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Background: The aim of our study was to compare implant survival rates of different total hip arthroplasty (THA) bearings in the Nordic Arthroplasty Register Association., Methods: All conventional primary THAs performed between 2005 and 2017 in patients aged more than 55 years who had primary osteoarthritis were studied. Metal-on-highly cross-linked polyethylene (MoXLP), ceramic-on-highly cross-linked polyethylene (CoXLP), ceramic-on-ceramic (CoC), and metal-on-metal (MoM) bearings were included. The outcome was a revision. Kaplan-Meier (KM) estimates were calculated at 5 and 10 years. The risk for revision was analyzed using a flexible parametric survival model adjusted for nation, age, sex, femoral head size, and femoral fixation., Results: A total of 158,044 THAs were included. The 5-year KM estimates were 95.9% (95% confidence interval [CI] 95.8 to 96.1) in MoXLP, 95.8% (95% CI 95.6 to 96.1) in CoXLP, 96.7% (95% CI 96.4 to 97.0) in CoC, and 93.9% (95% CI 93.5 to 94.4) in MoM. The 10-years KM estimates were 94.2% (94.0 to 94.5) in MoXLP, 94.3% (93.9 to 94.8) in CoXLP, 95.4% (95.0 to 95.9) in CoC, and 85.5% (84.9 to 86.2) in MoM. Compared with MoXLP, the adjusted risk for revision was lower in CoC (hazard ratio [HR] 0.6, CI 0.5 to 0.6), similar in CoXLP (HR 1.0, CI 0.9 to 1.0), and higher in MoM (HR 1.3, CI 1.2 to 1.4)., Conclusions: We found that MoXLP, CoXLP, and CoC bearings evinced comparably high implant survival rates up to 10 years, and they can all be regarded as safe options in this patient group. The MoM bearings were associated with clearly lower survivorship. The CoC bearings had the highest implant survival and a lower adjusted risk for revision compared with highly cross-linked polyethylene bearings., (Copyright © 2024 Elsevier Inc. All rights reserved.)

Early designs of uncemented hip implants turned out to be failures mainly because the prerequisites for durable implant fixation were unknown. One exception was the chrome-cobalt stem of the Madreporic Lord prosthesis. We prospectively studied this prosthetic design in 107 hips that underwent surgery in 1979-1986. At the last follow-up, five stems and 54 cups had been revised, corresponding to stem and cup survival rates of 92%±3% and 45%±5% at 26years. In all, 66 hips with remaining Lord stems were available for clinical follow-up 26years (24-29) after the index operation. The mean total Harris hip and pain scores were 81 (SD 14) and 41 (SD 5)., (Copyright © 2013 Elsevier Inc. All rights reserved.)

This study was designed to estimate direct and indirect costs incurred by hip disease in patients eligible for total hip arthroplasty (THA). Before THA, 2635 patients completed a questionnaire regarding the use of resources because of their hip disease. Costs were assigned using official statistical sources or market prices. Annual costs amounted to US$ 7666 per patient. In a regression analysis, higher annual costs were associated with working age, female gender, comorbidity, and operation waiting time more than 90 days (P < .005). The burden of disease for THA candidates is extensive, where loss of productivity is the principal cost. Long wait for surgery is associated with increased costs. This study provides baseline cost data, which will be useful for further health economic analyses and could provide guidance for health care decision makers., (Copyright © 2012 Elsevier Inc. All rights reserved.)

Thirty-eight patients (40 hips) randomly received either an uncemented fully porous-coated composite stem (Epoch; Zimmer, Warsaw, Ind) or an uncemented proximally porous-coated solid stem (Anatomic; Zimmer). Patients were followed up for 7 years using radiostereometry, dual-energy x-ray absorptiometry, conventional radiography, the Harris Hip Score, and a pain questionnaire. Both stem designs achieved excellent outcome for fixation (stem subsidence and stem rotations close to zero) and clinical outcome, without any difference between the 2 groups (P > .12). Median wear rates were low despite use of conventionally gamma-sterilized polyethylene. No stem was radiographically loose on the postoperative radiographs. The low-modulus composite stem had positive effects on early proximal bone remodeling in Gruen regions 1, 2, 6, and 7 (P < .04). However, at 7 years, this bone-sparing effect persisted in only the calcar region (Gruen region 7)., (Copyright © 2012 Elsevier Inc. All rights reserved.)

