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66 results on '"Drosten, Christian"'

1. Biphasic MERS-CoV Incidence in Nomadic Dromedaries with Putative Transmission to Humans, Kenya, 2022-2023

Author

Ogoti, Brian Maina, Riitho, Victor, Wildemann, Johanna, Mutono, Nyamai, Tesch, Julia, Rodon, Jordi, Harichandran, Kaneemozhe, Emanuel, Jackson, Moncke-Buchner, Elisabeth, Kiambi, Stella, Oyugi, Julius, Mureithi, Marianne, Corman, Victor M., Drosten, Christian, Thumbi, Samuel M., and Muller, Marcel A.

Subjects
Zoonoses -- Risk factors -- Diagnosis, Disease transmission -- Risk factors, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in dromedary camels from the Arabian Peninsula and Africa; seroprevalence is >75% (1-3). Zoonotic transmission to humans has occurred sporadically, mainly on [...]

Published
2024
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2. Divergent Genotype of Hepatitis A Virus in Alpacas, Bolivia, 2019

Author

Veith, Talitha, Beltran-Saavedra, L. Fabian, Bleicker, Tobias, Schmidt, Marie Luisa, Mollericona, Jose L., Grutzmacher, Kim, Wallace, Rob, Drexler, Jan Felix, Walzer, Christian, Jones, Terry C., Drosten, Christian, and Corman, Victor Max

Subjects
Hepatitis A -- Risk factors -- Causes of, Alpaca -- Health aspects, Genotype -- Research, Hepatitis A virus -- Identification and classification -- Genetic aspects -- Distribution, Virus research, Company distribution practices, Health
Abstract

Hepatitis A virus (HAV) causes acute hepatitis in humans worldwide; [approximately equal to] 159 million infections and [approximately equal to] 39,000 deaths were associated with HAV in 2019 (1), despite [...]

Published
2023
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3. US National Institutes of Health Prioritization of SARS-CoV-2 Variants

Author

Turner, Sam, Alisoltani, Arghavan, Bratt, Debbie, Cohen-Lavi, Liel, Dearlove, Bethany L., Drosten, Christian, Fischer, Will M., Fouchier, Ron A.M., Gonzalez-Reiche, Ana Silvia, Jaroszewski, Lukasz, Khalil, Zain, LeGresley, Eric, Johnson, Marc, Jones, Terry C., Muhlemann, Barbara, O'Connor, David, Sedova, Mayya, Shukla, Maulik, Theiler, James, Wallace, Zachary S., Yoon, Hyejin, Zhang, Yun, van Bakel, Harm, Degrace, Marciela M., Ghedin, Elodie, Godzik, Adam, Hertz, Tomer, Korber, Bette, Lemieux, Jacob, Niewiadomska, Anna M., Post, Diane J., Rolland, Morgane, Scheuermann, Richard, and Smith, Derek J.

Subjects
Values -- Analysis, Microbial mutation -- Health aspects, Epidemiology -- Methods, Health
Abstract

As part of the US National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) SARS-CoV-2 Assessment of Viral Evolution (SAVE) effort to combat the SARS-CoV-2 pandemic, [...]

Published
2023
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4. Effectiveness of Naturally Acquired and Vaccine-Induced Immune Responses to SARS-CoV-2 Mu Variant

Author

de Oliveira-Filho, Edmilson F., Rincon-Orozco, Bladimiro, Jones-Cifuentes, Natalia, Pena-Lopez, Brigitte, Muhlemann, Barbara, Drosten, Christian, Moreira-Soto, Andres, and Drexler, Jan Felix

Subjects
Immune response -- Evaluation, Company distribution practices, Health
Abstract

Diverse SARS-CoV-2 variants have arisen during the pandemic. As of May 4, 2022, there had been 2 recognized variants of concern (VOC), Delta and Omicron, in addition to earlier emerging [...]

Published
2022
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5. Emergence of SARS-CoV-2 Delta Variant, Benin, May--July 2021

Author

Yadouleton, Anges, Sander, Anna-Lena, Adewumi, Praise, de Oliveira Filho, Edmilson F., Tchibozo, Carine, Hounkanrin, Gildas, Rene, Keke K., Ange, Dossou, Kohoun, Rodrigue K., Nari, Ramalia Chabi, Salifou, Sourakatou, Saizonou, Raoul, Kakai, Clement G., Bedie, Sonia V., Onifade, Fattah Al, Nagel, Michael, Aissi, Melchior A. Joel, Akogbeto, Petas, Drosten, Christian, Wulf, Ben, Moreira-Soto, Andres, Djingarey, Mamoudou Harouna, Hounkpatin, Benjamin, and Drexler, Jan Felix

Subjects
Epidemics -- Statistics -- Causes of -- Benin, Health
Abstract

Numerous genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged globally since the start of the coronavirus disease (COVID-19) pandemic (https://cov-lineages.org). By September 2021, the World Health [...]

