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Your search keyword '"Ahmed, Hashim U."' showing total 39 results
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39 results on '"Ahmed, Hashim U."'

1. External validation of a risk model predicting failure of salvage focal ablation for prostate cancer

Author

Light, Alexander, primary, Peters, Max, additional, Reddy, Deepika, additional, Kanthabalan, Abi, additional, Otieno, Marjorie, additional, Pavlou, Menelaos, additional, Omar, Rumana, additional, Adeleke, Sola, additional, Giganti, Francesco, additional, Brew‐Graves, Chris, additional, Williams, Norman R., additional, Emara, Amr, additional, Haroon, Athar, additional, Latifoltojar, Arash, additional, Sidhu, Harbir, additional, Freeman, Alex, additional, Orczyk, Clement, additional, Nikapota, Ashok, additional, Dudderidge, Tim, additional, Hindley, Richard G., additional, Virdi, Jaspal, additional, Arya, Manit, additional, Payne, Heather, additional, Mitra, Anita V., additional, Bomanji, Jamshed, additional, Winkler, Mathias, additional, Horan, Gail, additional, Moore, Caroline, additional, Emberton, Mark, additional, Punwani, Shonit, additional, Ahmed, Hashim U., additional, and Shah, Taimur T., additional

Published
2023
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3. Accurate diagnosis of prostate cancer by combining Proclarix with magnetic resonance imaging

Author

Morote, Juan, primary, Pye, Hayley, additional, Campistol, Miriam, additional, Celma, Anna, additional, Regis, Lucas, additional, Semidey, Maria, additional, de Torres, Ines, additional, Mast, Richard, additional, Planas, Jacques, additional, Santamaria, Anna, additional, Trilla, Enrique, additional, Athanasiou, Alcibiade, additional, Singh, Saurabh, additional, Heavey, Susan, additional, Stopka‐Farooqui, Urszula, additional, Freeman, Alex, additional, Haider, Aiman, additional, Schiess, Ralph, additional, Whitaker, Hayley C., additional, Punwani, Shonit, additional, Ahmed, Hashim U., additional, and Emberton, Mark, additional

Published
2023
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4. The rapid assessment for prostate imaging and diagnosis ( RAPID ) prostate cancer diagnostic pathway

Author

Eldred‐Evans, David, primary, Connor, Martin J., additional, Bertoncelli Tanaka, Mariana, additional, Bass, Edward, additional, Reddy, Deepika, additional, Walters, Uma, additional, Stroman, Luke, additional, Espinosa, Easter, additional, Das, Raj, additional, Khosla, Nalin, additional, Tam, Henry, additional, Pegers, Elizabeth, additional, Qazi, Hasan, additional, Gordon, Stephen, additional, Winkler, Mathias, additional, and Ahmed, Hashim U., additional

Published
2022
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5. Outcomes of the RAFT trial: robotic surgery after focal therapy

Author

Cathcart, Paul, primary, Ribeiro, Luis, additional, Moore, Caroline, additional, Ahmed, Hashim U., additional, Leslie, Tom, additional, Arya, Manit, additional, Orczyk, Clement, additional, Hindley, Richard G., additional, Cahill, Fidelma, additional, Prendergast, Aaron, additional, Coetzee, Carike, additional, Yogeswaran, Yathushan, additional, Tunna, Kirsty, additional, Sooriakumaran, Prasanna, additional, and Emberton, Mark, additional

Published
2021
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6. Added value of diffusion-weighted images and dynamic contrast enhancement in multiparametric magnetic resonance imaging for the detection of clinically significant prostate cancer in the PICTURE trial

Author

Eldred-Evans, David, Neves, Joana B, Simmons, Lucy AM, Kanthabalan, Abi, McCartan, Neil, Shah, Taimur T, Arya, Manit, Charman, Susan C, Freeman, Alex, Moore, Caroline M, Punwani, Shonit, Emberton, Mark, and Ahmed, Hashim U