Eighty patients (84 hips) randomly received an anteverted cobalt-chromium stem (Lubinus SP2; Waldemar Link, Hamburg, Germany) with matte, polymethyl methacrylate-coated, or polished surface (uncollared). Radiostereometry was used to study migration and wear; and the bone mineral density was studied with dual-energy x-ray absorptiometry at 6 months, 1 year, 2 years, and 5 years. The polished stems had subsided 0.1 to 0.2 mm more at 6 months and 0.3 to 0.4 mm more at 5 years than the matte and precoated versions (P < .0001) and subsided mainly inside the cement mantle. The rotations of the stem and the migration and wear of the cemented cup did not differ between the 3 groups. After 1 and 2 years, the polished stems had lost significantly less bone mineral in Gruen zones 1, 2, 6, and 7 (P = .004 to .03); but this difference had disappeared after 5 years. The period of improved bone remodeling around the polished version coincided with the early period of increased subsidence, suggesting that stem motions inside the mantle resulted in a favorable loading of the proximal femur. Our observations suggest that alternative shapes could be possible on future polished femoral stem designs., ((c) 2010 Elsevier Inc. All rights reserved.)

The influence of articulating surface design of AMK total knee prosthesis (DePuy, Johnson & Johnson) on migration and radiographic outcome at 5 years was evaluated. The knees were randomly allocated to receive a flat or a concave insert with retention of the posterior cruciate ligament when preoperative deformity was less severe and either a concave or a posterior-stabilized insert with resection of the posterior cruciate ligament when deformity was more pronounced. In 64 knees, migration was measured with radiostereometry. The posterior-stabilized component displayed more varus-valgus tilting than the concave insert. Other statistically significant differences in migration were not seen. Radiolucent lines were frequently seen without differences between prosthesis groups.

Ninety patients (97 hips) scheduled for total hip arthroplasty were stratified to fixation of the femoral component using fluoride-containing cement or Palacos with gentamicin. Whole polyethylene Reflection and press-fit Trilogy cups were used. All patients received Spectron EF stem. The micromotions of the stem were measured with radiostereometric analysis and the periprosthetic bone mineral density with automatic and manual dual-energy x-ray absorptiometry (DEXA) analysis. At 2 years, the choice of cement did not influence the subsidence or rotations of the stem. The DEXA analysis revealed more loss of periprosthetic bone mineral density in fluoride cement group. We speculate that forming of fluorapatite crystals, toxic effects of the fluoride, or lower radiopacity of the fluoride cement might explain this finding. According to our study with 2-year of follow-up, there is no obvious advantage of addition of fluoride to acrylic bone cement when used to fixate the femoral component in total hip arthroplasty.

The radiographs of 46 consecutive polyethylene cups used in cemented first-time revision of the acetabulum were studied up to a mean of 10.7 years (range, 0.5-16.3 years). Six cups developed loosening, of which 2 were revised. New radiolucent lines appeared mainly up to the 3 years follow-up. Progression of radiolucencies to new regions was noted in 28 (61%) cups. This progression occurred as an increase in extension from the periphery to the central region of the interface, whereas the width only showed minor changes. Our findings indicate that even radiolucent lines with a width <1.0 mm should be given attention because these lines can surround the cup before significant migration (>5 mm) is established. True lateral radiographs exposed to visualize the interface add information concerning presence of loosening. According to our opinion, complete radiolucent lines on either the anterior-posterior or lateral view, with a width of 0.3 to 0.5 mm or more, should be regarded as radiographic failure.

Forty-six consecutive polyethylene cups used in cemented first-time revision of the acetabulum were evaluated at repeated occasions up to mean 10.7 years (range, 0.5-16.3 years). At the last follow-up, 3 cups had been revised (6.5%), 2 because of loosening and 1 because of fracture of the acetabulum. Furthermore, 4 were radiographically loose, corresponding to a radiographic loosening rate of 13% and a mechanical failure rate (revision or radiographic loosening) of 15.2%. Presence of rheumatoid arthritis was the only predictor of mechanical failure (relative risk [RR] = 7.7, 95% confidence limits, 1.7-36.2; P =.002). In patients without rheumtoid arthritis, there was only 1 (2.6%) revision and 3 of 39 cases (7.7%) with mechanical failure. Recementation of a Charnley cup in first-time revisions results in a low failure rate in an elderly, nonrheumatoid arthritis population with small or moderate bone deficiencies.

