807 results on '"A. Cava"'
Search Results
2. Psychophysical, electrofunctional, and morphological evaluation in naïve neovascular AMD patients treated with intravitreal anti‐VEGF
- Author
-
Nebbioso, Marcella, primary, Franzone, Federica, additional, Milanese, Alberto, additional, Artico, Marco, additional, Taurone, Samanta, additional, La Cava, Maurizio, additional, Livani, Maria Luisa, additional, Bonfiglio, Vincenza, additional, and Vestri, Annarita, additional more...
- Published
- 2024
- Full Text
- View/download PDF
Catalog
3. Adeno‐Associated Virus Type 5 Infection via PDGFRα Is Associated With Interstitial Lung Disease in Systemic Sclerosis and Generates Composite Peptides and Epitopes Recognized by the Agonistic Immunoglobulins Present in Patients With Systemic Sclerosis
- Author
-
Moroncini, Gianluca, primary, Svegliati, Silvia, additional, Grieco, Antonella, additional, Cuccioloni, Massimiliano, additional, Mozzicafreddo, Matteo, additional, Paolini, Chiara, additional, Agarbati, Silvia, additional, Spadoni, Tatiana, additional, Amoresano, Angela, additional, Pinto, Gabriella, additional, Chen, Qingxin, additional, Benfaremo, Devis, additional, Tonnini, Cecilia, additional, Senzacqua, Martina, additional, Alizzi, Silvia, additional, Nieto, Karen, additional, Finke, Doreen, additional, Viola, Nadia, additional, Amico, Donatella, additional, Galgani, Mario, additional, Gasparini, Stefano, additional, Zuccatosta, Lina, additional, Menzo, Stefano, additional, Müller, Martin, additional, Kleinschmidt, Jürgen, additional, Funaro, Ada, additional, Giordano, Antonio, additional, La Cava, Antonio, additional, Dorfmüller, Peter, additional, Amoroso, Antonio, additional, Pucci, Piero, additional, Pezone, Antonio, additional, Avvedimento, Enrico V., additional, and Gabrielli, Armando, additional more...
- Published
- 2024
- Full Text
- View/download PDF
4. Challenges and directions for open ecosystems biodiversity restoration: An overview of the techniques applied for Cerrado
- Author
-
Natashi A. L. Pilon, Bruna H. Campos, Giselda Durigan, Mário G. B. Cava, Lucy Rowland, Isabel Schmidt, Alexandre Sampaio, and Rafael S. Oliveira
- Subjects
Ecology - Published
- 2023
- Full Text
- View/download PDF
5. Photocatalytic performance of Al and Nb‐doped TiO 2 nanoparticles prepared by microwave‐assisted hydrothermal method
- Author
-
Cátia Liane Ücker, Suelen R. Almeida, Marcelo L. Vitale, Fábio C. Riemke, Mateus M. Ferrer, Eduardo C. Moreira, Cristiane W. Raubach, and Sergio Cava
- Subjects
Marketing ,Materials Chemistry ,Ceramics and Composites ,Condensed Matter Physics - Published
- 2022
- Full Text
- View/download PDF
6. Crystal structure, dielectric properties, and optical bandgap control in KNbO 3 –BiMnO 3 ceramics
- Author
-
Cristina Pascual‐Gonzalez, Carolina Elicker, Mario L. Moreira, Sergio Cava, Iasmi Sterianou, Dawei Wang, and Antonio Feteira
- Subjects
Materials Chemistry ,Ceramics and Composites - Abstract
(1 − x)KNbO3–xBiMnO3 (0 ≤ x ≤ 0.25) ceramics were prepared by the solid‐state reaction method. An X‐ray diffraction analysis combined with Raman spectroscopy showed the co‐solubility of Bi and Mn in the orthorhombic structure to be less than 5% BiMnO3. Orthorhombic and pseudocubic symmetries coexist in the 0.05 ≤ x ≤ 0.15 region, coinciding with a bimodal grain size distribution. This coexistence of crystal symmetries is further corroborated by several anomalies in the dielectric behavior, which can be ascribed to structural phase transitions. For x ≥ 0.20, only one dielectric anomaly is detected around 100°C, which is commensurate with in situ Raman spectroscopy analysis. This work also shows that Bi/Mn co‐doping can be employed to tailor the bandgap of KNbO3, which narrows continuously with increasing x, resulting in ∼1‐eV narrowing for single‐phase x = 0.25. This may offer the possibility to employ this ferroic material in photoresponsive technologies. more...
- Published
- 2022
- Full Text
- View/download PDF
7. Rehabilitation for <scp>post‐COVID</scp> ‐19 condition through a supervised exercise intervention: A randomized controlled trial
- Author
-
Amaya Jimeno‐Almazán, Francisco Franco‐López, Ángel Buendía‐Romero, Alejandro Martínez‐Cava, José Antonio Sánchez‐Agar, Bernardino J. Sánchez‐Alcaraz Martínez, Javier Courel‐Ibáñez, and Jesús G. Pallarés more...
- Subjects
Quality of Life ,Humans ,COVID-19 ,Resistance Training ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Muscle Strength ,Exercise Therapy - Abstract
The aim of the study was to compare the outcomes of patients with post-COVID-19 condition undergoing supervised therapeutic exercise intervention or following the self-management WHO (World Health Organization) rehabilitation leaflet.A randomized controlled trial was carried out that included 39 participants with post-COVID-19 condition who had a chronic symptomatic phase lasting12 weeks. Comprehensive medical screening, patient-reported symptoms, and cardiorespiratory fitness and muscular strength were assessed. Patients were randomly assigned to a tailored multicomponent exercise program based on concurrent training for 8 weeks (two supervised sessions per week comprised resistance training combined with aerobic training [moderate intensity variable training], plus a third day of monitored light intensity continuous training), or to a control group which followed the WHO guidelines for rehabilitation after COVID-19.After follow-up, there were changes in physical outcomes in both groups, however, the magnitude of the change pre-post intervention favored the exercise group in cardiovascular and strength markers: VOCompared to current WHO recommendations, a supervised, tailored concurrent training at low and moderate intensity for both resistance and endurance training is a more effective, safe, and well-tolerated intervention in post-COVID-19 conditions. more...
- Published
- 2022
- Full Text
- View/download PDF
8. Fast synthesis of NaNbO3 nanoparticles with high photocatalytic activity for degradation of organic dyes
- Author
-
Daiane Fernandes, Mateus M. Ferrer, Cristiane W. Raubach, Mario L. Moreira, Pedro L. G. Jardim, Eduardo Ceretta Moreira, Carlos F. O. Graeff, and Sergio S. Cava
- Subjects
Materials Chemistry ,Ceramics and Composites - Published
- 2022
- Full Text
- View/download PDF
9. A Bayesian reliability analysis exploring the effect of scheduled maintenance on wind turbine time to failure
- Author
-
Anderson, Fraser, primary, Dawid, Rafael, additional, McMillan, David, additional, and García‐Cava, David, additional
- Published
- 2023
- Full Text
- View/download PDF
10. Chemical Profiles of the Oxides on Tantalum in State of the Art Superconducting Circuits
- Author
-
McLellan, Russell A., primary, Dutta, Aveek, additional, Zhou, Chenyu, additional, Jia, Yichen, additional, Weiland, Conan, additional, Gui, Xin, additional, Place, Alexander P. M., additional, Crowley, Kevin D., additional, Le, Xuan Hoang, additional, Madhavan, Trisha, additional, Gang, Youqi, additional, Baker, Lukas, additional, Head, Ashley R., additional, Waluyo, Iradwikanari, additional, Li, Ruoshui, additional, Kisslinger, Kim, additional, Hunt, Adrian, additional, Jarrige, Ignace, additional, Lyon, Stephen A., additional, Barbour, Andi M., additional, Cava, Robert J., additional, Houck, Andrew A., additional, Hulbert, Steven L., additional, Liu, Mingzhao, additional, Walter, Andrew L., additional, and de Leon, Nathalie P., additional more...