Published
2022
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6. Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021

Author

Sander, Anna-Lena, Yadouleton, Anges, de Oliveira Filho, Edmilson F., Tchibozo, Carine, Hounkanrin, Gildas, Badou, Yvette, Adewumi, Praise, Rene, Keke K., Ange, Dossou, Sourakatou, Salifou, Sedjro, Eclou, Aissi, Melchior A. Joel, Fidelia, Hinson, Djingarey, Mamoudou Harouna, Nagel, Michael, Jo, Wendy Karen, Moreira-Soto, Andres, Drosten, Christian, Landt, Olfert, Corman, Victor Max, Hounkpatin, Benjamin, and Drexler, Jan Felix

Subjects
Gene mutations -- Research, Epidemics -- Causes of -- Benin, Virus research, Health
Abstract

Genomic surveillance is key to elucidate coronavirus disease (COVID-19) transmission chains and to monitor emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants associated with partial or complete immune escape [...]

Published
2021
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7. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Author

Schwarz, Tatjana, Tober-Lau, Pinkus, Hillus, David, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Koch, Willi, Landgraf, Irmgard, Michel, Janine, Bergfeld, Leon, Niemeyer, Daniela, Muhlemann, Barbara, Conrad, Claudia, Dang-Heine, Chantip, Kasper, Stefanie, Munn, Friederike, Kappert, Kai, Nitsche, Andreas, Tauber, Rudolf, Schmidt, Sein, Kopankiewicz, Piotr, Bias, Harald, Seybold, Joachim, von Kalle, Christof, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Corman, Victor M., and Kurth, Florian

Subjects
Antigen-antibody reactions -- Health aspects, Aged patients -- Care and treatment, T cells -- Health aspects, Immune response -- Health aspects, Health
Abstract

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in [...]

Published
2021
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8. Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021

Author

Tober-Lau, Pinkus, Schwarz, Tatjana, Hillus, David, Spieckermann, Jana, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Koch, Willi, Bergfeld, Leon, Niemeyer, Daniela, Muhlemann, Barbara, Conrad, Claudia, Kasper, Stefanie, Munn, Friederike, Kunitz, Frank, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Kurth, Florian, and Corman, Victor M.

Subjects
Vaccination -- Patient outcomes, Epidemics -- Risk factors -- Demographic aspects -- Control -- Germany, Long-term care facilities -- Management -- Safety and security measures, Company business management, Health
Abstract

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 [...]

Published
2021
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9. Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak Related to a Nightclub, Germany, 2020

Author

Muller, Nadine, Kunze, Mareike, Steitz, Fabienne, Saad, Neil J., Muhlemann, Barbara, Beheim-Schwarzbach, Jorn I., Schneider, Julia, Drosten, Christian, Murajda, Lukas, Kochs, Sandra, Ruscher, Claudia, Walter, Jan, Zeitlmann, Nadine, and Corman, Victor M.

Subjects
Epidemics -- Control -- Germany, Safety regulations -- Evaluation, Sentinel health events -- Methods, Nightclubs -- Health aspects, Health
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading events are particularly linked to indoor settings, such as religious venues (1), restaurants (2), and bars or nightclubs (3-6). To provide further [...]

Published
2021
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10. Hepatitis E Virus Genotype 7 RNA and Antibody Kinetics in Naturally Infected Dromedary Calves, United Arab Emirates

Author

Corman, Victor M., Nagy, Peter, Ostermann, Stefanie, Arloth, Jacqueline, Liljander, Anne, Barua, Rajib, Gupta, Aungshuman Das, Hakimuddin, Fatima, Juhasz, Judit, Wernery, Ulrich, and Drosten, Christian

Subjects
Hepatitis E -- Genetic aspects, Cattle -- Genetic aspects, Infection -- Genetic aspects, Antibodies -- Genetic aspects, Food contamination, RNA -- Genetic aspects, Swine -- Genetic aspects, Health
Abstract

Infection with hepatitis E viruses (HEVs) is one of the major causes of acute hepatitis in humans (1). Most HEV strains infecting humans belong to the virus species Orthohepevirus A [...]

Published
2020
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11. Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols

Author

Kratzel, Annika, Todt, Daniel, Vkovski, Philip, Steiner, Silvio, Gultom, Mitra, Thao, Tran Thi Nhu, Ebert, Nadine, Holwerda, Melle, Steinmann, Jorg, Niemeyer, Daniela, Dijkman, Ronald, Kampf, Gunter, Drosten, Christian, Steinmann, Eike, Thiel, Volker, and Pfaender, Stephanie

Subjects
Severe acute respiratory syndrome -- Health aspects, Alcohols -- Health aspects, Coronaviruses -- Health aspects, COVID-19 -- Health aspects, Health
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third highly pathogenic human coronavirus to cross the species barrier into the human population during the past 20 years (2-3). SARS-CoV-2 [...]

Published
2020
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12. Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Patients

Author

Okba, Nisreen M.A., Muller, Marcel A., Li, Wentao, Wang, Chunyan, GeurtsvanKessel, Corine H., Corman, Victor M., Lamers, Mart M., Sikkema, Reina S., de Bruin, Erwin, Chandler, Felicity D., Yazdanpanah, Yazdan, Hingrat, Quentin Le, Descamps, Diane, Houhou-Fidouh, Nadhira, Reusken, Chantal B.E.M., Bosch, Berend-Jan, Drosten, Christian, Koopmans, Marion P.G., and Haagmans, Bart L.

