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Abstract Introduction Epistemic trust, or trust in transmitted knowledge, has been proposed as a critical factor in psychopathology and psychotherapy. This study aimed at evaluating the psychometric properties of the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) in Iran. Method Data were collected from 906 participants. Along with the ETMCQ, measures of mentalizing, mindfulness, perspective‐taking, attachment, emotion dysregulation, and borderline personality disorder were administered. Confirmatory factor analysis and exploratory structural equation modeling (ESEM) were used to determine factorial structure. Results The ESEM model showed an acceptable fit and outperformed the confirmatory model. A 14‐item version of the ETMCQ was retained after examining item performance. Our findings also established criterion‐related validity for mistrust and credulity, an acceptable internal consistency for credulity, discriminant power for mistrust and credulity in detecting positive screens for borderline personality disorder, and measurement invariance across sexes. Conclusion This study provides evidence for the cross‐cultural applicability of the ETMCQ. Nonetheless, the validity of the trust and internal consistency of the mistrust subscale require particular attention in future research.

Abstract Background Ocular hypertension is one of the most underdiagnosed ocular abnormalities among guinea pigs around the world. Objectives The current study investigates the effect of 0.0015% preservative‐free tafluprost ophthalmic solution (Zioptan) on the intraocular pressure of 16 healthy male guinea pigs (Cavia porcellus) under different light/darkness regimes. Methods All guinea pigs received a single drop of tafluprost at 5:30 in the right eye, whereas the contralateral eyes served as control to receive a placebo. Then, the animals were randomly divided into two groups; group A was exposed to light, whereas group B was placed in darkness from 5:30 to 18:00. Rebound tonometry (TonoVet) was instrumented to measure IOP values at 5:30 (baseline), 6:00, 7:00, 8:00, 9:00 and then every 3 h until 18:00. Results The maximum IOP reduction associated with tafluprost was observed at 6:00 by −1.4 ± 1.1 mmHg (p‐value = 0.026) and −2.5 ± 1.2 mmHg (p‐value = 0.011) in group A and B, respectively (repeated measure ANOVA test). There was a significant difference between the mean right and left eye IOP values in both groups at 5:30, 6:00, 7:00 and 8:00 (p‐value

Abstract Objectives The purpose of this study was to evaluate conjunctival microflora and measure normal tear production and intraocular pressure (IOP) in two breeds of hedgehogs (long‐eared hedgehogs and Brandt's hedgehogs). Methods Forty‐eight hedgehogs from two different breeds were chosen for the study. Tear production was measured using the Schirmer tear test (STT) and phenol red thread test (PRTT) in both eyes. IOP was measured using a rebound tonometer. To perform microbiological sampling one drop of tetracaine was instilled in the eyes. Two sterile microswabs were used to collect samples for the microbial and fungal culture. All the microswab samples were transferred in phosphate‐buffered saline (PBS) to the laboratory for culture. Two MacConkey and two blood agar media plates were employed for each eye. Oneplate of sabouraud dextrose agar (SDA) was used for the fungal culture for each eye. Standard biochemical tests were performed to identify the isolated organisms. Results The mean STT and PRTT values were 1.6 ± 0.1 mm/min and 2.4 ± 0.3 mm/15 s in long‐eared hedgehogs and 2.2 ± 0.1 mm/min and 2.5 ± 0.3 mm/15 s in Brandt's hedgehogs, respectively. Mean (SD) Intraocular pressure of right eyes in long‐eared hedgehog and Brandt hedgehog were 19.7 ± 1.4 mmHg and 19.2 ± 2.4 mmHg, respectively. In the left eyes of long‐eared hedgehog and Brandt hedgehog mean (SD) IOP were 19.8 ± 1.5 mmHg and 19.5 ± 2.1 mmHg, respectively. In long‐eared hedgehogs, the most common bacteria were Staphylococcus epidermidis and Bacillus spp. In Brandt's hedgehogs, 24 out of 48 eyes had Staphylococcus epidermidis, which was the most commonly isolated bacterial species. Conclusions This study established reference intervals for IOP, STT and PRTT in hedgehogs and recognised and compared ocular conjunctival microflora in two breeds of hedgehogs.