- Published
- 2023
- Full Text
- View/download PDF
11. The effect of air pollution on COVID‐19 severity in a sample of patients with multiple sclerosis
- Author
-
Bergamaschi, Roberto, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Pisoni, Enrico, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Gianmarco Abbadessa, Umberto Aguglia, Lia Allegorico, Rossi Beatrice Maria Allegri, Anastasia Alteno, Maria Pia Amato, Pietro Annovazzi, Carlo Antozzi, Lucia Appendino, Sebastiano Arena, Viola Baione, Roberto Balgera, Valeria Barcella, Damiano Baroncini, Caterina Barrilà, Mario A Battaglia, Alessandra Bellacosa, Gianmarco Bellucci, Roberto Bergamaschi, Valeria Bergamaschi, Daiana Bezzini, Beatrice Biolzi, Alvino Bisecco, Simona Bonavita, Giovanna Borriello, Chiara Bosa, Antonio Bosco, Francesca Bovis, Marco Bozzali, Laura Brambilla, Morra Vincenzo Brescia, Giampaolo Brichetto, Maria Buccafusca, Elisabetta Bucciantini, Sebastiano Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano Calabrese, Francesca Calabria, Francesca Caleri, Federico Camilli, Luisa Maria Caniatti, Roberto Cantello, Marco Capobianco, Ruggero Capra, Rocco Capuano, Luca Carmisciano, Patrizia Carta, Paola Cavalla, Maria Grazia Celani, Maria Cellerino, Raffaella Cerqua, Clara Chisari, Raffaella Clerici, Marinella Clerico, Eleonora Cocco, Gaia Cola, Giancarlo Comi, Paolo Confalonieri, Antonella Conte, Marta Zaffira Conti, Christian Cordano, Susanna Cordera, Cinzia Cordioli, Francesco Corea, Claudio Correale, Salvatore Cottone, Francesco Crescenzo, Erica Curti, Alessandro d'Ambrosio, Emanuele D'Amico, Maura Chiara Danni, Alessia d'Arma, Vincenzo Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Rossi, Nicola De Stefano, Cava Marco Della, Mario di Napoli, Alessia Di Sapio, Renato Docimo, Anna Dutto, Luana Evangelista, Salvatore Fanara, Diana Ferraro, Maria Teresa Ferrò, Massimo Filippi, Cristina Fioretti, Mario Fratta, Jessica Frau, Marzia Fronza, Roberto Furlan, Alberto Gajofatto, Antonio Gallo, Paolo Gallo, Claudio Gasperini, Anna Ghazaryan, Bruno Giometto, Francesca Gobbin, Flora Govone, Franco Granella, Erica Grange, Maria Grazia Grasso, Angelica Guareschi, Clara Guaschino, Simone Guerrieri, Donata Guidetti, Pietro Iaffaldano, Antonio Ianniello, Luigi Iasevoli, Paolo Immovilli, Daniele Imperiale, Maria Teresa Infante, Matilde Inglese, Rosa Iodice, Aniello Iovino, Giovanna Konrad, Doriana Landi, Roberta Lanzillo, Caterina Lapucci, Luigi Lavorgna, Maria Rita L'Episcopo, Serena Leva, Giuseppe Liberatore, Re Marianna Lo, Marco Longoni, Leonardo Lopiano, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Davide Maimone, Maria Malentacchi, Giulia Mallucci, Simona Malucchi, Chiara Rosa Mancinelli, Luca Mancinelli, Paolo Manganotti, Giorgia Teresa Maniscalco, Vittorio Mantero, Sabrina Marangoni, Damiano Marastoni, Girolama Alessandra Marfia, Fabiana Marinelli, Alessandro Marti, Boneschi Filippo Martinelli, Zoli Federco Masserano, Francesca Matta, Laura Mendozzi, Giuseppe Meucci, Silvia Miante, Giuseppina Miele, Eva Milano, Massimiliano Mirabella, Rosanna Missione, Marcello Moccia, Lucia Moiola, Sara Montepietra, Margherita MontiBragadin, Federico Montini, Roberta Motta, Raffaele Nardone, Carolina Gabri Nicoletti, Eduardo Nobile-Orazio, Agostino Nozzolillo, Marco Onofrj, Riccardo Orlandi, Anna Palmieri, Damiano Paolicelli, Livia Pasquali, Luisa Pastò, Francesco Patti, Elisabetta Pedrazzoli, Paola Perini, Ilaria Pesci, Maria Petracca, Alfredo Petrone, Carlo Piantadosi, Anna M Pietroboni, Federica Pinardi, Marta Ponzano, Emilio Portaccio, Mattia Pozzato, Carlo Pozzilli, Luca Prosperini, Alessandra Protti, Marta Radaelli, Paolo Ragonese, Sarah Rasia, Sabrina Realmuto, Anna Repice, Eleonora Rigoni, Maria Teresa Rilla, Francesca Rinaldi, Calogero Marcello Romano, Marco Ronzoni, Marco Rovaris, Francesca Ruscica, Loredana Sabattini, Giuseppe Salemi, Marco Salvetti, Lorenzo Saraceno, Alessia Sartori, Arianna Sartori, Elvira Sbragia, Cinzia Scandellari, Giuditta Ilaria Scarano, Valentina Scarano, Irene Schiavetti, Maria Sessa, Caterina Sgarito, Grazia Sibilia, Gabriele Siciliano, Alessio Signori, Elisabetta Signoriello, Leonardo Sinisi, Francesca Sireci, Patrizia Sola, Claudio Solaro, Maria Pia Sormani, Stefano Sotgiu, Maddalena Sparaco, Maria Laura Stromillo, Silvia Strumia, Emanuela Laura Susani, Giulietta Tabiadon, Francesco Teatini, Gioacchino Tedeschi, Valentina Tomassini, Simone Tonietti, Clerici Valentina Torri, Carla Tortorella, Simona Toscano, Rocco Totaro, Maria Trojano, Maria Trotta, Gabriella Turano, Monica Ulivelli, Manzo Valentino, Giovanna Vaula, Domizia Vecchio, Marco Vercellino, Elena Pinuccia Verrengia, Marika Vianello, Eleonora Virgilio, Francesca Vitetta, Stefano Vollaro, Mauro Zaffaroni, Mauro Zampolini, Ignazio Roberto Zarbo, Antonio Zito, Luigi Zuliani, Bergamaschi, R, Ponzano, M, Schiavetti, I, Carmisciano, L, Cordioli, C, Filippi, M, Radaelli, M, Immovilli, P, Capobianco, M, De Rossi, N, Brichetto, G, Cocco, E, Scandellari, C, Cavalla, P, Pesci, I, Zito, A, Confalonieri, P, Marfia, Ga, Perini, P, Inglese, M, Trojano, M, Brescia Morra, V, Pisoni, E, Tedeschi, G, Comi, G, Battaglia, Ma, Patti, F, Salvetti, M, Sormani, Mp, Abbadessa, Gianmarco, Umberto, Aguglia, Lia, Allegorico, Rossi Beatrice Maria Allegri, Anastasia, Alteno, Maria Pia Amato, Pietro, Annovazzi, Carlo, Antozzi, Lucia, Appendino, Sebastiano, Arena, Viola, Baione, Roberto, Balgera, Valeria, Barcella, Damiano, Baroncini, Caterina, Barrilà, Mario, A Battaglia, Alessandra, Bellacosa, Gianmarco, Bellucci, Roberto, Bergamaschi, Valeria, Bergamaschi, Daiana, Bezzini, Beatrice, Biolzi, Bisecco, Alvino, Bonavita, Simona, Giovanna, Borriello, Chiara, Bosa, Bosco, Antonio, Francesca, Bovi, Marco, Bozzali, Laura, Brambilla, Morra Vincenzo Brescia, Giampaolo, Brichetto, Maria, Buccafusca, Elisabetta, Bucciantini, Sebastiano, Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano, Calabrese, Francesca, Calabria, Francesca, Caleri, Federico, Camilli, Luisa Maria Caniatti, Roberto, Cantello, Marco, Capobianco, Ruggero, Capra, Capuano, Rocco, Luca, Carmisciano, Patrizia, Carta, Paola, Cavalla, Maria Grazia Celani, Maria, Cellerino, Raffaella, Cerqua, Clara, Chisari, Raffaella, Clerici, Marinella, Clerico, Eleonora, Cocco, Gaia, Cola, Giancarlo, Comi, Paolo, Confalonieri, Antonella, Conte, Marta Zaffira Conti, Christian, Cordano, Susanna, Cordera, Cinzia, Cordioli, Corea, Francesco, Claudio, Correale, Salvatore, Cottone, Francesco, Crescenzo, Erica, Curti, Alessandro, D'Ambrosio, Emanuele, D'Amico, Maura Chiara Danni, Alessia, D'Arma, Vincenzo, Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Rossi, Nicola De Stefano, Cava Marco Della, Mario di Napoli, Alessia Di Sapio, Docimo, Renato, Anna, Dutto, Luana, Evangelista, Salvatore, Fanara, Diana, Ferraro, Maria