In a prospective, randomized study, patients with medial gonarthrosis stage I to III according to Ahlbäck were allocated to a unicondylar knee arthroplasty (Miller-Galante, Zimmer, Inc., Warsaw, IN) with an all-polyethylene tibial component or metal-backed tibial component of the same design. The purpose of the study was to evaluate if metal backing enhanced tibial component fixation. A total of 45 knees (42 patients; 23 metal-backed components and 22 all-polyethylene components) were examined. We used radiostereometric analysis to measure micromotion of the tibial component over a period of 2 years after surgery. Hospital for Special Surgery score was used for clinical evaluation. We found no statistically significant differences in clinical results or migration of the tibial component over a 2-year follow-up period. These findings do not support better fixation of metal-backed tibial components. Because of these findings, we advocate all-polyethylene tibial components in unicondylar knee arthroplasties because of optimal biomechanical strength at a given height of tibial component, avoiding potential problems of modularity and minimizing the amount of interfaces, at a lower cost.

Forty-seven knees in 43 patients with severe deformities randomly received AMK total knee arthroplasty with concave (C, n = 25) or posterior-stabilized (PS, n = 22) polyethylene insert and with resection of the posterior cruciate ligament. Radiostereometric examinations were done postoperatively and after 3, 12, and 24 months. Two patients (1 C, 1 PS) underwent revision surgery. At the 2-year follow-up, the median absolute rotations of the tibial inserts ranged from 0.13 degrees to 0.26 degrees (C vs PS; P =.1-.7). The maximum total point motion was almost identical in the 2 groups (C, 0.38; PS, 0.39; P =.9). Maximum subsidence, lift-off, and Hospital for Special Surgery scores did not differ (P =.1-.6). Recipients of 20 of 24 knees with concave design and 14 of 19 knees with posterior-stabilized design reported that their knee could be regarded as normal or almost normal. Variations of the configuration of the polyethylene insert did not alter the outcome in the short term.

The micromotions of femoral stems cemented into impacted bone-graft were studied in 23 femora from adult sows. The model was validated against 2 patient groups. Conventional impaction technique and a new impaction technique using polished and rotating impactors were studied in the preclinical model and in 14 and 10 patients with type II defects. The specimens were loaded in an MTS (Minneapolis Testing System) machine for 72,000 cycles at 250N to 3,250N. The bone-graft was rinsed in tepid water, and most of the bone marrow and fat were removed. Radiostereometric measurements revealed small subsidence of the stems cemented into the specimens and the patients 6 weeks after the operation without any difference (median values, -0.06 to -0.16 mm). Further studies of specimens operated with nontreated bone-graft showed that extraction of fat increased the stability. Our findings suggest that the early postoperative implant stability after impaction grafting of the femur mainly is an effect of surgical technique and graft treatment. The new impaction technique, with which we hoped to obtain a more reproducible procedure and less risk for perioperative fracture, resulted in stability equal to that obtained with the conventional technique.

A total of 51 knees (45 patients) with osteoarthrosis were stratified in a randomized study to receive a hydroxyapatite-coated Freeman-Samuelson (FS HA) or a porous-coated Miller-Galante II (MG II) uncemented total knee arthroplasty. Repeated clinical, radiographic, and radiostereometric analysis (RSA) evaluations of the tibial components were done for 5 years. The clinical outcome was equal at the 5-year follow-up (mean Hospital for Special Surgery score, 93). Standard radiographs displayed more zones around the tibial stem in the MG II group. RSA revealed that the FS HA components migrated less (smaller maximum total point motion and maximum subsidence) after 5 years and showed less inducible displacements at the 1-year follow-up. The stability of the implants obtained is equal to or better than cemented implants after 5 years. Key words: knee prosthesis, cementless, hydroxyapatite, radiostereometry, inducible displacement.