Abstract

Objective To determine the additional diagnostic value of diffusion‐weighted imaging (DWI) and dynamic contrast‐enhanced (DCE) imaging in men requiring a repeat biopsy within the PICTURE study. Patients and Methods PICTURE was a paired‐cohort confirmatory study in which 249 men who required further risk stratification following a previous non‐MRI guided TRUS biopsy underwent a 3‐Tesla mpMRI consisting of T2W, DWI and DCE followed by transperineal template prostate mapping (TPM) biopsy. Each mpMRI was reported using a LIKERT score in a sequential blinded manner to generate scores for T2W, T2W+DWI and T2W+DWI+DCE. Area under the receiver operating characteristic (AUROC) fanalysis was performed to compare the diagnostic accuracy of each combination. The threshold for a positive mpMRI was set as a LIKERT score >/=3. Clinically significant prostate cancer was analysed across a range of definitions including UCL/Ahmed Definition 1 (primary definition), UCL/Ahmed Definition 2, any Gleason >/=3+4 and any Gleason >/=4+3. Results Of 249, sequential MRI reporting was available for 246. There was a higher rate of equivocal lesions (44.6%) using T2W alone compared to the addition of DWI (23.9%) and DCE (19.8%). Using the primary definition of clinically significant disease, there was no significant difference in the overall accuracy between T2W at AUROC 0.74 (95% CI 0.68‐0.80), T2W+DWI at 0.76 (95% CI 0.71‐0.82) and T2W+DWI+DCE at 0.77 (95% CI 0.71‐0.82) (p=0.55). The AUROCs remained comparable using other definitions of clinically significant disease including UCL/Ahmed 2 (p=0.79), Gleason >/=3+4 (p=0.53) and Gleason >/=4+3 (p=0.53). Conclusions Using a 3T MRI, a high level of diagnostic accuracy can be achieved using T2W as a single parameter in men with a prior biopsy. However, such a strategy can lead to a higher rate of equivocal lesions.

Published
2019

7. Certification in reporting multiparametric magnetic resonance imaging of the prostate: recommendations of a UK consensus meeting

Author

Barrett, Tristan, primary, Padhani, Anwar R., additional, Patel, Amit, additional, Ahmed, Hashim U., additional, Allen, Clare, additional, Bardgett, Harry, additional, Belfield, Jane, additional, Brizmohun Appayya, Mrishta, additional, Harding, Thomas, additional, Hoch, Ornella‐Shanin, additional, Keanie, Julian Y., additional, Liyanage, Sidath H., additional, Papoutsaki, Marianthi‐Vasiliki, additional, Punwani, Shonit, additional, Robinson, Mark J.C., additional, Rajesh, Arumugam, additional, Staffurth, John N., additional, Meulen, Jan, additional, and Richenberg, Jonathan, additional

Published
2020
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9. Evaluation of functional outcomes after a second focal high-intensity focused ultrasonography (HIFU) procedure in men with primary localized, non-metastatic prostate cancer: results from the HIFU Evaluation and Assessment of Treatment (HEAT) registry

Author

Lovegrove, Catherine E., primary, Peters, Max, additional, Guillaumier, Stephanie, additional, Arya, Manit, additional, Afzal, Naveed, additional, Dudderidge, Tim, additional, Hosking-Jervis, Feargus, additional, Hindley, Richard G., additional, Lewi, Henry, additional, McCartan, Neil, additional, Moore, Caroline M., additional, Nigam, Raj, additional, Ogden, Chris, additional, Persad, Raj, additional, Virdi, Jaspal, additional, Winkler, Mathias, additional, Emberton, Mark, additional, Ahmed, Hashim U., additional, Shah, Taimur T., additional, and Minhas, Suks, additional

Published
2020
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10. Likert vs PI‐RADS v2: a comparison of two radiological scoring systems for detection of clinically significant prostate cancer