Teresa Ferrò, Massimo, Filippi, Cristina, Fioretti, Fratta, Mario, Jessica, Frau, Marzia, Fronza, Roberto, Furlan, Alberto, Gajofatto, Gallo, Antonio, Paolo, Gallo, Claudio, Gasperini, Anna, Ghazaryan, Bruno, Giometto, Francesca, Gobbin, Flora, Govone, Franco, Granella, Erica, Grange, Maria Grazia Grasso, Angelica, Guareschi, Clara, Guaschino, Simone, Guerrieri, Donata, Guidetti, Pietro, Iaffaldano, Antonio, Ianniello, Luigi, Iasevoli, Paolo, Immovilli, Daniele, Imperiale, Maria Teresa Infante, Matilde, Inglese, Rosa, Iodice, Aniello, Iovino, Giovanna, Konrad, Doriana, Landi, Roberta, Lanzillo, Caterina, Lapucci, Luigi, Lavorgna, Maria Rita L'Episcopo, Serena, Leva, Giuseppe, Liberatore, Re Marianna Lo, Marco, Longoni, Leonardo, Lopiano, Lorena, Lorefice, Matteo, Lucchini, Lus, Giacomo, Davide, Maimone, Maria, Malentacchi, Giulia, Mallucci, Simona, Malucchi, Chiara Rosa Mancinelli, Luca, Mancinelli, Paolo, Manganotti, Giorgia Teresa Maniscalco, Vittorio, Mantero, Sabrina, Marangoni, Damiano, Marastoni, Girolama Alessandra Marfia, Fabiana, Marinelli, Alessandro, Marti, Boneschi Filippo Martinelli, Zoli Federco Masserano, Francesca, Matta, Laura, Mendozzi, Giuseppe, Meucci, Silvia, Miante, Miele, Giuseppina, Eva, Milano, Massimiliano, Mirabella, Missione, Rosanna, Marcello, Moccia, Lucia, Moiola, Sara, Montepietra, Margherita, Montibragadin, Federico, Montini, Roberta, Motta, Raffaele, Nardone, Carolina Gabri Nicoletti, Eduardo, Nobile-Orazio, Agostino, Nozzolillo, Marco, Onofrj, Riccardo, Orlandi, Palmieri, Anna, Damiano, Paolicelli, Livia, Pasquali, Luisa, Pastò, Francesco, Patti, Elisabetta, Pedrazzoli, Paola, Perini, Ilaria, Pesci, Maria, Petracca, Alfredo, Petrone, Carlo, Piantadosi, Anna, M Pietroboni, Federica, Pinardi, Marta, Ponzano, Emilio, Portaccio, Mattia, Pozzato, Carlo, Pozzilli, Luca, Prosperini, Alessandra, Protti, Marta, Radaelli, Paolo, Ragonese, Sarah, Rasia, Sabrina, Realmuto, Anna, Repice, Eleonora, Rigoni, Maria Teresa Rilla, Francesca, Rinaldi, Calogero Marcello Romano, Marco, Ronzoni, Marco, Rovari, Francesca, Ruscica, Loredana, Sabattini, Giuseppe, Salemi, Marco, Salvetti, Lorenzo, Saraceno, Alessia, Sartori, Arianna, Sartori, Elvira, Sbragia, Cinzia, Scandellari, Giuditta Ilaria Scarano, Valentina, Scarano, Irene, Schiavetti, Maria, Sessa, Caterina, Sgarito, Grazia, Sibilia, Gabriele, Siciliano, Alessio, Signori, Signoriello, Elisabetta, Leonardo, Sinisi, Francesca, Sireci, Patrizia, Sola, Claudio, Solaro, Maria Pia Sormani, Stefano, Sotgiu, Sparaco, Maddalena, Maria Laura Stromillo, Silvia, Strumia, Emanuela Laura Susani, Giulietta, Tabiadon, Francesco, Teatini, Tedeschi, Gioacchino, Valentina, Tomassini, Simone, Tonietti, Clerici Valentina Torri, Carla, Tortorella, Simona, Toscano, Rocco, Totaro, Maria, Trojano, Trotta, Maria Consiglia, Gabriella, Turano, Monica, Ulivelli, Manzo, Valentino, Giovanna, Vaula, Domizia, Vecchio, Marco, Vercellino, Elena Pinuccia Verrengia, Marika, Vianello, Eleonora, Virgilio, Francesca, Vitetta, Stefano, Vollaro, Mauro, Zaffaroni, Mauro, Zampolini, Ignazio Roberto Zarbo, Zito, Guido Antonio, Bergamaschi, R., Ponzano, M., Schiavetti, I., Carmisciano, L., Cordioli, C., Filippi, M., Radaelli, M., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Cocco, E., Scandellari, C., Cavalla, P., Pesci, I., Zito, A., Confalonieri, P., Marfia, G. A., Perini, P., Inglese, M., Trojano, M., Brescia Morra, V., Pisoni, E., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Bergamaschi, Roberto, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Pisoni, Enrico, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria, Pia, Gianmarco, Abbadessa, Alvino, Bisecco, Simona, Bonavita, Antonio, Bosco, Rocco, Capuano, Francesco, Corea, Renato, Docimo, Mario, Fratta, Antonio, Gallo, Iodice, Rosa, Iovino, Aniello, Lanzillo, Roberta, Giacomo, Lu, Giuseppina, Miele, Rosanna, Missione, Moccia, Marcello, Anna, Palmieri, Elisabetta, Signoriello, Maddalena, Sparaco, Gioacchino, Tedeschi, Maria, Trotta, Antonio, Zito, and Luigi, Zuliani more...
- Subjects
air pollution ,coronavirus ,multiple sclerosis ,medicine.medical_specialty ,Multivariate analysis ,Coronavirus disease 2019 (COVID-19) ,Clinical Sciences ,Air pollution ,Sample (statistics) ,Neurodegenerative ,Settore MED/26 ,medicine.disease_cause ,Autoimmune Disease ,law.invention ,Sustainable Cities and Communities ,Clinical Research ,law ,Humans ,Medicine ,Climate-Related Exposures and Conditions ,Neurology & Neurosurgery ,MuSC-19 study group ,SARS-CoV-2 ,business.industry ,Multiple sclerosis ,Neurosciences ,COVID-19 ,Retrospective cohort study ,Original Articles ,medicine.disease ,Intensive care unit ,Particulate Matter ,Air Pollution ,Multiple Sclerosis ,Brain Disorders ,coronaviru ,Settore MED/26 - NEUROLOGIA ,Good Health and Well Being ,Neurology ,multiple sclerosi ,Emergency medicine ,Original Article ,Neurology (clinical) ,Ordered logit ,business ,Human - Abstract
Background and purpose Some studies have shown that air pollution, often assessed by thin particulate matter with diameter below 2.5 µg/m3 (PM2.5), may contribute to severe COVID‐19 courses, as well as play a role in the onset and evolution of multiple sclerosis (MS). However, the impact of air pollution on COVID‐19 has never been explored specifically amongst patients with MS (PwMS). This retrospective observational study aims to explore associations between PM2.5 and COVID‐19 severity amongst PwMS. Methods Data were retrieved from an Italian web‐based platform (MuSC‐19) which includes PwMS with COVID‐19. PM2.5 2016–2018 average concentrations were provided by the Copernicus Atmospheric Monitoring Service. Italian patients inserted in the platform from 15 January 2020 to 9 April 2021 with a COVID‐19 positive test were included. Ordered logistic regression models were used to study associations between PM2.5 and COVID‐19 severity. Results In all, 1087 patients, of whom 13% required hospitalization and 2% were admitted to an intensive care unit or died, were included. Based on the multivariate analysis, higher concentrations of PM2.5 increased the risk of worse COVID‐19 course (odds ratio 1.90; p = 0.009). Conclusions Even if several other factors explain the unfavourable course of COVID‐19 in PwMS, the role of air pollutants must be considered and further investigated., Air pollution, often assessed by particulate matter with diameter below 2.5 µg/m3, may contribute to severe COVID‐19 courses. 1087 patients were included, of whom 13% required hospitalization and 2% were admitted to an intensive care unit or died. Even if several other factors explain the unfavourable course of COVID‐19 in patients with multiple sclerosis, the role of air pollutants must be considered and further investigated. more...
