1. Exploratory Analysis of Cerebral Oxygen Reserves During Sleep Onset in Older and Younger Adults
- Author
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John Carlson, Virginia J. Neelon, Sunil Dogra, Barbara W. Carlson, and Marilyn Hartman
- Subjects
Gerontology ,Geriatrics ,Pediatrics ,medicine.medical_specialty ,Sleep Stages ,medicine.diagnostic_test ,business.industry ,Polysomnography ,Sleep in non-human animals ,Hypoxemia ,medicine ,Circadian rhythm ,Geriatrics and Gerontology ,Young adult ,medicine.symptom ,Sleep onset ,business - Abstract
OBJECTIVES: To explore differences in cerebral oxygen reserves during sleep in old and young adults. DESIGN: Descriptive cross-sectional study. SETTING: General clinical research center. PARTICIPANTS: Nine old (aged 65–84) and 10 young (aged 21–39) adults. MEASUREMENTS: Subjects were monitored during the first nightly sleep cycle using standard polysomnography, including measures of arterial oxyhemoglobin saturation (SaO2). Changes in regional cerebral oxyhemoglobin saturation (rcSO2) were used to estimate cerebral oxygen reserves. General linear models were used to test group differences in the change in SaO2 and rcSO2 during sleep.
- Published
- 2008
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