Subjects
Severe acute respiratory syndrome -- Health aspects, Enzyme-linked immunosorbent assay -- Health aspects, Coronaviruses -- Health aspects, Medical research -- Health aspects, Immunoglobulin A -- Health aspects, Immunoglobulin G -- Health aspects, COVID-19 -- Health aspects, Health
Abstract

In December 2019, a new coronavirus emerged in China and caused an acute respiratory disease now known as coronavirus disease 2019 (COVID-19) (1). The virus was identified to be a [...]

Published
2020
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13. Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus

Author

Harvey, Ruth, Mattiuzzo, Giada, Hassall, Mark, Sieberg, Andrea, Muller, Marcel A., Drosten, Christian, Rigsby, Peter, and Oxenford, Christopher J.

Subjects
Algorithms -- Comparative analysis -- Health aspects, Middle East respiratory syndrome -- Comparative analysis -- Health aspects, Beef cattle, Algorithm, Health, World Health Organization
Abstract

Since the emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 (1), more than 2,250 laboratory-confirmed cases have been reported to the World Health Organization (WHO); approximately one third [...]

Published
2019
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14. Sand Fly-Associated Phlebovirus with Evidence of Neutralizing Antibodies in Humans, Kenya

Author

Tchouassi, David P., Marklewitz, Marco, Chepkorir, Edith, Zirkel, Florian, Agha, Sheila B., Tigoi, Caroline C., Koskei, Edith, Drosten, Christian, Borgemeister, Christian, Torto, Baldwyn, Junglen, Sandra, and Sang, Rosemary

Subjects
Mosquitoes -- Analysis -- Health aspects, Amino acids -- Analysis -- Health aspects, Infection -- Analysis -- Health aspects, Genomes -- Analysis -- Health aspects, Antibodies -- Analysis -- Health aspects, Genomics -- Analysis -- Health aspects, Swine -- Analysis -- Health aspects, Rural areas, Beef cattle, Wildlife, Newborn infants, Novels, Health
Abstract

Disease outbreaks caused by Zika, dengue, yellow fever, chikungunya, and Rift Valley fever viruses illustrate the threat posed by arthropodborne viruses (arboviruses), which affect millions of patients worldwide each year [...]

Published
2019
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15. Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

Author

Bozza, Fernando A., Moreira-Soto, Andres, Rockstroh, Alexandra, Fischer, Carlo, Nascimento, Alessandra D., Calheiros, Andrea S., Drosten, Christian, Bozza, Patricia T., Souza, Thiago Moreno L., Ulbert, Sebastian, and Drexler, Jan Felix

Subjects
Dengue virus -- Health aspects, Zika virus -- Health aspects, Infection -- Health aspects, Antibodies -- Health aspects, Immune response, Recurrence (Disease), Medical tests, Antigens, Health
Abstract

In 2013, Zika virus and chikungunya virus (CHIKV) emerged in Latin America (1,2). Their overlapping symptoms challenge accurate diagnosis on the basis of clinical manifestations (3). Direct Zika virus and [...]

Published
2019
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16. External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

Author

Fischer, Carlo, Pedroso, Celia, Mendrone, Alfredo, Jr., de Filippis, Ana Maria Bispo, Vallinoto, Antonio Carlos Rosario, Ribeiro, Bergmann Morais, Durigon, Edison Luiz, Marques, Ernesto T.A., Jr., Campos, Gubio S., Viana, Isabelle F.T., Levi, Jose Eduardo, Scarpelli, Luciano Cesar, Nogueira, Mauricio Lacerda, de Souza Bastos, Michele, Souza, Nathalia C. Santiago, Khouri, Ricardo, Lira, Sanny M. Costa, Komninakis, Shirley Vasconcelos, Baronti, Cecile, Charrel, Remi N., Kummerer, Beate M., Drosten, Christian, Brites, Carlos, de Lamballerie, Xavier, Niedrig, Matthias, Netto, Eduardo Martins, and Drexler, Jan Felix

Subjects
Medical tests -- Health aspects -- Usage, Patient care -- Analysis, Zika virus -- Research -- Health aspects -- Causes of, Health, World Health Organization
Abstract

The catastrophic Zika virus outbreak in the Americas has affected millions of persons. Brazil was the most affected country and reported [approximately equal to] 95% of all cases of suspected [...]

Published
2018
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17. Lineage-Specific Real-Time Reverse Transcription PCR for Yellow Fever Virus Outbreak Surveillance, Brazil

Author

Fischer, Carlo, Torres, Maria C., Patel, Pranav, Moreira-Soto, Andres, Gould, Ernest A., Charrel, Remi N., de Lamballerie, Xavier, Nogueira, Rita Maria Ribeiro, Sequeira, Patricia C., Rodrigues, Cintia D.S., Kummerer, Beate M., Drosten, Christian, Landt, Olfert, de Filippis, Ana Maria Bispo, and Drexler, Jan Felix

Subjects
Polymerase chain reaction, Yellow fever -- Development and progression, Transcription (Genetics), Vaccination, Health
Abstract

Yellow fever virus (YFV) is a mosquitoborne member of the genus Flavivirus within the family Flaviviridae (online Technical Appendix Figure 1, panel A, https://wwwnc.cdc.gov/EID/article/23/11/17-1131-Techapp1.pdf) that is endemic to Africa and [...]