- Published
- 2021
- Full Text
- View/download PDF
12. Signs and symptoms of COVID-19 in patients with multiple sclerosis
- Author
-
Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), Mirabella M. (ORCID:0000-0002-7783-114X), Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), and Mirabella M. (ORCID:0000-0002-7783-114X) more...
- Abstract
Background and purpose Clinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation. Method Logistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number. Results From March 2020 to November 2021, data were collected from 1354 MS patients with confirmed infection of COVID-19. Ageusia and anosmia was less frequent in older people (odds ratio [OR] 0.98; p = 0.005) and more in smoker patients (OR 1.39; p = 0.049). Smoke was also associated with an incremental number of symptoms (OR 1.24; p = 0.031), substance abuse (drugs or alcohol), conjunctivitis and rash (OR 5.20; p = 0.042) and the presence of at least one comorbidity with shortness of breath, tachycardia or chest pain (OR 1.24; p = 0.008). Some disease-modifying therapies were associated with greater frequencies of certain COVID-19 symptoms (association between anti-CD20 therapies and increment in the number of concomitant symptoms: OR 1.29; p = 0.05). Differences in frequencies between the three waves were found for flu-like symptoms (G1, p = 0.024), joint or muscle pain (G2, p = 0.013) and ageusia and anosmia (G5, p < 0.001). All cases should be referred to variants up to Delta. Conclusion Several factors along with the choice of specific therapeutic approaches might have a different impact on the occurrence of some COVID-19 symptoms. more...
- Published
- 2022
13. SHARDS: stellar populations and star formation histories of a mass-selected sample of 0.65 < z < 1.1 galaxies
- Author
-
Pérez González, Pablo Guillermo, Cardiel López, Nicolás, Cava, Antonio, Barro, Guillermo, Gallego Maestro, Jesús, Pérez González, Pablo Guillermo, Cardiel López, Nicolás, Cava, Antonio, Barro, Guillermo, and Gallego Maestro, Jesús more...
- Abstract
This article has been accepted for publication in Monthly notices of the Royal Astronomical Society Journal © 2013 RAS. Published by Oxford University Press on behalf of the Royal Astronomical Society. All rights reserved. AH-C and AA-H acknowledge funding by the Universidad de Cantabria Augusto González Linares program. We acknowledge support from the Spanish Programa Nacional de Astronomía y Astrofísica under grants AYA2009-07723-E and AYA2009-10368. SHARDS has been funded by the Spanish MICINN/MINECO under the Consolider-Ingenio 2010 Program grant CSD2006-00070: First Science with the GTC. This work has made use of the Rainbow Cosmological Surveys Database, which is operated by the Universidad Complutense de Madrid (UCM). Based on observations made with the GTC, installed at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias, in the island of La Palma. We thank all the GTC Staff for their support and enthusiasm with the SHARDS project, and we would like to especially acknowledge the help from Antonio Cabrera and Rene Rutten. We also thank the anonymous referee for their useful comments that helped to improve this paper., We report on results from the analysis of a stellar mass-selected (log (M-*/M-circle dot) >= 9.0) sample of 1644 galaxies at 0.65 < z < 1.1 with ultradeep (m(AB) < 26.5) optical medium-band (R similar to 50) photometry from the Survey for High-z Absorption Red and Dead Sources (SHARDS). The spectral resolution of SHARDS allows us to consistently measure the strength of the 4000 A spectral break [D-n(4000), an excellent age indicator for the stellar populations of quiescent galaxies] for all galaxies at z similar to 0.9 down to log (M-*/M-circle dot) similar to 9. The D-n(4000) index cannot be resolved from broad-band photometry, and measurements from optical spectroscopic surveys are typically limited to galaxies at least 10 times more massive. When combined with the rest-frame U - V colour, (U - V)(r), D-n(4000) provides a powerful diagnostic of the extinction affecting the stellar population that is relatively insensitive to degeneracies with age, metallicity or star formation history. We use this novel approach to estimate de-reddened colours and light-weighted stellar ages for individual sources. We explore the relationships linking stellar mass, (U - V)(r), and D-n(4000) for the sources in the sample, and compare them to those found in local galaxies. The main results are: (a) both D-n(4000) and (U - V)(r) correlate with M-*. The dispersion in D-n(4000) values at a given M-* increases with M-*, while the dispersion for (U - V)(r) decreases due to the higher average extinction prevalent in massive star-forming galaxies. (b) For massive galaxies, we find a smooth transition between the blue cloud and red sequence in the intrinsic U - V colour, in contrast with other recent results. (c) At a fixed stellar age, we find a positive correlation between extinction and stellar mass. (d) The fraction of sources with declining or halted star formation increases steeply with the stellar mass, from similar to 5 per cent at log (M-*/M-circle dot) = 9.0-9.5 to similar to 80 p, Universidad de Cantabria Augusto Gonzalez Linares program, Spanish Programa Nacional de Astronomia y Astrofisica, Spanish MICINN/MINECO under the Consolider-Ingenio Program, Depto. de Física de la Tierra y Astrofísica, Fac. de Ciencias Físicas, TRUE, pub more...
- Published
- 2023
14. A Bayesian hierarchical assessment of night shift working for offshore wind farms
- Author
-
Anderson, Fraser, primary, McMillan, David, additional, Dawid, Rafael, additional, and Garcia Cava, David, additional
- Published
- 2023
- Full Text
- View/download PDF
15. Challenges and directions for open ecosystems biodiversity restoration: An overview of the techniques applied for Cerrado
- Author
-
Pilon, Natashi A. L., primary, Campos, Bruna H., additional, Durigan, Giselda, additional, Cava, Mário G. B., additional, Rowland, Lucy, additional, Schmidt, Isabel, additional, Sampaio, Alexandre, additional, and Oliveira, Rafael S., additional more...
- Published
- 2023
- Full Text
- View/download PDF
16. Topical sevoflurane corneal toxicity: in vitro study
- Author
-
Raquel Maroto Cejudo, Denisse Michelle Espinosa Encalada, Carlos Cava Valenciano, Mónica Gómez‐ Juarez Sango, Maria Gomez Picazo, and Fernando Andrés Pretel
- Subjects
Ophthalmology ,General Medicine - Published
- 2022
- Full Text
- View/download PDF
17. Topical sevoflurane ocular toxicity: in vivo study
- Author
-
Denisse Michelle Espinosa Encalada, Raquel Maroto Cejudo, Carlos Cava Valenciano, Mónica Gómez‐Juarez Sango, Victoria Adámoli Vidal, and Fernando Andrés Pretel
- Subjects
Ophthalmology ,General Medicine - Published
- 2022
- Full Text
- View/download PDF
18. Author response for 'A Bayesian hierarchical assessment of night shift working for offshore wind farms'
- Author
-
null Fraser Anderson, null David McMillan, null Rafael Dawid, and null David Garcia Cava
- Published
- 2022
- Full Text
- View/download PDF
19. Enhancement of the Magnetoresistance in the Mobility‐Engineered Compensated Metal Pt 5 P 2
- Author
-
Mayo, Alex H., primary, Takahashi, Hidefumi, additional, Ishiwata, Shintaro, additional, Górnicka, Karolina, additional, Winiarski, Michał J., additional, Jaroszynski, Jan, additional, Cava, Robert J., additional, Xie, Weiwei, additional, and Klimczuk, Tomasz, additional more...
- Published
- 2022
- Full Text
- View/download PDF
20. Photocatalytic performance of Al and Nb‐doped TiO 2 nanoparticles prepared by microwave‐assisted hydrothermal method
- Author
-
Ücker, Cátia Liane, primary, Almeida, Suelen R., additional, Vitale, Marcelo L., additional, Riemke, Fábio C., additional, Ferrer, Mateus M., additional, Moreira, Eduardo C., additional, Raubach, Cristiane W., additional, and Cava, Sergio, additional more...
- Published
- 2022
- Full Text
- View/download PDF
21. Topical sevoflurane corneal toxicity: in vitro study
- Author
-
Cejudo, Raquel Maroto, primary, Encalada, Denisse Michelle Espinosa, additional, Valenciano, Carlos Cava, additional, Juarez Sango, Mónica Gómez‐, additional, Picazo, Maria Gomez, additional, and Pretel, Fernando Andrés, additional more...
