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Start Over Author "Muller, Ilaria" Publisher the endocrine society
8 results on '"Muller, Ilaria"'

3. Gut Microbiome Associated With Graves Disease and Graves Orbitopathy: The INDIGO Multicenter European Study

Author

Biscarini, Filippo, primary, Masetti, Giulia, additional, Muller, Ilaria, additional, Verhasselt, Hedda Luise, additional, Covelli, Danila, additional, Colucci, Giuseppe, additional, Zhang, Lei, additional, Draman, Mohd Shazli, additional, Okosieme, Onyebuchi, additional, Taylor, Pete, additional, Daumerie, Chantal, additional, Burlacu, Maria-Cristina, additional, Marinò, Michele, additional, Ezra, Daniel George, additional, Perros, Petros, additional, Plummer, Sue, additional, Eckstein, Anja, additional, Salvi, Mario, additional, Marchesi, Julian R, additional, and Ludgate, Marian, additional

Published
2023
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4. Early Follow-up of Atypical Thyroiditis Induced by SARS-CoV-2

Author

Muller, Ilaria, primary, Cannavaro, Daniele, additional, Dazzi, Davide, additional, Mantovani, Giovanna, additional, Longari, Virgilio, additional, Cuzzocrea, Marco, additional, Re, Tiziana E, additional, Gori, Andrea, additional, Arosio, Maura, additional, and Salvi, Mario Giovanni, additional

Published
2021
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5. CATS II Long-term Anthropometric and Metabolic Effects of Maternal Sub-optimal Thyroid Function in Offspring and Mothers

Author

Muller, Ilaria, primary, Taylor, Peter N, additional, Daniel, Rhian M, additional, Hales, Charlotte, additional, Scholz, Anna, additional, Candler, Toby, additional, Pettit, Rebecca J, additional, Evans, William D, additional, Shillabeer, Dionne, additional, Draman, Mohd S, additional, Dayan, Colin M, additional, Tang, Hiu K C, additional, Okosieme, Onyebuchi, additional, Gregory, John W, additional, Lazarus, John H, additional, Rees, D Aled, additional, and Ludgate, Marian E, additional

Published
2020
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6. Alemtuzumab-induced thyroid dysfunction exhibits distinctive clinical and immunological features

Author

Pariani, Nadia, Willis, Mark, Muller, Ilaria, Healy, Sarah, Nasser, Taha, McGowan, Anne, Lyons, Greta, Jones, Joanne, Chatterjee, Krishna, Dayan, Colin, Robertson, Neil, Coles, Alasdair, Moran, Carla, Jones, Joanna [0000-0003-4974-1371], Chatterjee, Krishna [0000-0002-2654-8854], Coles, Alasdair [0000-0003-4738-0760], and Apollo - University of Cambridge Repository

Subjects
Thyroid, Adult, Male, Thyroiditis, Multiple Sclerosis, Middle Aged, Thyroid Diseases, Graves Disease, Young Adult, Disease Progression, Humans, Female, Alemtuzumab, Clinical Research Articles, Retrospective Studies
Abstract

Context Alemtuzumab, a highly effective treatment for multiple sclerosis (MS), predisposes to Graves disease (GD), with a reportedly indolent course. Objective To determine the type, frequency, and course of thyroid dysfunction (TD) in a cohort of alemtuzumab-treated patients with MS in the United Kingdom. Design Case records of alemtuzumab-treated patients who developed TD were reviewed. Results A total of 41.1% (102 out of 248; 80 female and 22 male) of patients developed TD, principally GD (71.6%). Median onset was 17 months (range 2 to 107) following the last dose, with the majority (89%) within 3 years. Follow-up data (range 6 to 251 months) were available in 71 case subjects, of whom 52 (73.2%) developed GD: 10 of these (19.2%) had fluctuating TD. All 52 patients with GD commenced antithyroid drugs (ATDs): 3 required radioiodine (RAI) due to ATD side effects, and drug therapy is ongoing in 2; of those who completed a course, 16 are in remission, 1 developed spontaneous hypothyroidism, and 30 (64%) required definitive or long-term treatment (RAI, n = 17; thyroidectomy, n = 5; and long-term ATDs, n = 8). Three cases of thyroiditis and 16 cases of hypothyroidism were documented: 5 with antithyroid peroxidase antibody positivity only, 10 with positive TSH receptor antibody (TRAb), and 1 of uncertain etiology. Bioassay confirmed both stimulating and blocking TRAb in a subset of fluctuating GD cases. Conclusions Contrary to published literature, we recorded frequent occurrence of GD that required definitive or prolonged ATD treatment. Furthermore, fluctuating thyroid status in GD and unexpectedly high frequency of TRAb-positive hypothyroidism suggested changing activity of TRAb in this clinical context; we have documented the existence of both blocking and stimulating TRAb in these patients., In a retrospective analysis of alemtuzumab-induced thyroid dysfunction, Graves disease with fluctuating status that was relatively refractory to treatment and anti-TSH receptor antibody–positive hypothyroidism was recorded.

Published
2018

7. Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior

Author

Hales, Charlotte, primary, Taylor, Peter N, additional, Channon, Sue, additional, McEwan, Kirsten, additional, Thapar, Anita, additional, Langley, Kate, additional, Muller, Ilaria, additional, Draman, Mohd S, additional, Dayan, Colin, additional, Gregory, John W, additional, Okosieme, Onyebuchi, additional, Lazarus, John H, additional, Rees, D Aled, additional, and Ludgate, Marian, additional

Published
2019
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8. Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Cognition

Author

Hales, Charlotte, primary, Taylor, Peter N, additional, Channon, Sue, additional, Paradice, Ruth, additional, McEwan, Kirsten, additional, Zhang, Lei, additional, Gyedu, Michael, additional, Bakhsh, Ameen, additional, Okosieme, Onyebuchi, additional, Muller, Ilaria, additional, Draman, Mohd S, additional, Gregory, John W, additional, Dayan, Colin, additional, Lazarus, John H, additional, Rees, D Aled, additional, and Ludgate, Marian, additional

Published
2018
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