1. Antimicrobial prophylaxis in adults and children undergoing hematopoietic cell transplantation: 2021 Polish recommendations
- Author
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Iwona Hus, Bogusław Machaliński, Mariola Sedzimirska, Jan Maciej Zaucha, Krzysztof Czyżewski, Grzegorz Helbig, Katarzyna Drabko, Adam Fronczak, Olga Zając-Spychała, Ewa Lech-Marańda, Agnieszka Wierzbowska, Krzysztof Kałwak, Agnieszka Druzd-Sitek, Bartłomiej Baumert, Malgorzata Sobczyk-Kruszelnicka, Ewa Lutwin, Dorota Hawrylecka, Katarzyna Smalisz, Tomasz Wróbel, Beata Piątkowska-Jakubas, Kazimierz Hałaburda, Piotr Rzepecki, Marek Hus, Sebastian Giebel, Agnieszka Sobkowiak-Sobierajska, Grzegorz W. Basak, Edyta Cichocka, Aleksandra Krasowska-Kwiecień, Jacek Wachowiak, Anna Czyż, Jan Styczyński, Adam Walter-Croneck, Piotr Boguradzki, Jarosław Dybko, Anna Łojko, Marek Ussowicz, Lidia Gil, Maria Bieniaszewska, Tomasz Szczepański, Jolanta Goździk, Agnieszka Piekarska, and Agnieszka Zaucha-Prażmo
- Subjects
medicine.medical_specialty ,Hematopoietic cell ,business.industry ,Incidence (epidemiology) ,Hematology ,Guideline ,Antimicrobial ,medicine.disease ,Toxoplasmosis ,Vaccination ,Transplantation ,Leukemia ,Oncology ,Medicine ,business ,Intensive care medicine - Abstract
Infections are still a major reason of morbidity and one of the most common causes of death after hematopoietic cell transplantation (HCT). Antimicrobial prophylaxis plays a crucial role in decreasing non-relapse mortality after HCT. The objective of this guideline paper is presentation of current recommendations of antimicrobial prophylaxis for children and adults after hematopoietic cell transplantation, prepared in cooperation of Polish scientific hematological societies. Recommendations were prepared by the working group and finally approved by all 23 Polish transplant centers for children and adults. Existing ECIL (European Conference on Infections in Leukemia) and EBMT (European Society of Blood and Marrow Transplantation) guidelines, as well as results of survey performed among all Polish transplant centers, were the background material for working group. Recommendations are presented in sections dedicated to antibacterial prophylaxis, antifungal prophylaxis, antiviral prophylaxis, as well as prophylaxis of toxoplasmosis and infections with Pneumocystis jiroveci. Recommendations on principles of vaccination against COVID-19 are provided based on the state of knowledge in September 2021. A section on guidelines of environmental prophylaxis is also presented.
- Published
- 2021
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