- Published
- 2022
- Full Text
- View/download PDF
22. Topical sevoflurane ocular toxicity: in vivo study
- Author
-
Encalada, Denisse Michelle Espinosa, primary, Cejudo, Raquel Maroto, additional, Valenciano, Carlos Cava, additional, Sango, Mónica Gómez‐Juarez, additional, Vidal, Victoria Adámoli, additional, and Pretel, Fernando Andrés, additional more...
- Published
- 2022
- Full Text
- View/download PDF
23. The Distributional Effects of Monetary Policy: Evidence from Local Housing Markets in Australia
- Author
-
Gianni La Cava and Calvin He
- Subjects
Economics and Econometrics ,Monetary policy ,Economics ,Monetary economics - Published
- 2021
- Full Text
- View/download PDF
24. <scp>d</scp> ‐canavanine affects peptidoglycan structure, morphogenesis and fitness in Rhizobiales
- Author
-
Felipe Cava, Alena Aliashkevich, Matthew Howell, and Pamela J. B. Brown
- Subjects
Cell division ,Peptidoglycan ,Microbiology ,Bacterial cell structure ,Cell wall ,Canavanine ,03 medical and health sciences ,chemistry.chemical_compound ,Bacterial Proteins ,Cell Wall ,Morphogenesis ,Ecology, Evolution, Behavior and Systematics ,Alphaproteobacteria ,030304 developmental biology ,0303 health sciences ,Sinorhizobium meliloti ,biology ,030306 microbiology ,fungi ,food and beverages ,biology.organism_classification ,Pseudomonas putida ,Rhizobiales ,Cell biology ,Mikrobiologi ,chemistry - Abstract
The bacterial cell wall is made of peptidoglycan (PG), a polymer that is essential for maintenance of cell shape and survival. Many bacteria alter their PG chemistry as a strategy to adapt their cell wall to external challenges. Therefore, identifying these environmental cues is important to better understand the interplay between microbes and their habitat. Here we used the soil bacterium Pseudomonas putida to uncover cell wall modulators from plant extracts and found canavanine (CAN), a non-proteinogenic amino acid. We demonstrated that cell wall chemical editing by CAN is licensed by P. putida BSAR, a broad-spectrum racemase which catalyzes production of DL-CAN from L-CAN, which is produced by many legumes. Importantly, D-CAN diffuses to the extracellular milieu thereby having a potential impact on other organisms inhabiting the same niche. Our results show that D-CAN alters dramatically the PG structure of Rhizobiales (e.g. Agrobacterium tumefaciens, Sinorhizobium meliloti), impairing PG crosslinkage and cell division. Using A. tumefaciens we demonstrated that the detrimental effect of D-CAN is suppressed by a single amino acid substitution in the cell division PG transpeptidase penicillin binding protein 3a. Collectively, this work highlights the role of amino acid racemization in cell wall chemical editing and fitness. This article is protected by copyright. All rights reserved. more...
- Published
- 2021
- Full Text
- View/download PDF
25. Crystal structure, dielectric properties, and optical bandgap control in KNbO 3 –BiMnO 3 ceramics
- Author
-
Pascual‐Gonzalez, Cristina, primary, Elicker, Carolina, additional, Moreira, Mario L., additional, Cava, Sergio, additional, Sterianou, Iasmi, additional, Wang, Dawei, additional, and Feteira, Antonio, additional more...
- Published
- 2022
- Full Text
- View/download PDF
26. Rehabilitation for post‐COVID ‐19 condition through a supervised exercise intervention: A randomized controlled trial
- Author
-
Jimeno‐Almazán, Amaya, primary, Franco‐López, Francisco, additional, Buendía‐Romero, Ángel, additional, Martínez‐Cava, Alejandro, additional, Sánchez‐Agar, José Antonio, additional, Sánchez‐Alcaraz Martínez, Bernardino J., additional, Courel‐Ibáñez, Javier, additional, and Pallarés, Jesús G., additional more...
- Published
- 2022
- Full Text
- View/download PDF
27. Fast synthesis of NaNbO3 nanoparticles with high photocatalytic activity for degradation of organic dyes
- Author
-
Fernandes, Daiane, primary, Ferrer, Mateus M., additional, Raubach, Cristiane W., additional, Moreira, Mario L., additional, Jardim, Pedro L. G., additional, Moreira, Eduardo Ceretta, additional, Graeff, Carlos F. O., additional, and Cava, Sergio S., additional more...
- Published
- 2022
- Full Text
- View/download PDF
28. Effect of high‐pressure treatment and storage temperature on top‐quality (Montanera) Iberian dry‐cured pork sausages (chorizo)
- Author
-
A. Gómez-Quintana, A. Trejo, Jesús García-Parra, Ramón Cava, M.J. Martín, and M.R. Ramírez
- Subjects
Materials science ,Swine ,030309 nutrition & dietetics ,Raw material ,Protein oxidation ,Sensory analysis ,03 medical and health sciences ,0404 agricultural biotechnology ,Food Preservation ,Hydrostatic Pressure ,Animals ,Humans ,Food science ,Dry cured ,Pork sausage ,0303 health sciences ,Temperature ,food and beverages ,04 agricultural and veterinary sciences ,040401 food science ,Meat Products ,High pressure ,Fermentation ,Pork Meat ,Refrigeration temperature ,Food Science ,Mesophile - Abstract
The stability after hydrostatic high pressure (HHP) (600 MPa/8 min/10 °C) and 180 days of storage at 4 and 20 °C was evaluated on Iberian dry-cured pork sausages (chorizo) packaged sliced or as half-pieces from pigs raised outdoors. Microbiological, physical-chemical, oxidative, and sensory changes were analyzed. The evolution of mesophilic aerobic and molds and yeasts counts was different in the half and sliced packaged pork sausages after processing and during storage. Sliced and half-packaged pork sausages had instrumental color stability after HHP and during storage. TBA-RS values were quite stable in both products. Protein oxidation values of pork sausage in half-products were increased by at 20 °C. In sliced pork sausage, both HPP and 20 °C storage favored the development of protein oxidation at the end of storage. In the sensory analysis, the sliced product developed more rancidity than the half-pieces during the storage. Therefore, the storage temperature has great importance for the preservation of dry-cured pork sausages, the increases of protein oxidation, and rancidity could reduce the shelf-life at these conditions. The presentation of the product is also relevant when HHP is applied, and this would also compromise the stability of the product when it is stored at room temperature. PRACTICAL APPLICATION: Chorizo is a traditional dry-fermented pork sausage that is generally considered to be microbiologically safe. However, the initial contamination of the raw materials, and some processes, such as the slicing or packaging, can compromise the safety of these products. Additionally, packaged dry-cured sausages require long shelf-life, and although they are normally stored at refrigeration temperature; sometimes, they are preserved at room temperature. The application of hydrostatic high pressure could increase the safety of dry-cured meat products even when they are stored at room temperature. Initial characteristics of each type of pork sausage could determine their technological behavior during processing or during storage under different conditions. more...