In a prospective, consecutive study of first-time cemented femoral revisions, 109 hips were evaluated for a minimum of 7 years. There were 87 Charnley (18 standard, 69 long), 21 Spectron (3 standard, 18 long), and 1 Brunswick long-stem arthroplasties. There was an increased risk for rerevision in younger patients (P = .0001) and with use of standard stems (P = .002). Factors of importance for development of mechanical failure were younger age (P = .0001), presence of more pronounced bone defects (P < .005), use of standard stems (P < .0005), and presence of radiolucencies on the postoperative radiographs (Gruen zones 4 and 6) (P < .01). Our results confirm that cemented femoral revisions are a durable option in elderly patients, when improved cementing techniques and long-stem prostheses are used.

Sixty-two patients (64 hips) were provided with porous press-fit cups (Trilogy), plasma-sprayed with a coating consisting of 70% hydroxyapatite and 30% tricalcium phosphate. The patients were randomized to a cup with cluster holes for adjunctive screw fixation (n = 30) or to a cup without holes (n = 34). Radiostereometry was used to study migration and wear. Up to 2 years median translations and rotations <0.2 mm and <0.2 degrees were recorded in the 2 groups, without any difference. The median annual proximal wear (0.11 and 0.12 mm) was within the expected range despite the use of a ceramic coating, and it did not differ between the 2 designs. Radiolucent lines were frequently seen postoperatively but diminished during the follow-up without any sign of migration into the gaps. At 2 years, the median Harris scores were 99 points (range, 51-100 points) in the group with and 98 points (range, 69-100 points) in the group without screws. The results indicate that early fixation can be achieved for ceramic-coated press-fit cups without using additional screw fixation.

Migration, wear, and presence of radiolucencies were studied in 23 matched pairs of patients operated with porous-coated acetabular cups with additional screw fixation. All implants had the same type of titanium fiber mesh. In each pair, one of the cups was plasma-sprayed with a coating consisting of 70% hydroxylapatite (HA) and 30% tricalcium phosphate (TCP). Radiostereometric analysis up to 2 years after the operation revealed smaller rotations around the horizontal axis in cups with HA/TCP coating. The migration of the cup center was not significantly influenced. Evaluation of femoral head penetration in 12 of the matched pairs did not reveal any significant difference. Immediately after operation, implants with HA/TCP coating had more central radiolucencies, which, despite minimal migration, disappeared during the follow-up. The clinical results did not differ between the 2 groups. The findings of less tilting and diminishing radiolucencies in the cups with HA/TCP coating suggest a more complete ingrowth of bone and a better sealing of the interface.

Fifty-three consecutive patients (57 knees; mean age, 69 years) entered a prospective randomized study to compare the fixation of hydroxyapatite (HA)-coated (29 knees) with cemented (28 knees) tibial components in the Tricon II total knee arthroplasty. The quality of the fixation during 5 years postoperatively was evaluated with radiostereometric analysis (RSA). Three HA-coated implants were revised: 2 owing to infection, and 1 owing to early delamination of the coating and clinical loosening. Eight patients (9 knees) died, 1 patient sustained a stroke, and 1 patient refused investigations after 1 year. In the 40 patients (19 HA-coated, 21 cemented) remaining at 5 years, the magnitude of the micromotion between the HA-coated and cemented groups did not differ. The HA-coated implants displayed most of the migration within the initial 3 months then stabilized, whereas the cemented implants showed an initially lower, but over time continuously increasing migration. Between 1 and 2 years, 4 of 24 HA-coated and 10 of 23 cemented implants migrated >0.2 mm and were categorized unstable, which has been shown to have a prognostic value as regards future aseptic loosening. Progressive radiolucent lines developed in 2 cemented knees, which both were categorized unstable. If HA-coated implants can sustain the forces that threaten the fixation in the early period after implantation, a strong and enduring fixation may be obtained.

Forty uncemented total knee arthroplasties (36 patients) were randomly allocated to a Miller-Galante II prosthesis with or without hydroxyapatite/tricalcium phosphate (HA/TCP) coating on the titanium fiber mesh on the undersurface of the tibial component. The patients were followed for 2 years with repeated radiostereometric examinations. After 2 years, the HA/TCP tibial components displayed smaller anterior-posterior tilt and less subsidence. The mean value of maximal total point motion was small: 0.5 mm in both groups. At 24 months, there were more radiolucent lines under the tibial tray and around the stem in the uncoated group, but the clinical results did not differ. HA/TCP coating on the undersurface of the tibial component improved the stability and seemed to improve the quality of the interface between the tibial component and the bone.