Abstract Aim We intended to elucidate the relationship between mentalizing capacity and affective states by investigating the mediatory role of emotion dysregulation. Methods A sample of nonclinical Iranian adults (N = 445) completed a battery of online self‐report measures comprising the Positive and Negative Affect Schedule (PANAS), Mentalization Scale (MentS), and Difficulties in Emotion Regulation Scale (DERS). Results Correlational analyses demonstrated that self‐ and other‐related mentalizing were significantly and inversely associated with emotion dysregulation, which in turn was strongly linked with positive and negative affects. Using structural equation modeling, the results delineated emotion dysregulation as a mediator between self‐ and other‐related mentalizing and affective states, predicting higher negative and lower positive affects. However, motivation to mentalize failed to predict positive affects and only contributed to lower negative affects directly. Conclusion Mentalizing capacity was found to be indirectly linked with affective states through emotion dysregulation; hence, along with the previously substantiated association between emotion dysregulation and affective states and the partially established relationship between mentalizing capacity and affective states, we propose mentalizing incapacity to be at fault in the development of affective difficulties.

Abstract Introduction Mentalizing incapacity is increasingly identified as a common factor in psychopathology. The Mentalization Scale (MentS) is a cost‐effective measure built upon the dimensional model of mentalizing. We aimed to evaluate the psychometric properties of the Iranian version of MentS. Methods Two samples of community‐based adults (N1 = 450, N2 = 445) completed different batteries of self‐report measures. In addition to MentS, participants completed measures of reflective functioning and attachment insecurities in the first sample and a measure of emotion dysregulation in the second sample. Results Due to the conflicting results of confirmatory and exploratory factor analyses, an item‐parceling approach was applied, which replicated the original three‐factor structure of MentS, yielding Self‐Related Mentalization, Other‐Related Mentalization, and Motivation to Mentalize. The reliability and convergent validity of MentS were supported in both samples. Conclusion Our findings provided preliminary evidence for using the Iranian version of MentS in nonclinical populations as a reliable and valid measure.

Abstract In recent years, coreless axial‐flux permanent‐magnet (AFPM) machines have been gaining attention. Being coreless, these machines do not experience eddy current (hence hysteresis losses) and has lower cogging torque leading to higher efficiency. However, limitations such as high leakage flux and weak mechanical structure impede its wide application. The results of a systematic review on coreless AFPM machine research is presented, wherein a total of 123 studies have been selected through the Preferred Reported Items for Systematic Reviews and Meta‐Analysis (PRISMA) protocol. About 55% of the articles have been published between 2017 and 2021, indicating recent attention of the researchers on coreless AFPM machines. More than 70% (87 out of 123) of the records have been published by IEEE, which proves the quality and acceptance of the studies. In two‐thirds (77 out of 123) of the studies, single‐stator double‐rotor has been adopted as the machine topology, and in 71.8% (84 out of 123) cases, trapezoidal shape magnets have been used in conventional array. The key research areas on coreless AFPM identified through this review are to produce an efficient design for multiphase and multi‐stage topology and develop lightweight rotor and stator structures.

Abstract Background CD44, as a tumor‐associated marker, can be used to detect stem cells in breast cancer. While CD44 is expressed in normal epithelial cells, carcinoma cells overexpress CD44. Aims In the current study, we designed a recombinant protein that included the variable component of the CD44 (CD44v) extracellular domain to apply in clinical diagnosis of breast cancer. Methods A total of 100 CD44v amino‐acid residues were determined, and the structure was examined using bioinformatics tools. The construct was inserted into the PET28a vector and transformed in E. coli BL21(DE3). A nearly 12 kDa fusion protein was obtained by Ni‐NTA affinity metal chromatography. Recombinant CD44v was examined by Western blotting, ELISA, and immunohistochemistry (IHC) assays. Results The findings revealed that the structure of rCD44v was stable, and its antigenic domain was exposed. The recombinant CD44v was confirmed by western blotting, and the presence of antibodies against recombinant CD44v protein in the patient's serum was detected by the ELISA. Our data demonstrated a link between CD44v serum levels and the prevalence of breast cancer. Conclusion Assessments of antiCD44v antibodies with rCD44v could be a useful tool for identifying breast cancer in its early stages, which can lead to better outcomes.