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1. Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey

Author

Murat Sayan, Ayse Arikan, and Murat Isbilen

Subjects
Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

The diagnosis of new variants and monitoring their potential effects on diagnosis, therapeutics, and vaccines by genomic sequencing is essential to manage global public crises. In the current study, spike-genome next-generation sequencing was generated from 492 SARS-CoV-2 isolates to evaluate the mutations in Turkey from April 2021 to February 2022. The variant analysis was performed using (Coronavirus Antiviral and Resistance Database (CoV-RDB) by Stanford University). We revealed that the lineages Alpha (B.1.1.7), Beta (B.1.351), Delta (B.1.617.2), Eta (B.1.525), variant of interest (VOI), lota (B.1.526), Zeta (P.2), Omicron (B.1.1.529), and Omicron BA.1 (B.1.1.529.1) were in the circulation in Turkey during the given period. The most common lineages were B.1.1.7, B.1.617.2, B.1.1.529, and B.1.1.529.1 SARS-CoV-2 variant circulation in Turkey seems highly heterogenetic; however, quite similar to the global epidemiologic analysis. The existence of globally circulating variants in the same chronological order in Turkey can be a guide for precautions, treatment, and vaccine options to be taken in the future.

Published
2022
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2. Gastric residual volume measurement in the intensive care unit: an international survey reporting nursing practice

Author

Ozen, Nurten, Blot, Stijn, Ozen, Volkan, Donmez, Ayse Arikan, Gurun, Pinar, Cinar, Fatma Ilknur, Labeau, Sonia, İstinye Üniversitesi, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümü, and Ozen, Nurten

Subjects
Enteral Nutrition, Nurse, Gastric Residual Volume, Intensive Care Unit, Guideline
Abstract

Background: Gastric residual volume measurement is routinely used to evaluate the feeding tolerance and gastro-oesophageal reflux in patients receiving enteral feeding therapy in the intensive care unit. However, little supportive evidence for this intervention is available as the usefulness of gastric residual volume measurements in patients receiving enteral feeding therapy in the intensive care is controversial. Aim: The aim of this study was to assess the practice of intensive care unit nurses related to gastric residual volume measurement in patients receiving enteral nutrition. Methods: A survey was conducted among a sample of intensive care unit nurses (n = 832) from four hospitals in Turkey (n = 182) and attendees of the Annual Congress of the Flemish Society for Critical Care Nurses in Flanders, Belgium (n = 650). The survey instrument was developed by the researchers based on the related literature. Results: A total of 480 nurses completed the questionnaire (response rate = 73%). Gastric residual volume is measured by 98.0% of respondents, with wide variations in the frequency of measuring. A 50-200 mL gastric residual volume is considered problematic by 45.5% (n = 183) of the participants, and only 18.4% (n = 81) reported their practice to be based on a current guideline. Strikingly, more experienced intensive care unit nurses appear to perform gastric residual volume measurements more commonly than their less experienced colleagues (p = 0.004), while the practice is more often reported to be performed in Belgium than in Turkey (p < 0.001). Conclusion: Gastric residual volume management could be improved by applying current evidence to daily nursing practice. WOS:000442347700008 30039544 Q2

Published
2018

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