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Objective: identifying changes occurred during the evaluation of health-related quality of life (HRQOL) of adults between the third and the sixth month after surgery. Methods: quantitative approach, longitudinal design, conducted from June to November 2013. A characterization questionnaire and the Short Form Health Survey (SF-36) were applied. Descriptive analyses, Mann-Whitney and Wilcoxon test were carried out. Significance level p=0.05. Results: 24 adults participated. There was a reduction of average scores in five of the eight domains of the SF-36, representing worsening of HRQOL in the sixth month. The domain Physical aspect was the most affected. The averages of Pain domain were higher and statistically significant for women (p=0.04), there was improvement in the general health status (p=0.01) and Emotional aspect (p=0,05) in the sixth month. Conclusion: there is worsening of HRQOL between adults undergoing surgery of hip or femur during the first six months after discharge the day of surgery.