Author

Khoo, Christopher C., primary, Eldred‐Evans, David, additional, Peters, Max, additional, Bertoncelli Tanaka, Mariana, additional, Noureldin, Mohamed, additional, Miah, Saiful, additional, Shah, Taimur, additional, Connor, Martin J., additional, Reddy, Deepika, additional, Clark, Martin, additional, Lakhani, Amish, additional, Rockall, Andrea, additional, Hosking‐Jervis, Feargus, additional, Cullen, Emma, additional, Arya, Manit, additional, Hrouda, David, additional, Qazi, Hasan, additional, Winkler, Mathias, additional, Tam, Henry, additional, and Ahmed, Hashim U., additional

Published
2019
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12. Medium-term oncological outcomes in a large cohort of men treated with either focal or hemi-ablation using high-intensity focused ultrasonography for primary localized prostate cancer

Author

Stabile, Armando, primary, Orczyk, Clement, additional, Hosking-Jervis, Feargus, additional, Giganti, Francesco, additional, Arya, Manit, additional, Hindley, Richard G., additional, Dickinson, Louise, additional, Allen, Clare, additional, Punwani, Shonit, additional, Jameson, Charles, additional, Freeman, Alex, additional, McCartan, Neil, additional, Montorsi, Francesco, additional, Briganti, Alberto, additional, Ahmed, Hashim U., additional, Emberton, Mark, additional, and Moore, Caroline M., additional

Published
2019
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14. A core outcome set for localised prostate cancer effectiveness trials

Author

MacLennan, Steven, Williamson, Paula R., Bekema, Hanneke, Campbell, Marion, Ramsay, Craig, N'Dow, James, MacLennan, Sara, Vale, Luke, Dahm, Philipp, Mottet, Nicolas, Lam, Thomas, Abel, Paul, Ahmed, Hashim U., Akehurst, Gary, Almquist, Robert, Beck, Karl, Budd, David, Canfield, Steven, Catto, James, Cornford, Philip, Cross, William, Ewen, Alexander, Grant, Judith, Heer, Rakesh, Hurst, David, Jones, Rob, Kockelbergh, Roger, Mackie, Andrew, MacDonald, Graham, McNeill, Alan, Mason, Malcolm, McClinton, Sam, McLaren, Duncan, Mostafid, Hugh, Pearce, Ian, Pennet, Linda, Royle, Justine, Schreuder, Hans, Stewart, Grant D., van der Poel, Henk, Wardlaw, Kevin, and Wiegel, Thomas

Abstract

Objective: \ud \ud To develop a core outcome set (COS) applicable for effectiveness trials of all interventions for localised prostate cancer.\ud Background: \ud \ud Many treatments exist for localised prostate cancer, although it is unclear which offers the optimal therapeutic ratio. This is confounded by inconsistencies in the selection, definition, measurement and reporting of outcomes in clinical trials.\ud Subjects and methods: \ud \ud A list of 79 outcomes was derived from a systematic review of published localised prostate cancer effectiveness studies and semi-structured interviews with 15 prostate cancer patients. A two-stage consensus process involving 118 patients and 56 international healthcare professionals (HCPs) (cancer specialist nurses, urological surgeons and oncologists) was undertaken, consisting of a three-round Delphi survey followed by a face-to-face consensus panel meeting of 13 HCPs and 8 patients.\ud Results: \ud \ud The final COS included 19 outcomes. Twelve apply to all interventions: death from prostate cancer, death from any cause, local disease recurrence, distant disease recurrence/metastases, disease progression, need for salvage therapy, overall quality of life, stress urinary incontinence, urinary function, bowel function, faecal incontinence, sexual function. Seven were intervention-specific: perioperative deaths (surgery), positive surgical margin (surgery), thromboembolic disease (surgery), bothersome or symptomatic urethral or anastomotic stricture (surgery), need for curative treatment (active surveillance), treatment failure (ablative therapy), and side effects of hormonal therapy (hormone therapy). The UK-centric participants may limit the generalisability to other countries, but trialists should reason why the COS would not be applicable. The default position should not be that a COS developed in one country will automatically not be applicable elsewhere.\ud Conclusion: \ud \ud We have established a COS for trials of effectiveness in localised prostate cancer, applicable across all interventions which should be measured in all localised prostate cancer effectiveness trials.