- Published
- 2021
- Full Text
- View/download PDF
29. Rio de Janeiro and other palaeodrainages evidenced by the genetic structure of an Atlantic Forest catfish
- Author
-
John C. Avise, Claudia Russo, Cristiano Lazoski, Thaís de Assis Volpi, Henrique Lazzarotto, Anderson Vilasboa, Andrey Tatarenkov, Antonio M. Solé-Cava, Sergio M. Q. Lima, and Waldir M. Berbel-Filho
- Subjects
Phylogeography ,Geography ,Ecology ,biology ,Genetic structure ,Atlantic forest ,biology.organism_classification ,Trichomycteridae ,Ecology, Evolution, Behavior and Systematics ,Catfish - Published
- 2021
- Full Text
- View/download PDF
30. Comparative efficacy and safety of prostatic urethral lift vs prostatic artery embolization for benign prostatic hyperplasia: a systematic review and network meta‐analysis
- Author
-
Lucas‐Cava, Vanesa, primary, Sánchez‐Margallo, Francisco Miguel, additional, Insausti‐Gorbea, Iñigo, additional, and Sun, Fei, additional
- Published
- 2022
- Full Text
- View/download PDF
31. Synthesis and characterization of poly(vinyl alcohol)/chondroitin sulfate composite hydrogels containing strontium‐doped hydroxyapatite as promising biomaterials
- Author
-
André R. Fajardo, Lisiane Diehl, Sergio Cava, Guillermo Grazioli, Adriana Fernandes da Silva, Rafael R. Moraes, Jaqueline F. de Souza, Manoel Damião Sousa-Neto, and Carla David
- Subjects
Vinyl alcohol ,Materials science ,Compressive Strength ,Scanning electron microscope ,0206 medical engineering ,Biomedical Engineering ,Biocompatible Materials ,macromolecular substances ,02 engineering and technology ,complex mixtures ,Biomaterials ,chemistry.chemical_compound ,Elastic Modulus ,medicine ,Chondroitin sulfate ,Porosity ,Chondroitin Sulfates ,technology, industry, and agriculture ,Metals and Alloys ,021001 nanoscience & nanotechnology ,020601 biomedical engineering ,Thermogravimetry ,Durapatite ,Compressive strength ,chemistry ,Chemical engineering ,Strontium ,ESTRÔNCIO ,Polyvinyl Alcohol ,Self-healing hydrogels ,Ceramics and Composites ,Swelling ,medicine.symptom ,0210 nano-technology - Abstract
Novel poly(vinyl alcohol)/chondroitin sulfate (PVA/CS) composite hydrogels containing hydroxyapatite (HA) or Sr-doped HA (HASr) particles were synthesized by a freeze/thaw method and characterized aiming towards biomedical applications. HA and HASr were synthesized by a wet-precipitation method and added to the composite hydrogels in fractions up to 15 wt%. Physical-chemical characterizations of particles and hydrogels included scanning electron microscopy, energy-dispersive spectroscopy, Fourier-transform infrared spectroscopy, X-ray diffraction, thermogravimetry, porosity, compressive strength/elastic modulus, swelling degree, and cell viability. Particles were irregular in shape and appeared to have narrow size variation. The thermal behavior of composite hydrogels was altered compared to the control (bare) hydrogel. All hydrogels exhibited high porosity. HA/HASr particles reduced total porosity without reducing pore size. The mechanical strength was improved as the fraction of HA or HASr was increased. HASr particles led to a faster water uptake but did not interfere with the total hydrogel swelling capacity. In cell viability essay, increased cell growth (above 120%) was observed in all groups including the control hydrogel, suggesting a bioactive effect. In conclusion, PVA/CS hydrogels containing HA or HASr particles were successfully synthesized and showed promising morphological, mechanical, and swelling properties, which are particularly required for scaffolding. more...
- Published
- 2020
- Full Text
- View/download PDF
32. The diversity of post‐fire regeneration strategies in the cerrado ground layer
- Author
-
Mário G. B. Cava, Alessandra Fidelis, Giselda Durigan, Natashi A. L. Pilon, William A. Hoffmann, Rodolfo C. R. Abreu, Universidade Estadual de Campinas (UNICAMP), Universidade Estadual Paulista (Unesp), North Carolina State University, Universidade Federal Rural do Rio de Janeiro, and Instituto Florestal more...
- Subjects
Ecology ,fire response ,below-ground bud bank ,neotropical savanna ,Plant community ,Plant Science ,Vegetation ,Biology ,fire-prone ecosystems ,fire ecology ,Disturbance (ecology) ,herbaceous species ,underground structures ,Resprouter ,Ruderal species ,functional traits ,Species richness ,Fire ecology ,Regeneration (ecology) ,Ecology, Evolution, Behavior and Systematics - Abstract
Made available in DSpace on 2020-12-12T01:32:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Disentangling species strategies that confer resilience to natural disturbances is key to conserving and restoring savanna ecosystems. Fire is a recurrent disturbance in savannas, and savanna vegetation is highly adapted to and often dependent on fire. However, although the woody component of tropical savannas is well studied, we still do not understand how ground-layer plant communities respond to fire, limiting conservation and management actions. We investigated the effects of prescribed fire on community structure and composition, and evaluated which traits are involved in plant community regeneration after fire in the cerrado ground layer. We assessed traits related to species persistence and colonization capacity after fire, including resprouter type, underground structure, fire-induced flowering, regeneration strategy and growth form. We searched for functional groups related to response to fire, to shed light on the main strategies of post-fire recovery among species in the ground layer. Fire changed ground-layer community structure and composition in the short term, leading to greater plant species richness, population densities and increasing bare soil, compared with unburned communities. Eight months after fire, species abundance did not differ from pre-disturbance values for 86% of the species, demonstrating the resilience of this layer to fire. Only one ruderal species was disadvantaged by fire and 13% of the species benefited. Rapid recovery of soil cover by native vegetation in burned areas was driven by species with high capacity to resprout and spread vegetatively. Recovery of the savanna ground-layer community, as a whole, resulted from a combination of different species traits. We summarized these traits into five large groups, encompassing key strategies involved in ground-layer regeneration after fire. Synthesis. Fire dramatically changes the ground layer of savanna vegetation in the short term, but the system is highly resilient, quickly recovering the pre-fire state. Recovery involves different strategies, which we categorized into five functional groups of plant species: grasses, seeders, bloomers, undergrounders and resprouters. Knowledge of these diverse strategies should be used as a tool to assess conservation and restoration status of fire-resilient ecosystems in the cerrado. Instituto de Biologia Universidade Estadual de Campinas (UNICAMP) Departamento de Ciência Florestal Universidade Estadual Paulista (UNESP) Department of Plant and Microbial Biology North Carolina State University Departamento de Ciências Ambientais Universidade Federal Rural do Rio de Janeiro Instituto de Biociências Lab of Vegetation Ecology Universidade Estadual Paulista (UNESP) Laboratório de Ecologia e Hidrologia Florestal Floresta Estadual de Assis Instituto Florestal Departamento de Ciência Florestal Universidade Estadual Paulista (UNESP) Instituto de Biociências Lab of Vegetation Ecology Universidade Estadual Paulista (UNESP) more...
- Published
- 2020
- Full Text
- View/download PDF
33. Savannas after afforestation: Assessment of herbaceous community responses to wildfire versus native tree planting
- Author
-
Giselda Durigan, Ricardo Augusto Gorne Viani, Mário G. B. Cava, Joseph W. Veldman, Thaís Mazzafera Haddad, Universidade de São Paulo (USP), Universidade Federal de São Carlos (UFSCar), Universidade Estadual Paulista (Unesp), Inst Florestal Estado Sao Paulo, and Texas A&M Univ more...
- Subjects
SAVANA ,Tree planting ,Cerrado ,old-growth grassland ,Forestry ,Herbaceous plant ,Pinus ,savanna restoration ,%22">Pinus ,Geography ,Fire protection ,Afforestation ,fire suppression ,Brazil ,Ecology, Evolution, Behavior and Systematics - Abstract
Made available in DSpace on 2020-12-10T20:06:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-30 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) U.S. Department of Agriculture, National Institute of Food and Agriculture U.S. National Science Foundation Afforestation and fire exclusion are pervasive threats to tropical savannas. In Brazil, laws limiting prescribed burning hinder the study of fire in the restoration of Cerrado plant communities. We took advantage of a 2017 wildfire to evaluate the potential for tree cutting and fire to promote the passive restoration of savanna herbaceous plant communities after destruction by exotic tree plantations. We sampled a burned pine plantation (Burned Plantation); a former plantation that was harvested and burned (Harvested & Burned); an unburned former plantation that was harvested, planted with native trees, and treated with herbicide to control invasive grasses (Native Tree Planting); and two old-growth savannas which served as reference communities. Our results confirm that herbaceous plant communities on post-afforestation sites are very different from old-growth savannas. Among post-afforestation sites, Harvested & Burned herbaceous communities were modestly more similar in composition to old-growth savannas, had slightly higher richness of savanna plants (3.8 species per 50-m(2)), and supported the greatest cover of native herbaceous plants (56%). These positive trends in herbaceous community recovery would be missed in assessments of tree cover: whereas canopy cover in the Harvested & Burned site was 6% (less than typical of savannas of the Cerrado), the Burned Plantation and Native Tree Planting supported 34% and 19% cover, respectively. By focusing on savanna herbaceous plants, these results highlight that tree cutting and fire, not simply tree planting and fire exclusion, should receive greater attention in efforts to restore savannas of the Cerrado. Univ Sao Paulo, Escola Super Agr Luiz de Queiroz, Dept Ciencias Biol, Ave Padua Dias 11, BR-13418260 Piracicaba, SP, Brazil Univ Fed Sao Carlos, Dept Biotecnol & Prod Vegetal & Anim, Araras, Brazil Univ Estadual Paulista, Fac Ciencias Agron, Dept Ciencia Florestal, Botucatu, SP, Brazil Inst Florestal Estado Sao Paulo, Floresta Estadual Assis, Assis, Brazil Texas A&M Univ, Dept Ecol & Conservat Biol, College Stn, TX USA Univ Estadual Paulista, Fac Ciencias Agron, Dept Ciencia Florestal, Botucatu, SP, Brazil CAPES: 001 CNPq: 303179/2016-3 U.S. Department of Agriculture, National Institute of Food and Agriculture: 1016880 U.S. Department of Agriculture, National Institute of Food and Agriculture: 12726253 U.S. National Science Foundation: DEB-1931232 more...
