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BACKGROUND. Identification of factors associated with successful quitting smoking is necessary to reduce prevalence of smoking. Our analysis assessed the association between home and workplace restrictions of smoking and chances to quit smoking among adult population of Ukraine in 2005. METHODS. Binary logistic regression analysis was used to explore the associations. Independent variables included home and workplace restrictions of smoking, sex, and age. Outcome variables measured smoking status, where cases were those respondents who stopped smoking, and controls were current daily smokers. Different regression models considered former smokers who quitted at different points in time before the interview. RESULTS. Data analysis demonstrated that, among all smokers, the odds of quitting smoking were increased by 3.4 if smoking at home was restricted, and by 1.4 in case of workplace smoking restriction. In groups of respondents who did not smoke from one to six months and from six months to one year, a significant association was found between smoking cessation and smoking restriction at home. No associations with smoking restriction in workplaces were found in models considering quitters with specific duration of non-smoking. CONCLUSIONS. Ban and restriction of smoking at home can be an important factor for quitting smoking with improved outcome of quitting if a former smoker gets support for several months. Workplace restriction may be a consequence of the fact that ex-smokers find jobs where smoking is forbidden, or create smoke-free workplaces. Because this is a voluntary process of creating clean air workplaces, before smoke-free workplaces are officially established and enforced, they cannot be a factor to influence individual behavior. [ABSTRACT FROM AUTHOR]