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Introduccion. La demencia es un proceso neurodegenerativo de dificil diagnostico en su fase precoz. Se ha definido bien clinicamente, aunque su diagnostico neurofisiologico, de neuroimagen y metabolico es todavia insuficiente. Pacientes y metodos. Se realizo registro magnetoencefalografico (equipo whole-head de 148 canales Magnes 2500 WH) y valoracion mediante examen minimental en 31 sujetos. Se realizo analisis estadistico para correlacionar el numero de dipolos de ondas lentas con las variables neuropsicologicas. Resultados. En el 63,3% (21 pacientes) se objetivaron durante el analisis MEG dipolos de ondas lentas en lobulos temporales, y en un 52,3% de estos la localizacion era bitemporal. La media de los dipolos en lobulo temporal derecho fue de 119,5 ± 23,3, y en lobulo temporal izquierdo de 126,2 ± 19,8. Un 25% (ocho pacientes) presentaron dipolos de ondas lentas en lobulos parietales y en cinco de ellos la localizacion fue biparietal. La correlacion entre las puntuaciones medias del examen minimental y los dipolos en lobulo temporal fue r= -0,84. Conclusion. Los hallazgos de la MEG indican que el numero de dipolos de ondas lentas en lobulos temporales se relaciona con puntuaciones bajas en el examen minimental. La MEG puede ser un metodo complementario util en la evaluacion y seguimiento del grado de deterioro cognitivo en estos pacientes

Introduction Whole head magnetoencephalography (MEG) systems facilitate simultaneous recording from the entire brain surface and deep structures. Thus MEG may be accepted as a clinically feasible method for the evaluation of epileptic patients not diagnosed with EEG. Clinical case A 11 year old female, with tonic generalized seizures since birth. At the present time, seizures consist of initial focal signs followed by fear sensation and both eyes and cephalic deviation to the right, tonic extension of the superior limbs and prolonged apnea. Complementary examinations (EEG, Holter EEG, Video EEG, CT, MRI, SPECT) were normal. MEG study was conclusive, diagnosing sharp waves in the internal face of the left precentral circunvolution. Conclusions MEG study s utility in seizures focus localization and pseudo seizures differential diagnosis has been demonstrated.

INTRODUCTION Lesions of the pyramidal system are characterized by their effects on qualitative aspects of movement. One of the features of pyramidal defects is the presence of associated movements or synkinesis. CLINICAL CASE We present a case with residual associated electromyographic (EMG) response in a patient who had had a capsular stroke 11 months previously. The patient presented with acute onset of a syndrome of purely motor right hemiparesis (PMH) which improved satisfactorily with complete functional recovery three months later. Eleven months after the acute episode, there was good functional recovery and neurophysiological examination showed the presence of EMG responses associated with the unaffected limb (left hand) when voluntary movements were made with the right hand. CONCLUSION The appearance of qualitative alterations of movement associated with pyramidal syndromes and particularly the presence of associated EMG responses in the case of capsular infarct described, may reflect the different processes of reinnervation and functional reorganization which occur following the lesion and which are involved in recovery of motor function.