- Published
- 2020
- Full Text
- View/download PDF
34. Involvement of Proton Transfer for Carbon Dioxide Reduction Coupled with Extracellular Electron Uptake in Shewanella oneidensis MR‐1
- Author
-
Eugenio La Cava, Junki Saito, Akihiro Okamoto, and Alexis Guionet
- Subjects
Proton ,biology ,Chemistry ,ATPase ,Electron ,biology.organism_classification ,Electrosynthesis ,Analytical Chemistry ,chemistry.chemical_compound ,Biosynthesis ,Electrochemistry ,Extracellular ,Biophysics ,biology.protein ,Shewanella oneidensis ,Electrochemical reduction of carbon dioxide - Published
- 2020
- Full Text
- View/download PDF
35. Development of xanthan gum‐based solid polymer electrolytes with addition of expanded graphite nanosheets
- Author
-
Rogerio Daltro Knuth, Flávio A. Knuth, Guilherme K. Maron, Raphael D. C. Balboni, Mario L. Moreira, Cristiane W. Raubach, Pedro L. G. Jardim, Neftali L. V. Carreno, César O. Avellaneda, Eduardo C. Moreira, and Sérgio S. Cava more...
- Subjects
Polymers and Plastics ,Materials Chemistry ,General Chemistry ,Surfaces, Coatings and Films - Published
- 2022
- Full Text
- View/download PDF
36. Development of xanthan gum‐based solid polymer electrolytes with addition of expanded graphite nanosheets
- Author
-
Knuth, Rogerio Daltro, primary, Knuth, Flávio A., additional, Maron, Guilherme K., additional, Balboni, Raphael D. C., additional, Moreira, Mario L., additional, Raubach, Cristiane W., additional, Jardim, Pedro L. G., additional, Carreno, Neftali L. V., additional, Avellaneda, César O., additional, Moreira, Eduardo C., additional, and Cava, Sérgio S., additional more...
- Published
- 2022
- Full Text
- View/download PDF
37. Partial range of motion and muscle hypertrophy: Not all ROMs lead to Rome—Response
- Author
-
Hernández‐Belmonte, Alejandro, primary, Martínez‐Cava, Alejandro, additional, Vetrovsky, Tomas, additional, Steffl, Michal, additional, Courel‐Ibáñez, Javier, additional, and Pallarés, Jesús G., additional more...
- Published
- 2022
- Full Text
- View/download PDF
38. Enhancement of the Magnetoresistance in the Mobility‐Engineered Compensated Metal Pt 5 P 2
- Author
-
Alex H. Mayo, Hidefumi Takahashi, Shintaro Ishiwata, Karolina Górnicka, Michał J. Winiarski, Jan Jaroszynski, Robert J. Cava, Weiwei Xie, and Tomasz Klimczuk
- Subjects
Electronic, Optical and Magnetic Materials - Published
- 2022
- Full Text
- View/download PDF
39. Ferromagnetic Double Perovskite Semiconductors with Tunable Properties
- Author
-
Jin, Lun, primary, Ni, Danrui, additional, Gui, Xin, additional, Straus, Daniel B., additional, Zhang, Qiang, additional, and Cava, Robert J., additional
- Published
- 2022
- Full Text
- View/download PDF
40. Honeycomb‐Structure RuI 3 , A New Quantum Material Related to α‐RuCl 3
- Author
-
Ni, Danrui, primary, Gui, Xin, additional, Powderly, Kelly M., additional, and Cava, Robert J., additional
- Published
- 2022
- Full Text
- View/download PDF
41. A new strategy proposal to monitor ray fins landings in south‐east Brazil
- Author
-
Marcelo Vianna, Antonio M. Solé-Cava, Rebeca Almeida Marques, and Tainá Guimarães Julio
- Subjects
0106 biological sciences ,Biomass (ecology) ,Ecology ,Cytochrome b ,010604 marine biology & hydrobiology ,Fishing ,Fish fin ,Aquatic Science ,Biology ,010603 evolutionary biology ,01 natural sciences ,Fishery ,Genus ,South east ,Common name ,Identification (biology) ,Nature and Landscape Conservation - Abstract
Statistical fisheries data are usually obtained during landings, through rapid fish classification and their categorization under the trade names given to species or groups of species. However, species classification is often difficult, particularly concerning elasmobranchs whose fins and heads have been removed, leading to labelling errors. The aim of this paper is to identify the ray species composition landed in south‐east Brazil, providing identification strategies to support a plan for more efficient labelling and management. Samples were obtained from artisanal fleet landings, between November 2012 and May 2014. For taxonomic identification of whole or processed animals (n = 279, belonging to 10 species), morphological, metric, and molecular techniques were employed. The common name used by fishermen was more related to the location where they lived than the fishing gear used. Morphometric analyses resulted in pectoral fin to length and weight conversion equations of whole individuals for each species, and 10 variables were found to be diagnostic of each genus. A genetic identification, based on sequencing of the mitochondrial genes cytochrome b and cytochrome oxidase I, was applied to verify morphological identification. A dichotomous key that allowed ray identification at the species level from pectoral fin morphology was developed. The approach was field tested and deemed adequate, leading to a robust monitoring strategy for estimating the biomass of specific landed rays. more...
- Published
- 2019
- Full Text
- View/download PDF
42. Pectin Hydrolysates from Different Cultivars of Pink/Red and White Grapefruits ( Citrus Paradisi [macf.]) as Culture and Encapsulating Media for Lactobacillus Plantarum
- Author
-
Sonia C. Sgroppo, Esteban Gerbino, Andrea Gómez-Zavaglia, and Enzo Luciano Marcelo la Cava
- Subjects
Arabinose ,food.ingredient ,Otras Ingenierías y Tecnologías ,Pectin ,IONIC GELATION ,030309 nutrition & dietetics ,PREBIOTICS ,INGENIERÍAS Y TECNOLOGÍAS ,Xylose ,Alimentos y Bebidas ,03 medical and health sciences ,chemistry.chemical_compound ,0404 agricultural biotechnology ,food ,Citrus paradisi ,DEHYDRATION ,Lactic Acid ,Citrus Pectin ,Food science ,0303 health sciences ,biology ,Hydrolysis ,LACTOBACILLI ,food and beverages ,04 agricultural and veterinary sciences ,biology.organism_classification ,040401 food science ,Culture Media ,Lactic acid ,Freeze Drying ,chemistry ,PECTIN OLIGOSACCHARIDES ,Fermentation ,Pectins ,Sugars ,Lactobacillus plantarum ,Food Science - Abstract
Citrus pectin hydrolysates (Citrus paradisi [Mafc.]) from “Foster,” “Red Shambar,” “Tangelo Orlando,” and “Citrumelo Swingle” cultivars were obtained by partial chemical hydrolysis and their properties as culture media (sole carbon/nutrient source) and encapsulating agents of Lactobacillus plantarum CIDCA 83114 were evaluated. The concentration of neutral sugars was maximal after 2‐hour hydrolysis. All hydrolysates were rich in glucose >xylose >galactose >galacturonic acid >mannose >arabinose. “Citrumelo Swingle” cultivar was the one with the highest concentration of xylose. After 24 hr of fermentation with L. plantarum CIDCA 83114, bacterial viability increased from 6.76 ± 0.14 to almost 9 log CFU/mL, and lactic acid concentration, from 2.63 ± 0.41 to 7.82 ± 0.15 mmol/L in all hydrolysates. Afterwards, bacteria were entrapped in pectate‐calcium beads by ionotropic gelation. Bacterial viability did not significantly decrease after freeze‐drying and storage the beads at 4 °C for 45 days. Fil: la Cava, Enzo Luciano Marcelo. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura. Laboratorio de Tecnología Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gerbino, Oscar Esteban. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Fil: Sgroppo, Sonia Cecilia. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura. Laboratorio de Tecnología Química; Argentina Fil: Gomez Zavaglia, Andrea. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina more...
