Search

Low-valent ruthenium complexes often show intriguing and characteristic catalytic activity for novel organic transformations with high atom efficiency. The design and synthesis of novel low-valent ...

Co2(CO)8-catalyzed ring-opening carbonylation of oxiranes and oxetane smoothly proceeds with high regioselectivity under 1 atm of carbon monoxide at room temperature to give the corresponding β- and γ-siloxy amides in high yields, respectively. [(R3Si)2NR1R2]+[Co(CO)4]− is thought to be an active catalyst species and directs the high regioselectivity of the carbonylation.

Ruthenium complex-catalyzed N-heterocyclization of 2-aminopyridines with vicinal-diols offers a novel synthetic method for various imidazo[1,2-a]pyridines. For example, the reaction of 2-amino-4-methylpyridine with 1,2-cyclohexanediol in the presence of a catalytic amount of RuCl2(PPh3)3 under reflux in diglyme for 24 h afforded 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazole in 74% yield.

Indole derivatives were readily prepared from the reductive N-heterocyclization of o-nitrostyrene derivatives in the presence of a catalytic amount of PdCl2(PPh3)2–SnCl2 under carbon monoxide pressure (20 kg/cm2) at 100 °C for 16 h. With o-nitrostilbene, 2-phenylindole was obtained in 75% yield.

Ruthenium complex shows high catalytic activity for the reaction of 2-aminophenol with primary alcohols to give the corresponding 2-substituted benzoxazoles in high yields. Similarly, 2-substituted benzimidazoles are also synthesized readily by the ruthenium catalyzed reaction of 1,2-phenylenediamine with primary alcohols.

Novel organic–inorganic hybrid cages composed of a half-caged silsesquioxane skeleton and a benzene ring have been synthesized by cobalt-catalyzed intramolecular cyclotrimerization of a silsesquiox...

A series of novel thiolato-bridged titanium-ruthenium mixed metal complexes, Cp2Ti(μ-SPh)2RuClCp*, Cp2Ti(μ-SPh)2RuHCp* and [Cp2Ti(μ-SPh)2Ru(L)Cp*][PF6] (L = CH3CN, t-BuCN) are prepared.