Published
2017

15. Immunohistochemical biomarker validation in highly selective needle biopsy microarrays derived from mpMRI-characterized prostates

Author

Olivier, Jonathan, primary, Stavrinides, Vasilis, additional, Kay, Jonathan, additional, Freeman, Alex, additional, Pye, Hayley, additional, Ahmed, Zeba, additional, Carmona Echeverria, Lina, additional, Heavey, Susan, additional, Simmons, Lucy A. M., additional, Kanthabalan, Abi, additional, Arya, Manit, additional, Briggs, Tim, additional, Barratt, Dean, additional, Charman, Susan C., additional, Gelister, James, additional, Hawkes, David, additional, Hu, Yipeng, additional, Jameson, Charles, additional, McCartan, Neil, additional, Punwani, Shonit, additional, van der Muelen, Jan, additional, Moore, Caroline, additional, Emberton, Mark, additional, Ahmed, Hashim U., additional, and Whitaker, Hayley C., additional

Published
2018
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16. National implementation of multi-parametric magnetic resonance imaging for prostate cancer detection - recommendations from a UK consensus meeting

Author

Brizmohun Appayya, Mrishta, primary, Adshead, Jim, additional, Ahmed, Hashim U., additional, Allen, Clare, additional, Bainbridge, Alan, additional, Barrett, Tristan, additional, Giganti, Francesco, additional, Graham, John, additional, Haslam, Phil, additional, Johnston, Edward W., additional, Kastner, Christof, additional, Kirkham, Alexander P.S., additional, Lipton, Alexandra, additional, McNeill, Alan, additional, Moniz, Larissa, additional, Moore, Caroline M., additional, Nabi, Ghulam, additional, Padhani, Anwar R., additional, Parker, Chris, additional, Patel, Amit, additional, Pursey, Jacqueline, additional, Richenberg, Jonathan, additional, Staffurth, John, additional, van der Meulen, Jan, additional, Walls, Darren, additional, and Punwani, Shonit, additional

Published
2018
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17. Technical Note: Error metrics for estimating the accuracy of needle/instrument placement during transperineal magnetic resonance/ultrasound‐guided prostate interventions

Author

Bonmati, Ester, primary, Hu, Yipeng, additional, Villarini, Barbara, additional, Rodell, Rachael, additional, Martin, Paul, additional, Han, Lianghao, additional, Donaldson, Ian, additional, Ahmed, Hashim U., additional, Moore, Caroline M., additional, Emberton, Mark, additional, and Barratt, Dean C., additional

Published
2018
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24. Scoring systems used for the interpretation and reporting of multiparametric MRI for prostate cancer detection, localization, and characterization: could standardization lead to improved utilization of imaging within the diagnostic pathway?

Author

Dickinson, Louise, primary, Ahmed, Hashim U., additional, Allen, Clare, additional, Barentsz, Jelle O., additional, Carey, Brendan, additional, Futterer, Jurgen J., additional, Heijmink, Stijn W., additional, Hoskin, Peter, additional, Kirkham, Alex P., additional, Padhani, Anwar R., additional, Persad, Raj, additional, Puech, Philippe, additional, Punwani, Shonit, additional, Sohaib, Aslam, additional, Tombal, Bertrand, additional, Villers, Arnauld, additional, and Emberton, Mark, additional

Published
2012
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25. A biopsy simulation study to assess the accuracy of several transrectal ultrasonography (TRUS)-biopsy strategies compared with template prostate mapping biopsies in patients who have undergone radical prostatectomy

Author

Hu, Yipeng, primary, Ahmed, Hashim U., additional, Carter, Tim, additional, Arumainayagam, Nimalan, additional, Lecornet, Emilie, additional, Barzell, Winston, additional, Freeman, Alex, additional, Nevoux, Pierre, additional, Hawkes, David J., additional, Villers, Arnauld, additional, Emberton, Mark, additional, and Barratt, Dean C., additional

Published
2012
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