- Published
- 2019
- Full Text
- View/download PDF
43. Suppression of Murine Lupus by <scp>CD</scp> 4+ and <scp>CD</scp> 8+ Treg Cells Induced by T Cell–Targeted Nanoparticles Loaded With Interleukin‐2 and Transforming Growth Factor β
- Author
-
Sean Bickerton, David A. Horwitz, Antonio La Cava, Michael Koss, and Tarek M. Fahmy
- Subjects
0301 basic medicine ,Interleukin 2 ,Lupus erythematosus ,Systemic lupus erythematosus ,Chemistry ,T cell ,Immunology ,FOXP3 ,medicine.disease ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,Immune system ,Rheumatology ,030220 oncology & carcinogenesis ,medicine ,Cancer research ,Immunology and Allergy ,Ex vivo ,medicine.drug ,Transforming growth factor - Abstract
Objective To develop a nanoparticle (NP) platform that can expand both CD4+ and CD8+ Treg cells in vivo for the suppression of autoimmune responses in systemic lupus erythematosus (SLE). Methods Poly(lactic-co-glycolic acid) (PLGA) NPs encapsulating interleukin-2 (IL-2) and transforming growth factor β (TGFβ) were coated with anti-CD2/CD4 antibodies and administered to mice with lupus-like disease induced by the transfer of DBA/2 T cells into (C57BL/6 × DBA/2)F1 (BDF1) mice. The peripheral frequency of Treg cells was monitored ex vivo by flow cytometry. Disease progression was assessed by measuring serum anti-double-stranded DNA antibody levels by enzyme-linked immunosorbent assay. Kidney disease was defined as the presence of proteinuria or renal histopathologic features. Results Anti-CD2/CD4 antibody-coated, but not noncoated, NPs encapsulating IL-2 and TGFβ induced CD4+ and CD8+ FoxP3+ Treg cells in vitro. The optimal dosing regimen of NPs for expansion of CD4+ and CD8+ Treg cells was determined in in vivo studies in mice without lupus and then tested in BDF1 mice with lupus. The administration of anti-CD2/CD4 antibody-coated NPs encapsulating IL-2 and TGFβ resulted in the expansion of CD4+ and CD8+ Treg cells, a marked suppression of anti-DNA antibody production, and reduced renal disease. Conclusion This study shows for the first time that T cell-targeted PLGA NPs encapsulating IL-2 and TGFβ can expand both CD4+ and CD8+ Treg cells in vivo and suppress murine lupus. This approach, which enables the expansion of Treg cells in vivo and inhibits pathogenic immune responses in SLE, could represent a potential new therapeutic modality in autoimmune conditions characterized by impaired Treg cell function associated with IL-2 deficiency. more...
- Published
- 2019
- Full Text
- View/download PDF
44. Immune off‐target effects of Brentuximab Vedotin in relapsed/refractory Hodgkin Lymphoma
- Author
-
Alessandra Romano, Piera La Cava, Francesco Di Raimondo, Giuseppina Camiolo, Fabrizio Puglisi, Annalisa Chiarenza, Giuseppe A. Palumbo, Giovanna Motta, Nunziatina Laura Parrinello, Cesarina Giallongo, and Daniele Tibullo more...
- Subjects
Adult ,Male ,Oncology ,medicine.medical_specialty ,Myeloid ,Adolescent ,CD30 ,T-Lymphocytes, Regulatory ,Disease-Free Survival ,03 medical and health sciences ,0302 clinical medicine ,Immune system ,Refractory ,hemic and lymphatic diseases ,Internal medicine ,arginase ,Brentuximab Vedotin ,myeloid-derived suppressor cells ,refractory Hodgkin lymphoma ,T-reg ,Biomarkers, Tumor ,medicine ,Refractory Hodgkin Lymphoma ,Humans ,Brentuximab vedotin ,business.industry ,Hematology ,Middle Aged ,Hodgkin Disease ,Neoplasm Proteins ,Survival Rate ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Myeloid-derived Suppressor Cell ,Hodgkin lymphoma ,Female ,business ,030215 immunology ,medicine.drug - Abstract
Hodgkin Lymphoma (HL) is associated with deep microenvironment re-shaping and myeloid dysfunction. Given that only limited data are available regarding the role of Brentuximab Vedotin (BV) as single agent in transplant-naive relapsed/refractory (R/R) patients and its off-target effects on immune system, we evaluated the amount of regulatory T-cells (T-regs), myeloid-derived suppressor cells (MDSC) subpopulations, and their functional marker, serum arginase-1 (s-Arg-1), in peripheral blood of 15 consecutive R/R HL patients. After a median of four BV cycles, the overall response rate (complete response + partial response) was 47%, with 4 (27%) complete metabolic remissions. BV reduced the absolute number of three MDSC subtypes and s-Arg-1 levels. Patients with baseline s-Arg-1 ≥200 ng/ml had inferior progression-free survival at 36 months compared to those with low s-Arg-1. T-regs dysfunction was recovered by BV: absolute T-regs count was increased after treatment with BV, independently of metabolic response achieved, with a significant reduction of CD30+ T-regs. Our data disclose off-target effects of BV in the microenvironment that could explain its deep and durable clinical efficacy. more...
- Published
- 2019
- Full Text
- View/download PDF
45. The Distributional Effects of Monetary Policy: Evidence from Local Housing Markets in Australia
- Author
-
La Cava, Gianni, primary and He, Calvin, additional
- Published
- 2021
- Full Text
- View/download PDF
46. Effects of range of motion on resistance training adaptations: A systematic review and meta‐analysis
- Author
-
Pallarés, Jesús G., primary, Hernández‐Belmonte, Alejandro, additional, Martínez‐Cava, Alejandro, additional, Vetrovsky, Tomas, additional, Steffl, Michal, additional, and Courel‐Ibáñez, Javier, additional more...
- Published
- 2021
- Full Text
- View/download PDF
47. LD‐transpeptidases: the great unknown among the peptidoglycan cross‐linkers
- Author
-
Aliashkevich, Alena, primary and Cava, Felipe, additional
- Published
- 2021
- Full Text
- View/download PDF
48. d‐canavanine affects peptidoglycan structure, morphogenesis and fitness in Rhizobiales
- Author
-
Aliashkevich, Alena, primary, Howell, Matthew, additional, Brown, Pamela J. B., additional, and Cava, Felipe, additional
- Published
- 2021
- Full Text
- View/download PDF
49. Characterization of hippocampal amyloidosis induced by amyloid‐ β in behaving mice
- Author
-
Irene Sánchez-Rodríguez, Agnès Gruart, José M. Delgado-García, Sara Temprano-Carazo, Jennifer Mayordomo-Cava, Guillermo Iborra-Lázaro, Lydia Jiménez-Díaz, Souhail Djebari, and Juan D. Navarro-López
- Subjects
Pathology ,medicine.medical_specialty ,Amyloid β ,Epidemiology ,Chemistry ,Health Policy ,Amyloidosis ,Hippocampal formation ,medicine.disease ,Psychiatry and Mental health ,Cellular and Molecular Neuroscience ,Developmental Neuroscience ,medicine ,Neurology (clinical) ,Geriatrics and Gerontology - Published
- 2020
- Full Text
- View/download PDF
50. The h ‐Sb x WO 3+2 x Oxygen Excess Antimony Tungsten Bronze
- Author
-
Fabian O. von Rohr, Jessica J. Frick, Robert J. Cava, Huiwen Ji, Jing Tao, Greta R. Patzke, Karoline Stolze, and Alice Ryser
- Subjects
010405 organic chemistry ,Organic Chemistry ,Fermi level ,chemistry.chemical_element ,General Chemistry ,Atmospheric temperature range ,engineering.material ,Tungsten ,010402 general chemistry ,01 natural sciences ,Catalysis ,0104 chemical sciences ,symbols.namesake ,Crystallography ,Octahedron ,Antimony ,chemistry ,Electrical resistivity and conductivity ,engineering ,symbols ,Crystallite ,Bronze - Abstract
We describe the previously unreported oxygen excess hexagonal antimony tungsten bronze with composition Sb0.5W3O10, in the following denoted as h‐SbxWO3+2x with x=0.167, to demonstrate its analogy to classical AxWO3 tungsten bronzes. This compound forms in a relatively narrow temperature range between 580 °C more...
- Published
- 2019
- Full Text
- View/download PDF
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.