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Your search keyword '"Bjork, James M"' showing total 14 results
Start Over Author "Bjork, James M" Publisher wiley
14 results on '"Bjork, James M"'

1. Development and clinical feasibility study of a brief version of an addiction‐focused phenotyping battery in females receiving buprenorphine for opioid use disorder

Author

Parlier‐Ahmad, Anna Beth, primary, Eglovitch, Michelle, additional, Legge, Catherine, additional, Keyser‐Marcus, Lori A., additional, Bjork, James M., additional, Adams, Amanda, additional, Ramey, Tanya, additional, Moeller, Frederick Gerard, additional, and Martin, Caitlin E., additional

Published
2023
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14. Mesolimbic recruitment by nondrug rewards in detoxified alcoholics: effort anticipation, reward anticipation, and reward delivery.

Author

Bjork JM, Smith AR, Chen G, and Hommer DW

Subjects
Adult, Behavior physiology, Brain Mapping, Corpus Striatum physiopathology, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Image Processing, Computer-Assisted, Impulsive Behavior psychology, Individuality, Magnetic Resonance Imaging, Male, Middle Aged, Motivation, Nucleus Accumbens physiopathology, Oxygen blood, Reaction Time physiology, Young Adult, Alcoholism physiopathology, Alcoholism psychology, Anticipation, Psychological physiology, Limbic System physiopathology, Recruitment, Neurophysiological physiology, Reward
Abstract

Aberrant sensitivity of incentive neurocircuitry to nondrug rewards has been suggested as either a risk factor for or consequence of drug addiction. Using functional magnetic resonance imaging, we tested whether alcohol-dependent patients (ADP: n = 29) showed altered recruitment of ventral striatal (VS) incentive neurocircuitry compared to controls (n = 23) by: (1) cues to respond for monetary rewards, (2) post-response anticipation of rewards, or (3) delivery of rewards. Using an instrumental task with two-stage presentation of reward-predictive information, subjects saw cues signaling opportunities to win $0, $1, or $10 for responding to a target. Following this response, subjects were notified whether their success would be indicated by a lexical notification (“Hit?”) or by delivery of a monetary reward (“Win?”). After a variable interval, subjects then viewed the trial outcome. We found no significant group differences in voxelwise activation by task contrasts, or in signal change extracted from VS. Both ADP and controls showed significant VS and other limbic recruitment by pre-response reward anticipation. In addition, controls also showed VS recruitment by post-response reward-anticipation, and ADP had appreciable subthreshold VS activation. Both groups also showed similar mesolimbic responses to reward deliveries. Across all subjects, a questionnaire measure of “hot” impulsivity correlated with VS recruitment by post-response anticipation of low rewards and with VS recruitment by delivery of low rewards. These findings indicate that incentive-motivational processing of nondrug rewards is substantially maintained in recovering alcoholics, and that reward-elicited VS recruitment correlates more with individual differences in trait impulsivity irrespective of addiction.

Published
2012
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