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Many useful parameters depend on nonparametric first steps. Examples include games, dynamic discrete choice, average exact consumer surplus, and treatment effects. Often estimators of these parameters are asymptotically equivalent to a sample average of an object referred to as the influence function. The influence function is useful in local policy analysis, in evaluating local sensitivity of estimators, constructing debiased machine learning estimators, in efficiency comparisons, and in formulating primitive regularity conditions for asymptotic normality, We show that the influence function is a Gateaux derivative with respect to a smooth deviation evaluated at a point mass. This result generalizes the classic Von Mises (1947) and Hampel (1974) calculation to estimators that depend on smooth nonparametric first steps. We give explicit influence functions for first steps that satisfy exogenous or endogenous orthogonality conditions. We use these results to generalize the omitted variable bias formula for regression to policy analysis for and sensitivity to structural changes. We apply this analysis and find no sensitivity to endogeneity of average equivalent variation estimates in a gasoline demand application.

Many economic and causal parameters depend on nonparametric or high dimensional first steps. We give a general construction of locally robust/orthogonal moment functions for GMM, where moment conditions have zero derivative with respect to first steps. We show that orthogonal moment functions can be constructed by adding to identifying moments the nonparametric influence function for the effect of the first step on identifying moments. Orthogonal moments reduce model selection and regularization bias, as is very important in many applications, especially for machine learning first steps. We give debiased machine learning estimators of functionals of high dimensional conditional quantiles and of dynamic discrete choice parameters with high dimensional state variables. We show that adding to identifying moments the nonparametric influence function provides a general construction of orthogonal moments, including regularity conditions, and show that the nonparametric influence function is robust to additional unknown functions on which it depends. We give a general approach to estimating the unknown functions in the nonparametric influence function and use it to automatically debias estimators of functionals of high dimensional conditional location learners. We give a variety of new doubly robust moment equations and characterize double robustness. We give general and simple regularity conditions and apply these for asymptotic inference on functionals of high dimensional regression quantiles and dynamic discrete choice parameters with high dimensional state variables.