Screw-fixated and hydroxyapatite-coated press-fit cups were studied using radiostereometry in 29 revision and 14 primary arthroplasties. The acetabular defects in the revision cases varied from none to type 3 (wall defects) according to Gustilo-Pasternak. Morsellized allograft was used in 25 revisions. Nine of these cups rested on less than 50% living bone. After 2 years, the mean migration in the revised group reached 0.36, 0.21, and 0.49 mm in the horizontal, longitudinal, and anteroposterior (AP) directions. The mean rotations varied between 0.5 degrees and 0.7 degrees depending on direction. The primary implants displayed smaller mediolateral migration and AP tilt. The mean proximal wear rate for the whole group was 0.11 mm/y. A central gap on the postoperative AP view implied less migration. The size of the preoperative bone defects or amount of bone-graft used had no influence on the migration. Despite extensive use of morsellized allograft, this implant displayed the smallest migration so far reported in revision hip arthroplasty.

One hundred twenty patients (22 men, 98 women; 144 knees) with uncemented Freeman-Samuelson total knee arthroplasty were followed prospectively. Eighty-one patients had rheumatoid arthritis and 39 patients had osteoarthrosis. The mean follow-up period was 6.8 years. Three different types of tibial components were used: a high-density polyethylene component without stem, a metal-backed tibial component without stem, and a metal-backed tibial component with stem. Progressive varus tilting turned out to be an early sign of failure and occurred in 22% of the tibial components. Revision of the tibial component was done in 17 knees. Survival analysis with revision as endpoint revealed a survival rate of 79% at a follow-up period of 10 years. Cementless fixation of this design using macrointerlocking pegs and no other stabilization resulted in poor fixation and a high revision rate and cannot be recommended.

Four hundred ninety-four patients (539 hips) with a mean age of 50.1 (SD, 9.7) years entered a prospective, multicenter study of the Porous Coated Anatomic (Howmedica, Rutherford, NJ) total hip arthroplasty. The preoperative diagnoses were primary osteoarthrosis (297 hips), secondary osteoarthrosis to childhood diseases (88 hips), fracture (73 hips), inflammatory arthritis (26 hips), idiopathic avascular necrosis (28), and miscellaneous (27 hips). After a mean follow-up period of 6 years and 10 months, 71 hips had been revised. The mean Harris hip score increased from 43 (15.7) to 94 (7.4) at the last follow-up evaluation, without any deterioration with time. After 7 years, the combined survival rate for the cup and/or stem using revision as endpoint was 92.2%. Radiographic failure, defined as migration of either component more than 5 min and/or focal osteolysis, was registered in 72 stems and 96 cups. The combined clinical (revision) and radiographic 7-year survival rates were 61.1 (+/-5.2) and 59.7 (+/-5.3) for the stem and cup, respectively. Statistical analysis revealed that young age and poor fill rate influenced the rate of stem failure, whereas cup failure was difficult to predict. Four variables were associated with stem subsidence: loosening of beads, pedestal formation, sclerotic lines in Gruen zone 7, and acetabular granuloma. According to our findings, the 5- to 10-year complication rate with this implant is high. Therefore, continuous radiographic follow-up evaluation of these cases is strongly recommended, to enable revision before severe destruction of bone or catastrophic clinical failure has occurred.

The migration of 60 press-fit cups fixed with screws was evaluated by radiostereometric analysis for 2 years in 57 patients revised because of aseptic loosening. The mean proximal migration of the cup center increased continuously up to 0.36 mm (range, 0.0-1.6 mm), whereas the migration in the other directions reached a level at 0.3 to 0.4 mm after 6 months. Mean rotations of less than 1 degree were recorded. Factors influencing motions were cup size, use of bone-grafts, and position of the cup center in the vertical and horizontal directions. Compared with previous stereoradiographic studies of cemented revisions, the migration of the press-fit cup was smaller, however, still higher than previously reported for uncemented cups of the same design used in primary surgery.

