1. Relationship between the Extent of Coronary Artery Disease and In-stent Restenosis in Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
- Author
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Yalçın Gökoğlan, Salim Yaşar, Uygar Cagdas Yuksel, Mustafa Koklu, Suat Görmel, Erkan Yildirim, Atila Iyisoy, Baris Bugan, Murat Celik, and Cem Barçın
- Subjects
Male ,lcsh:Internal medicine ,lcsh:Diseases of the circulatory (Cardiovascular) system ,medicine.medical_specialty ,medicine.medical_treatment ,Myocardial Infarction ,lcsh:Medicine ,Coronary Artery Disease ,Coronary Restenosis ,Coronary artery disease ,Percutaneous Coronary Intervention ,Restenosis ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,Myocardial infarction ,lcsh:RC31-1245 ,Coronary atherosclerosis ,Aged ,Retrospective Studies ,Ejection fraction ,business.industry ,lcsh:R ,Percutaneous coronary intervention ,Stent ,percutaneous coronary intervention ,stent restenosis ,Middle Aged ,medicine.disease ,Coronary arteries ,medicine.anatomical_structure ,lcsh:RC666-701 ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Objective: The pathophysiological mechanism of in-stent restenosis (ISR) is different from atherosclerosis of native coronary arteries. The aim of this study was to evaluate the relationship between ISR and the extent of coronary artery disease (CAD), and to identify other risk factors associated with ISR in ST-segment elevation myocardial infarction (STEMI) patients. Methods: A total of 372 consecutive patients presenting with first acute STEMI who were successfully treated with primary percutaneous coronary intervention within 12 hours from the onset of symptoms and who had an angiographic follow-up at 3 months were included in the study. The extent of CAD was calculated using the Gensini score. Results: The incidence of ISR observed in our group of patients was 23.4% (n=87). The mean Gensini score was significantly higher in patients with ISR when compared with group without restenosis (69 [range: 51–90] vs 42 [range: 32–61]; p
- Published
- 2017
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