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There is a range of processed foods that satisfy hunger, but do not nourish, causing a progressive decline in human health; however, bread enriched with micronutrients has a beneficial effect on health, contributing to the functioning of the organism. The objective of this research was to develop a functional bakery product based on wheat and butternut squash flours from two cultivars; An experimental work with six T0 treatments was proposed: 100% wheat flour (WF) – 0% butternut squash flour (BSF); T1: 80% WF – 20% BSF; T2: 85% WF – 15% BSF; T3: 90% WF – 10% BSF; T4: 95% WF – 5% BSF; T5: 97% WF – 3% BSF and three repetitions per treatment, under a completely randomized design, the chemical, physical and organoleptic properties were evaluated in each treatment by cultivating; for sensory testing, the sensory test was performed. The results indicated that all the treatments have a protein content between 9.59 - 9.78% and total carotenoids between 18.60 - 26.44 µg./g. on a dry basis; the sensory test Friedman established that the best treatment using flour from the Abanico 75 cultivar was T3 for flavor and color characteristics, and T4 for palatability, and when using flour from the Dorado cultivar for the same characteristics, the best treatment was T3 with 10% of butternut squash flour. [ABSTRACT FROM AUTHOR]