Twenty-six women and three men (34 knees) with osteoarthrosis were operated with the Miller-Galante I (Zimmer, Warsaw, IN) knee prosthesis. The patients were randomized to either cemented or uncemented fixation of the tibial component. All patients received a TiVaAl alloy tibial plate with four pegs and titanium fiber-mesh undersurface. In the uncemented knees four screws were added. The fixation of the tibial component was determined by roentgen stereophotogrammetric analysis during the first 2 postoperative years. Rotations of the entire tibial component were recorded, as well as proximal or distal translation of various parts of the prosthetic edge corresponding to subsidence and lift-off. The uncemented components displayed almost all rotation and translation during the first 6 weeks, whereas the cemented ones displayed a more gradually increasing migration during the 2 years. Tibial component rotation about the sagittal axis was significantly increased in the uncemented knees throughout the investigation period. This corresponded to increased subsidence medially or laterally in the uncemented knees, whereas lift-off was equal in the two groups. Thin (8.5 mm) uncemented tibial components displayed more subsidence than the thicker ones at the medial or lateral edge 3 months after surgery.

The authors evaluated the fixation of cemented acetabular prostheses in patients with osteoarthritis (20 hips), rheumatoid arthritis (15 hips), and sequelae after fracture of the femoral neck (13 hips) using roentgen stereophotogrammetric analysis. The three-dimensional displacements of the cups were measured during the first 2 postoperative years, and radiographs were examined to assess bone quality, containment, inclination, and area of cement surrounding the cups. There was a greater proportion of migrating cups in patients with rheumatoid arthritis and fracture of the femoral neck compared with osteoarthritis. Patients with poor bone quality according to the modified Engh index, small cement area surrounding the cups, and cups with small inclination displayed increased frequency of migration.

Twenty-four patients (25 knees) with osteoarthrosis (OA) and 19 patients (20 knees) with rheumatoid arthritis (RA) were operated with bi-tricompartmental knee arthroplasty. The patients were randomized to cemented or cementless fixation of the tibial component. The fixation of the tibial components was examined with roentgen stereophotogrammetric analysis (RSA) up to 24 months after operation. The following parameters representing tibial component micromotion were measured: (1) maximum migration of the prosthetic edge (maximum total point motion, MTPM); (2) distal migration of the prosthetic center (subsidence); (3) maximum proximal movements of the prosthetic edge ("lift-off"); and (4) prosthetic rotations, corresponding to internal/external rotation, adduction/abduction, and forward/backward tilt of the tibial component. All prostheses displayed significant micromotions, which tended to decrease 3-6 months after the operation. The average migration after 2 years, when measured as maximum single axis rotation, and MTPM were about 0.9 degrees-1.5 degrees and 1.0-1.5 mm, respectively, in all four groups. There were no statistically significant differences between cemented and cementless prostheses in either the OA or the RA group. The fixation in the RA patients did not significantly differ from that of the OA patients, perhaps because the RA patients had lower weight and were living a more sedentary life.

The primary migration of 15 and 22 cemented acetabular and femoral prosthetic components was recorded in 23 patients operated because of type I (minimal endosteal bone loss) and type II (thinning of bone, enlargement of femoral canal and acetabulum) mechanical loosening. Roentgen stereophotogrammetric analysis was used to measure the three-dimensional displacements of the center of the acetabulum and the femoral head. All but 1 of the acetabular and 1 of 15 revised femoral stem prostheses migrated within 2 years after the operation, whereas 5 of 7 revised femoral surface arthroplasties were stable. Femoral components with type II loosening migrated, on average, 1.5 mm (range, 0.6-3.0 mm) during the first postoperative year, compared with 0.7 mm (range, 0.3-1.1 mm) in patients with type I loosening (P less than .02). Increased bone loss of the acetabulum (type II), the quality of the bone-cement interface as judged from radiographs, and the presence of perforation of the femoral cortex did not significantly influence the rate of migration in this group. Compared with previously presented studies of cemented primary hip prostheses, cemented revisions seem not only to migrate more frequently but also at a higher rate. Poor primary fixation is probably one important cause of the high frequency of clinical failures in these patients.