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The purpose of this study was to evaluate the self-care assessment questionnaire that is used to study the level of self-care in healthy adults. In the first stage, the self-care assessment questionnaire was translated from English to Persian using the forward-backward method. The final Persian version was evaluated in terms of translation clarity, compliance with Iranian culture, and consistency with concepts in the original version. Subsequently, the psychometric properties of the tool were determined. During the translation and localization process, changes were made to the Persian version for a better understanding. The Cronbach's alpha coefficient of the different dimensions of the tool was within the desired range (0.782-0.924). Considering the importance and necessity of a self-care assessment questionnaire in healthy adults, a comprehensive and multidimensional questionnaire was selected and localized. This questionnaire can be used to improve the level of health and self-care. [ABSTRACT FROM AUTHOR]