Published
2017
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18. Hepatitis E Virus Infection in European Brown Hares, Germany, 2007-2014

Author

Corman, Victor Max, Hilgensloh, Laura, Voigt, Ulrich, Marklewitz, Marco, Siebert, Ursula, Drosten, Christian, and Drexler, Jan Felix

Subjects
Hepatitis E -- Health aspects, Medical research -- Health aspects, Infection -- Health aspects, Zoonoses -- Health aspects, Rabbits -- Health aspects, Genomics -- Health aspects, Pets, Climate, Health
Abstract

Hepatitis E virus (HEV; family Hepeviridae, genus Orthohepevirus) is a major cause of acute hepatitis in humans worldwide. Large outbreaks have included waterborne HEV in the tropics and zoonotic infections [...]

Published
2019
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19. Hepatitis E virus infection in dromedaries, North and East Africa, United Arab Emirates, and Pakistan, 1983-2015

Author

Rasche, Andrea, Saqib, Muhammad, Liljander, Anne M., Bornstein, Set, Zohaib, Ali, Renneker, Stefanie, Steinhagen, Katja, Wernery, Renate, Younan, Mario, Gluecks, Ilona, Hilali, Mosaad, Musa, Bakri E., Jores, Joerg, Wernery, Ulrich, Drexer, Jan Felix, Drosten, Christian, and Corman, Victor Max

Subjects
Hepatitis E -- Health aspects, Infection -- Health aspects, Food contamination -- Health aspects, Health
Abstract

Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide (1). Four HEV genotypes belonging to the species Orthohepevirus A are commonly found in humans (HEV-1 through HEV-4). [...]

Published
2016
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20. Mers-cov antibodies in humans, Africa, 2013-2014

Author

Liljander, Anne, Meyer, Benjamin, Jores, Joerg, Muller, Marcel A., Lattwein, Erik, Njeru, Ian, Bett, Bernard, Drosten, Christian, and Corman, Victor Max

Subjects
Viral antibodies -- Health aspects, Antibodies -- Health aspects, Livestock -- Health aspects, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) infection causes severe respiratory illness in humans. Some cases have been sporadic, but others have been part of nosocomial outbreaks mainly on the Arabian [...]

Published
2016
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21. Microevolution of outbreak-associated Middle East respiratory syndrome coronavirus, South Korea, 2015

Author

Seong, Moon-Woo, Kim, So Yeon, Corman, Victor Max, Kim, Taek Soo, Cho, Sung Im, Kim, Man Jin, Lee, Seung Jun, Lee, Jee-Soo, Seo, Soo Hyun, Ahn, Ji Soo, Yu, Byeong Su, Park, Nare, Oh, Myoung-don, Park, Wan Beom, Lee, Ji Yeon, Kim, Gayeon, Joh, Joon Sung, Jeong, Ina, Kim, Eui Chong, Drosten, Christian, and Park, Sung Sup

Subjects
Evolution -- Analysis, Genomics -- Analysis, Phylogeny -- Analysis, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV), first detected in Saudi Arabia in 2012, is a novel human pathogen that causes severe respiratory illness (1). Phylogenetic analyses and transmission studies suggest [...]

Published
2016
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22. No evidence of Gouleako and Herbert virus infections in pigs, cote d'Ivoire and Ghana

Author

Junglen, Sandra, Marklewitz, Marco, Zirkel, Florian, Wollny, Robert, Meyer, Benjamin, Heidemann, Hanna, Metzger, Sonja, Annan, Augustina, Dei, Dickson, Leendertz, Fabian H., Oppong, Samuel, and Drosten, Christian

Subjects
Antiviral agents -- Analysis, Swine -- Analysis, Biological response modifiers -- Analysis, Infection -- Analysis, Resveratrol -- Analysis, Health
Abstract

Orthobunyaviruses and phleboviruses are transmitted to animals and humans by blood-feeding arthropods such as mosquitoes, sandflies, and ticks (1,2). Infection can cause systemic disease, including encephalitis or hemorrhagic fevers. Members [...]

Published
2015
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23. Occupational exposure to dromedaries and risk for MERS-CoV infection, Qatar, 2013-2014

Author

Reusken, Chantal B.E.M., Farag, Elmoubasher A.B.A., Haagmans, Bart L., Mohran, Khaled A., Godeke, Gert-Jan, Raj, V. Stalin, Alhajri, Farhoud, Marri, Salih A. Al-, Romaihi, Hamad E. Al-, Thani, Mohamed Al-, Bosch, Berend-Jan, van der Eijk, Annemiek A., Sayed, Ahmed M. El-, Ibrahim, Adel K., Molawi, N. Al-, Muller, Marcel A., Pasha, Syed K., Drosten, Christian, AlHajri, Mohd M., and Koopmans, Marion P.G.

Subjects
Resveratrol, Health
Abstract

Since Middle East respiratory syndrome coronavirus (MERS-CoV) was first detected in 2012, approximately 1,000 human infections have been reported to the World Health Organization, all linked to residence in or [...]

