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17 results on '"Brian Morris"'

1. The landscape of <scp> BRCA1 </scp> and <scp> BRCA2 </scp> large rearrangements in an international cohort of over 20 000 ovarian tumors identified using next‐generation sequencing

Author

Melanie A. Jones, Kirsten M. Timms, Shanell Hatcher, Elizabeth S. Cogan, Matthew S. Comeaux, Michael Perry, Brian Morris, Brad Swedlund, Cathy E. Elks, Pierre Lao‐Sirieix, Simon Dearden, Coumaran Egile, Jessica S. Brown, Elizabeth A. Harrington, Darren Hodgson, Matt Stern, Thomas P. Slavin, and Debora Mancini‐DiNardo

Subjects
Cancer Research, Genetics
Published
2023
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4. Insects as food among hunter-gatherers

Author

Brian Morris

Subjects
Ethnobiology, History, Folklore, Anthropology, Mythology, Cultural entomology, Recreation
Abstract

Insects are the most abundant terrestrial life-form, yet anthropologists on the whole have been little interested in insect life, although in recent decades with the emergence of ethnobiology and cultural entomology as sub-disciplines, a growing interest has developed in insect-human interactions. Thus scholars have been studying not only the practical uses of insects as food or medicine, but the role that insects have played in the cultural life of human societies - with regard to literature, mythology, music, art, religion, folklore and recreation (Bodenheimer 1951, Clausen 1954, Hogue 1987, Van Huis 1996). Here I shall focus on the role of insects as food.

Published
2008
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7. Can the Mothers of Invention Make Virtue out of Necessity? An optimistic deconstruction of research compromises in contract research and evaluation

Author

Julie Allan, Brian Morris, and Ian Stronach

Subjects
Research design, Virtue, Higher education, business.industry, media_common.quotation_subject, Postmodernism, Education, Epistemology, Educational research, Negotiation, Deconstruction (building), Hybridity, Law, Sociology, business, media_common
Abstract

This article offers a retrospective deconstruction of research compromises undertaken during ‘quick and dirty’ contract evaluation. The deconstruction identifies constraining changes in the nature of research contexts, but develops a positive view of methodological developments which might be regarded as creating ‘transgressive validity’. Notions of ‘hybridity’ in research methodology, and of ‘negotiation’ in research procedures are considered.

Published
1996
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8. Multiplexed measurement of candidate blood protein biomarkers of heart failure

Author

Claire Tonry, Ken McDonald, Mark Ledwidge, Belinda Hernandez, Nadezhda Glezeva, Cathy Rooney, Brian Morrissey, Stephen R. Pennington, John A. Baugh, and Chris J. Watson

Subjects
Heart failure, Biomarkers, Proteomics, MRM, BNP, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Aims There is a critical need for better biomarkers so that heart failure can be diagnosed at an earlier stage and with greater accuracy. The purpose of this study was to design a robust mass spectrometry (MS)‐based assay for the simultaneous measurement of a panel of 35 candidate protein biomarkers of heart failure, in blood. The overall aim was to evaluate the potential clinical utility of this biomarker panel for prediction of heart failure in a cohort of 500 patients. Methods and results Multiple reaction monitoring (MRM) MS assays were designed with Skyline and Spectrum Mill PeptideSelector software and developed using nanoflow reverse phase C18 chromatographic Chip Cube‐based separation, coupled to a 6460 triple quadrupole mass spectrometer. Optimized MRM assays were applied, in a sample‐blinded manner, to serum samples from a cohort of 500 patients with heart failure and non‐heart failure (non‐HF) controls who had cardiovascular risk factors. Both heart failure with reduced ejection fraction (HFrEF) patients and heart failure with preserved ejection fraction (HFpEF) patients were included in the study. Peptides for the Apolipoprotein AI (APOA1) protein were the most significantly differentially expressed between non‐HF and heart failure patients (P = 0.013 and P = 0.046). Four proteins were significantly differentially expressed between non‐HF and the specific subtypes of HF (HFrEF and HFpEF); Leucine‐rich‐alpha‐2‐glycoprotein (LRG1, P

Published
2021
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