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Your search keyword '"Ausems, M.G.E.M."' showing total 7 results
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7 results on '"Ausems, M.G.E.M."'

2. Performance of BRCA1/ 2 mutation prediction models in male breast cancer patients

Author

Moghadasi, S., primary, Grundeken, V., additional, Janssen, L.A.M., additional, Dijkstra, N.H., additional, Rodríguez-Girondo, M., additional, van Zelst-Stams, W.A.G., additional, Oosterwijk, J.C., additional, Ausems, M.G.E.M., additional, Oldenburg, R.A., additional, Adank, M.A., additional, Blom, E.W., additional, Ruijs, M.W.G., additional, van Os, T.A.M., additional, van Deurzen, C.H.M., additional, Martens, J.W.M., additional, Schroder, C.P., additional, Wijnen, J.T., additional, Vreeswijk, M.P.G., additional, and van Asperen, C.J., additional

Published
2017
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3. Improved Overall Survival after Contralateral Risk-Reducing Mastectomy in Brca1/2 Mutation Carriers with a History of Unilateral Breast Cancer: A Prospective Analysis

Author

Heemskerk-Gerritsen, B.A.M., Rookus, M.A., Aalfs, C.M., Ausems, M.G.E.M., Collee, J.M., Jansen, L., Kets, C.M., Keymeulen, K.B.M.I., Koppert, L.B., Meijers-Heijboer, H.E.J., Mooij, T.M., Tollenaar, R.A.E.M., Vasen, H.F.A., Hooning, M.J., Seynaeve, C., HEBON, Human Genetics, CCA -Cancer Center Amsterdam, ARD - Amsterdam Reproduction and Development, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Targeted Gynaecologic Oncology (TARGON), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), MUMC+: MA Heelkunde (9), RS: GROW - Oncology, RS: GROW - R4 - Reproductive and Perinatal Medicine, Human genetics, CCA - Oncogenesis, Medical Oncology, Clinical Genetics, and Surgery

Subjects
Oncology, Cancer Research, SURGERY, medicine.medical_treatment, Genes, BRCA2, Genes, BRCA1, FAMILIES, prevention, contralateral risk-reducing mastectomy, Prospective Studies, Non-U.S. Gov't, PREDICTORS, skin and connective tissue diseases, Mastectomy, Aged, 80 and over, Medicine(all), OUTCOMES, Research Support, Non-U.S. Gov't, Hazard ratio, PROPHYLACTIC MASTECTOMY, WOMEN, GERMLINE MUTATIONS, Middle Aged, Multicenter Study, Cohort, Female, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], Adult, medicine.medical_specialty, Breast Neoplasms, Research Support, survival, OVARIAN-CANCER, breast cancer, Breast cancer, SDG 3 - Good Health and Well-being, Internal medicine, Journal Article, medicine, Humans, Aged, Proportional hazards model, business.industry, MORTALITY, Prophylactic Mastectomy, BRCA1, EFFICACY, medicine.disease, Confidence interval, Surgery, Mutation, Ovarian cancer, business
Abstract

Data on survival of BRCA1/2-associated primary breast cancer (PBC) patients who opt for subsequent contralateral risk-reducing mastectomy (CRRM) are scarce and inconsistent. We examined the efficacy of CRRM on overall survival in mutation carriers with a history of PBC. From a Dutch multicentre cohort, we selected 583 BRCA-associated PBC patients, being diagnosed between 1980 and 2011. Over time, 242 patients (42%) underwent CRRM and 341 patients (58%) remained under surveillance. Survival analyses were performed using Cox models, with CRRM as a time-dependent covariate. The median follow-up after PBC diagnosis was 11.4 years. In the CRRM group, four patients developed contralateral breast cancer (2%), against 64 patients (19%) in the surveillance group (p

Published
2014

7. Asymptomatic and lateonset ornithine transcarbamylase deficiency caused by a A208T mutation: Clinical, biochemical and DNA analyses in a four‐generation family

Author

Ausems, M.G.E.M., primary, Bakker, E., additional, Berger, R., additional, Duran, M., additional, van Diggelen, O.P., additional, Keulemans, J.L.M., additional, de Valk, H.W., additional, Kneppers, A.L.J., additional, Dorland, L., additional, Eskes, P.F., additional, Beemer, F.A., additional, Poll‐The, B.T., additional, and Smeitink, J.A.M., additional

Published
1997
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