Published
2015
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24. Human-bat interactions in rural West Africa

Author

Anti, Priscilla, Owusu, Michael, Agbenyega, Olivia, Annan, Augustina, Badu, Ebenezer Kofi, Nkrumah, Evans Ewald, Tschapka, Marco, Oppong, Samuel, Adu-Sarkodie, Yaw, and Drosten, Christian

Subjects
Bats, Disease transmission, Human-animal relationships, Health
Abstract

Bats are increasingly being recognized as hosts for pathogens that affect humans and livestock (1). The 2014-2015 outbreak of Ebola virus disease in West Africa demonstrates how human-bat interactions in [...]

Published
2015
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25. Novel arenavirus isolates from Namaqua rock mice, Namibia, southern Africa

Author

Witkowski, Peter T., Kallies, Rene, Hoveka, Julia, Auste, Brita, Ithete, Ndapewa L., Soltys, Katarina, Szemes, Tomas, Drosten, Christian, Preiser, Wolfgang, Klempa, Boris, Mfune, John K.E., and Kruger, Detlev H.

Subjects
Health
Abstract

Arenaviruses are known to cause severe hemorrhagic fevers across the globe with case fatality rates up to 30% (1). The viruses possess a bisegmented, single-stranded RNA genome with ambisense coding [...]

Published
2015
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26. Acute Middle East respiratory syndrome coronavirus infection in livestock dromedaries, Dubai, 2014

Author

Wernery, Ulrich, Corman, Victor M., Wong, Emily Y.M., Tsang, Alan K.L., Muth, Doreen, Lau, Susanna K.P., Khazanehdari, Kamal, Zirkel, Florian, Ali, Mansoor, Nagy, Peter, Juhasz, Jutka, Wernery, Renate, Joseph, Sunitha, Syriac, Ginu, Elizabeth, Shyna K., Patteril, Nissy Annie Georgy, Woo, Patrick C.Y., and Drosten, Christian

Subjects
Coronaviruses -- Identification and classification -- Health aspects, Livestock -- Diseases -- Medical examination, Company distribution practices, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) causes outbreaks and isolated cases of severe respiratory disease in humans. The virus is transmissible from human to human, but the focus of infection [...]

Published
2015
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27. Time course of MERS-CoV infection and immunity in dromedary camels

Author

Meyer, Benjamin, Juhasz, Judit, Barua, Rajib, Gupta, Aungshuman Das, Hakimuddin, Fatima, Corman, Victor M., Muller, Marcel A., Wernery, Ulrich, Drosten, Christian, and Nagy, Peter

Subjects
Vaccination -- Dosage and administration, Viral antibodies -- Research, Antibodies -- Research, Health
Abstract

In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged on the Arabian Peninsula (1). As of February 2016 the virus has caused 1,638 human infections, including 587 deaths (2). Zoonotic [...]

Published
2016
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28. Antibodies against MERS Coronavirus in Dromedary Camels, Kenya, 1992-2013

Author

Corman, Victor M., Jores, Joerg, Meyer, Benjamin, Younan, Mario, Liljander, Anne, Said, Mohammed Y., Gluecks, Ilona, Lattwein, Erik, Bosch, Berend-Jan, Drexler, Jan Felix, Bornstein, Set, Drosten, Christian, and Muller, Marcel A.

Subjects
Camels -- Health aspects, Viral antibodies -- Research -- Usage -- Health aspects, Antibodies -- Research -- Usage -- Health aspects, Health
Abstract

Middle East respiratory syndrome coronavirus (MERSCoV) was discovered in a patient from Saudi Arabia in 2012 and has since caused ≥ 250 human infections and 93 deaths (1). The evolutionary [...]

Published
2014
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29. Human infection with MERS Coronavirus after exposure to infected camels, Saudi Arabia, 2013

Author

Memish, Ziad A., Cotten, Matthew, Meyer, Benjamin, Watson, Simon J., Alsahafi, Abdullah J., Rabeeah, Abdullah A. Al, Corman, Victor Max, Sieberg, Andrea, Makhdoom, Hatem Q., Assiri, Abdullah, Masri, Malaki Al, Aldabbagh, Souhaib, Bosch, Berend-Jan, Beer, Martin, Muller, Marcel A., Kellam, Paul, and Drosten, Christian

Subjects
Camels -- Influence, Disease transmission -- Research, Coronaviruses -- Influence, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 in a cell culture taken from a patient who died of pneumonia in Saudi Arabia (1). Since 2012, at least [...]

Published
2014
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30. Contact investigation for imported case of middle East respiratory syndrome, Germany

Author

Reuss, Annicka, Litterst, Annette, Drosten, Christian, Seilmaier, Michael, Bohmer, Merle, Graf, Petra, Gold, Hermann, Wendtner, Clemens-Martin, Zanuzdana, Arina, Schaade, Lars, Haas, Walter, and Buchholz, Udo

Subjects
Infection control, Cross infection, Nosocomial infections, Company legal issue, Health, World Health Organization -- Investigations
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) infection was initially reported to the World Health Organization (WHO) in September 2012 (1,2). By November 11, 2013, a total of 153 laboratory-confirmed cases [...]

