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The green disposal of tailings solid waste is a problem to be solved in mine production. Cemented tailings filling stoping method can realize the dual goals of solid waste resource utilization and mined-out area reduction. However, the volume of the mined-out area of the open-pit method is larger than the filling capacity, resulting in the complex stratification of the underground backfill, and the strength of the backfill cannot meet the requirements. In this paper, according to the delamination situation, the specimens of horizontal and inclination angle layered cemented tailings backfill (LCTB) is made for a uniaxial compression test, and the failure process of delamination backfill is reduced by PFC. The results show that the corresponding reduction factor φ of horizontal LCTB is 0.560-0.932, and the corresponding φ value of inclination angle LCTB is 0.338-0.772. The failure mode of backfill in different layers is mainly manifested as a tensile failure. The PFC numerical simulation results are consistent with laboratory test results, which verifies the correctness of backfill failure. The research results provide a reliable theoretical basis for the strength design of backfill in goaf, which is of great significance for solid waste utilization and environmental protection. [ABSTRACT FROM AUTHOR]