1. Remission of type 2 diabetes mellitus after bariatric surgery-comparison between procedures
- Author
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Fernández-Soto, María L., Martín-Leyva, Ana, González-Jiménez, Amalia, García-Rubio, Jesús, Cózar-Ibáñez, Antonio, Zamora-Camacho, Francisco J., Leyva-Martínez, María S., Jiménez-Ríos, Jose A., Escobar-Jiménez, Fernando, and Fundación Ramón Areces
- Subjects
Adult ,Male ,Bariatric surgery ,Gastric bypass ,Middle Aged ,Obesity, Morbid ,Treatment Outcome ,Diabetes Mellitus, Type 2 ,Type 2 diabetes mellitus ,Disease Progression ,Humans ,Female ,Prospective Studies ,Sleeve gastrectomy ,Biliopancreatic diversion - Abstract
[Introduction]: We aimed to assess the mid-Term type 2 diabetes mellitus recovery patterns in morbidly obese patients by comparing some relevant physiological parameters of patients of bariatric surgery between two types of surgical procedures: mixed (roux-en-Y gastric bypass and biliopancreatic diversion) and restrictive (sleeve gastrectomy)., [Material and methods]: This is a prospective and observational study of co-morbid, type 2 diabetes mellitus evolution in 49 morbidly obese patients: 37 underwent mixed surgery procedures and 12 a restrictive surgery procedure. We recorded weight, height, body mass index, and glycaemic, lipid, and nutritional blood parameters, prior to procedure, as well as six and twelve months post-operatively. In addition, we tested for differences in patient recovery and investigated predictive factors in diabetes remission., [Results]: Both glycaemic and lipid profiles diminished significantly to healthy levels by 6 and 12 months post intervention. Type 2 diabetes mellitus showed remission in more than 80% of patients of both types of surgical procedures, with no difference between them. Baseline body mass index, glycated haemoglobin, and insulin intake, among others, were shown to be valuable predictors of diabetes remission one year after the intervention., [Conclusions]: The choice of the type of surgical procedure did not significantly affect the remission rate of type 2 diabetes mellitus in morbidly obese patients., The Authors would like to thank the personnel of the Clinic Hospital “San Cecilio” (Granada, Spain) for their constant support and the patients for participating in this study. We also thank Ruth Martín for improving the English. Francisco Javier Zamora Camacho was partly supported by a Ramón Areces Foundation postdoctoral fellowship and Juan de la Cierva-Formación postdoctoral fellowship by the Spanish government.
- Published
- 2017