Published
2014
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31. Antibodies against MERS Coronavirus in dromedaries, United Arab Emirates, 2003 and 2013

Author

Meyer, Benjamin, Muller, Marcel A., Corman, Victor M., Reusken, Chantal B.E.M., Ritz, Daniel, Godeke, Gert-Jan, Lattwein, Erik, Kallies, Stephan, Siemens, Artem, van Beek, Janko, Drexler, Jan F., Muth, Doreen, Bosch, Berend-Jan, Wernery, Ulrich, Koopmans, Marion P.G., Wernery, Renate, and Drosten, Christian

Subjects
Viral antibodies -- Health aspects -- Analysis, Antibodies -- Health aspects -- Analysis, Health
Abstract

Middle East respiratory syndrome coronavirus (MERSCoV) is an emerging pathogen associated with severe respiratory symptoms and renal failure in infected patients (1,2). Globally, 156 laboratory-confirmed cases of infection with MERS-CoV, [...]

Published
2014
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32. Replicative capacity of MERS coronavirus in livestock cell lines

Author

Eckerle, Isabella, Corman, Victor M., Muller, Marcel A., Lenk, Matthias, Ulrich, Rainer G., and Drosten, Christian

Subjects
Severe acute respiratory syndrome -- Health aspects, Livestock -- Health aspects, Health
Abstract

Coronaviruses (CoV) in the genera Alphacoronavirus and Betacoronavirus (order Nidovirales, family Coronaviridae, subfamily Coronavirinae) infect a broad range of mammals, including humans (1). The human CoVs (HCoVs) HCoV-HKU1, HCoV-229E, HCoV-NL63, [...]

Published
2014
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33. Early introduction and delayed dissemination of pandemic influenza, Gabon

Author

Lekana-Douki, Sonia Etenna, Mouinga-Ondeme, Augustin, Nkoghe, Dieudonne, Drosten, Christian, Drexler, Jan Felix, Kazanji, Mirdad, and Leroy, Eric M.

Subjects
Epidemics -- Gabon -- Health aspects, Influenza -- Health aspects, Public health -- Health aspects, Health
Abstract

In April 2009, a pandemic strain of influenza A (H1N1) (pH1N1) virus emerged in Mexico and the United States; the World Health Organization declared a pandemic alert on June 11, [...]

Published
2013
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34. Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

Author

Annan, Augustina, Baldwin, Heather J., Corman, Victor Max, Klose, Stefan M., Owusu, Michael, Nkrumah, Evans Ewald, Badu, Ebenezer Kofi, Anti, Priscilla, Agbenyega, Olivia, Meyer, Benjamin, Oppong, Samuel, Sarkodie, Yaw Adu, Kalko, Elisabeth K.V., Lina, Peter H.C., Godlevska, Elena V., Reusken, Chantal, Seebens, Antje, Gloza-Rausch, Florian, Vallo, Peter, Tschapka, Marco, Drosten, Christian, and Drexler, Jan Felix

Subjects
Bats -- Diseases and pests -- Research, Coronaviruses -- Physiological aspects -- Distribution -- Research, Company distribution practices, Health
Abstract

Coronaviruses (CoVs) are enveloped viruses with a positive-sense, single-stranded RNA genome (1). CoVs are classified into 4 genera: Alphacoronavirus, Betacoronavirus (grouped further into clades 2a-2d), Gammacoronavirus, and Deltacoronavirus. Two human [...]

Published
2013
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35. Human parvovirus 4 in nasal and fecal specimens from children, Ghana

Author

Drexler, Jan Felix, Reber, Ulrike, Muth, Doreen, Herzog, Petra, Annan, Augustina, Ebach, Fabian, Sarpong, Nimarko, Acquah, Samuel, Adlkofer, Julia, Adu-Sarkodie, Yaw, Panning, Marcus, Tannich, Egbert, May, Jurgen, Drosten, Christian, and Eis-Hubinger, Anna Maria

Subjects
Parvovirus infections -- Risk factors -- Research -- Diagnosis, Children -- Health aspects, Disease transmission -- Research, Health
Abstract

Nonparenteral transmission might contribute to human parvovirus 4 (PARV4) infections in sub-Saharan Africa. PARV4 DNA was detected in 8 (0.83%) of 961 nasal samples and 5 (0.53%) of 943 fecal [...]

Published
2012
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36. Cosavirus infection in persons with and without gastroenteritis, Brazil

Author

Stocker, Andreas, Souza, Breno Frederico de Carvalho Dominguez, Ribeiro, Tereza Cristina Medrado, Netto, Eduardo Martins, Araujo, Luciana Oliveira, Correa, Jefferson Ivan, Almeida, Patricia Silva, de Mattos, Angela Peixoto, Ribeiro, Hugo da Costa, Jr., Pedral-Sampaio, Diana Brasil, Drosten, Christian, and Drexler, Jan Felix

Subjects
Medical research -- Health aspects, Medicine, Experimental -- Health aspects, Gastroenteritis -- Health aspects, RNA -- Health aspects, HIV patients -- Health aspects, Health
Abstract

The family Picornaviridae comprises 12 genera and includes several leading pathogens affecting human and animal health, e.g., foot-and-mouth-disease virus and polioviruses. With the advent of metagenomics, 3 novel human picornaviruses [...]

Published
2012
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37. Aichi virus shedding in high concentrations in patients with acute diarrhea

Author

Drexler, Jan Felix, Baumgarte, Sigrid, de Souza Luna, Luciano Kleber, Eschbach-Bludau, Monika, Lukashev, Alexander N., and Drosten, Christian

Subjects
Gastroenteritis -- Care and treatment -- Health aspects, Diarrhea -- Care and treatment -- Health aspects, Prevalence studies (Epidemiology) -- Health aspects, RNA -- Health aspects, Health
Abstract

The family Picornaviridae includes 12 established genera, and representatives of 5 of these have been found in humans (Enterovirus, Hepatovirus, Parechovirus, Cardiovirus, and Kobuvirus). Among those, human pathogenicity has been [...]

Published
2011
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38. Amplification of emerging viruses in a bat colony

Author

Drexler, Jan Felix, Corman, Victor Max, Wegner, Tom, Tateno, Adriana Fumie, Zerbinati, Rodrigo Melim, Gloza-Rausch, Florian, Seebens, Antje, Muller, Marcel A., and Drosten, Christian

Subjects
Bats -- Diseases and pests -- Genetic aspects -- Control, Viruses -- Identification and classification -- Genetic aspects -- Control, Health
Abstract

Bats (Chiroptera) constitute ≅ 20% of living mammal species and are distributed on all continents except Antarctica (1). Their ability to fly and migrate, as well as the large sizes [...]

Published
2011
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39. Dengue virus serotype 3 infection in traveler returning from West Africa to Germany

Author

Eckerle, Isabella, Kapaun, Annette, Junghanss, Thomas, Schnitzler, Paul, Drosten, Christian, and Janisch, Thomas

Subjects
Medical research, Medicine, Experimental, Medical geography -- Research, Dengue -- Case studies -- Diagnosis -- Care and treatment, Health
Abstract

To the Editor: Dengue virus (DENV) is a member of the family Flaviviridae, genus Flavivirus, and comprises 4 serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). DENV is transmitted by Aedes spp. [...]

Published
2015

40. Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana

Author

Pfefferle, Susanne, Oppong, Samuel, Drexler, Jan Felix, Gloza-Rausch, Florian, Ipsen, Anne, Seebens, Antje, Muller, Marcel A., Annan, Augustina, Vallo, Peter, Adu-Sarkodie, Yaw, Kruppa, Thomas F., and Drosten, Christian

Subjects
RNA -- Research, RNA -- Physiological aspects, Severe acute respiratory syndrome -- Causes of, Severe acute respiratory syndrome -- Research, Coronaviruses -- Health aspects, Coronaviruses -- Research
Abstract

Coronaviruses (CoVs) (order Nidovirales, family Coronaviridae, genus Coronavirus) are enveloped viruses with plus-stranded RNA genomes of 26-32 kb, the largest contiguous RNA genomes in nature (1). They are classified into [...]

Published
2009
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41. Novel human parechovirus from Brazil

Author

Drexler, Jan Felix, Grywna, Klaus, Stocker, Andreas, Almeida, Patricia Silva, Ribeiro, Tereza Cristina Medrado, Eschbach-Bludau, Monika, Petersen, Nadine, da Costa Ribeiro, Hugo, Jr., and Drosten, Christian

Subjects
Company distribution practices, Disease transmission -- Research, Picornavirus infections -- Causes of, Picornavirus infections -- Diagnosis, Picornavirus infections -- Distribution, Picornavirus infections -- Control, Prevalence studies (Epidemiology)
Abstract

Human parechoviruses (HPeVs) were detected by reverse transcription-PCR in 16.1% of 335 stool samples from children ********** The human parechovirus (HPeV) species are small, nonenveloped RNA viruses that belong to [...]

Published
2009

42. MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997

Author

Muller, Marcel A., Corman, Victor Max, Jores, Joerg, Meyer, Benjamin, Younan, Mario, Liljander, Anne, Bosch, Berend-Jan, Lattwein, Erik, Hilali, Mosaad, Musa, Bakri E., Bornstein, Set, and Drosten, Christian

Subjects
Viral antibodies -- Health aspects, Antibodies -- Health aspects, Health
Abstract

Since 2012, a newly emerged human pathogenic coronavirus (CoV) has caused an ongoing epidemic on the Arabian Peninsula. The designated Middle East respiratory syndrome (MERS)-CoV belongs to the Betacoronavirus genus [...]

Published
2014
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43. Circulation of 3 lineages of a novel Saffold cardiovirus in humans

Author

Drexler, Jan Felix, Luna, Luciano Kleber de Souza, Stocker, Andreas, Almeida, Patricia Silva, Ribeiro, Tereza Cristina Medrado, Petersen, Nadine, Herzog, Petra, Pedroso, Calia, Huppertz, Hans Iko, da Costa Ribeiro, Hugo, Jr., Baumgarte, Sigrid, and Drosten, Christian

Subjects
Gastroenteritis -- Risk factors, Gastroenteritis -- Diagnosis, Gastroenteritis -- Research, Viruses -- Identification and classification, Viruses -- Health aspects, Viruses -- Research, Genetic screening -- Methods, Genetic screening -- Health aspects
Abstract

Cardioviruses cause serious disease, mainly in rodents, including diabetes, myocarditis, encephalomyelitis, and multiple sclerosis-like disseminated encephalomyelitis. Recently, a human virus isolate obtained 25 years ago, termed Saffold virus, was sequenced [...]

Published
2008

44. Detection and prevalence patterns of group I coronaviruses in bats, Northern Germany

Author

Gloza-Rausch, Florian, Ipsen, Anne, Seebens, Antje, Gottsche, Matthias, Panning, Marcus, Drexler, Jan Felix, Petersen, Nadine, Annan, Augustina, Grywna, Klaus, Muller, Marcel, Pfefferle, Susanne, and Drosten, Christian

Subjects
Company distribution practices, Bats -- Genetic aspects, Bats -- Research, Coronavirus infections -- Risk factors, Coronavirus infections -- Distribution, Coronavirus infections -- Research, Coronaviruses -- Genetic aspects, Coronaviruses -- Research
Abstract

We tested 315 bats from 7 different bat species in northern Germany for coronaviruses by reverse transcription-PCR. The overall prevalence was 9.8%. There were 4 lineages of group I coronaviruses [...]

Published
2008

45. Chikungunya fever in travelers returning to Europe from the Indian Ocean region, 2006

Author

Panning, Marcus, Grywna, Klaus, van Esbroeck, Marjan, Emmerich, Petra, and Drosten, Christian

Subjects
Travelers -- Health aspects, Infection -- Health aspects, Immunoglobulins -- Health aspects
Abstract

Chikungunya fever has spread through several Indian Ocean islands and India, including popular travel destinations. To compare usefulness of diagnostic tests and to understand reasons for the magnitude and severity [...]

Published
2008

46. Viral load as predictor of crimean-congo hemorrhagic fever outcome

Author

Duh, Darja, Saksida, Ana, Petrovec, Miroslav, Ahmeti, Salih, Dedushaj, Iusuf, Panning, Marcus, Drosten, Christian, and Avsic-Zupanc, Tatjana

Subjects
Polymerase chain reaction -- Usage, Hemorrhagic fever -- Diagnosis, Hemorrhagic fever -- Development and progression, Hemorrhagic fever -- Drug therapy, Disease transmission -- Evaluation, Antiviral agents -- Evaluation, Viremia -- Measurement, Viremia -- Evaluation
Abstract

We used quantitative real-time reverse transcription-PCR to measure viral load in serum from 24 patients in Kosovo who had acute Crimean-Congo hemorrhagic fever. Viral load correlated with clinical disease and [...]

Published
2007

47. Coronavirus antibodies in African bat species

Author

Muller, Marcel A., Paweska, Janusz T., Leman, Patricia A., Drosten, Christian, Grywna, Klaus, Kemp, Alan, Braack, Leo, Sonnenberg, Karen, Niedrig, Matthias, and Swanepoel, Robert

Subjects
Disease transmission -- Observations, Severe acute respiratory syndrome -- Causes of, Antibodies -- Observations, Viral antibodies -- Observations, Bats -- Health aspects, Communicable diseases -- Research, Coronaviruses -- Observations
Abstract

Asian bats have been identified as potential reservoir hosts of coronaviruses associated with severe acute respiratory syndrome (SARS-CoV). We detected antibody reactive with SARS-CoV antigen in 47 (6.7%) of 705 [...]

Published
2007

48. Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients

Author

Wolfel, Roman, Paweska, Janusz T., Petersen, Nadine, Grobbelaar, Antoinette A., Leman, Patricia A., Hewson, Roger, Georges-Courbot, Marie-Claude, Papa, Anna, Gunther, Stephan, and Drosten, Christian

Subjects
Hemorrhagic fever -- Research, Hemorrhagic fever -- Diagnosis, Hemorrhagic fever -- Care and treatment, Polymerase chain reaction -- Usage, Viremia -- Measurement, Viremia -- Research, Viremia -- Usage
Abstract

We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested [...]

Published
2007

49. MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fevers

Author

Palacios, Gustavo, Briese, Thomas, Kapoor, Vishal, Jabado, Omar, Liu, Zhiqiang, Venter, Marietjie, Zhai, Junhui, Renwick, Neil, Grolla, Allen, Geisbert, Thomas W., Drosten, Christian, Towner, Jonathan, Ju, Jingyue, Paweska, Janusz, Nichol, Stuart T., Swanepoel, Robert, Feldmann, Heinz, Jahrling, Peter B., and Lipkin, W. Ian

Subjects
Hemorrhagic fever -- Causes of, Hemorrhagic fever -- Diagnosis, Hemorrhagic fever -- Research, Polymerase chain reaction -- Analysis
Abstract

Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. [...]

Published
2006

50. SARS molecular detection external quality assurance

Author

Drosten, Christian, Doerr, Hans Wilhelm, Lim, Wilina, Stohr, Klaus, and Niedrig, Matthias

Subjects
Severe acute respiratory syndrome -- Research, Severe acute respiratory syndrome -- Testing
Abstract

Inactivated severe acute respiratory syndrome-associated coronavirus samples were used for an external quality assurance study within the World Health Organization SARS Reference and Verification Network and other reference institutions. Of [...]

Published
2004

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