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This special issue targets an audience of scholars and practitioners across the globe to advance research, enhance practice, and facilitate policy-making decisions among those interested in emulating and/or learning from US intercollegiate athletics. We begin with a panel of practitioners and academics who comment directly on the discussion of the globalization of intercollegiate athletics. Together with the articles included in this issue, those interested in the advancement, fortification, reform, and development of global intercollegiate athletics can draw upon a variety of critical perspectives and hundreds of years of combined experience in the field. Panelists in this dialogue include a variety of experiential lenses, institutional affiliations, and oversight responsibilities. Current and former titles include those of coach, president/chancellor, director of athletics, professor, senior woman administrator, faculty athletics representative, consultant, and NCAA chief executive officer. Through these lenses, our panelists tackle questions that emerged through foundational literature and global dialogue. 尽管美国的校际体育运动极具特色, 许多国家正计划着在自己的市场中建立校际体育系统。因此, 与《全球体育管理杂志》内容相一致, 本期特刊着眼于全球学者和从业者, 以推进实践研究, 促进良好的决策制定。基于此目标, 我们与从业者和专家学者直接就校际体育全球化进行讨论。对全球校际体育运动的进步、强化、改革和发展感兴趣的学者和从业者可以借鉴本期特刊文章中各种批判性观点以及在该领域积淀了数百年的综合经验。本次访谈邀请到的讨论组成员来自于各行各业, 经验丰富, 现任或曾任体育教练、校长、体育主任、教授、资深女性管理人员、教师代表、体育顾问以及全国大学生体育协会首席执行官等。凭借他们多年积累的经验, 本期讨论组将致力于通过基础文献和全球对话解决问题。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Global Sport Management is the property of the Global Alliance of Marketing & Management Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. (Copyright applies to all Abstracts.)

Drugs such as linezolid that inhibit bacterial protein synthesis may be beneficial in treating infections caused by toxigenic Staphylococcus aureus. As protein synthesis inhibitors have no effect on preformed toxins, neutralization of pathogenic exotoxins with anti-toxin antibodies may be beneficial in conjunction with antibacterial therapy. Herein, we evaluated the efficacy of humanmouse chimeric high-affinity neutralizing anti-staphylococcal enterotoxin B (SEB) antibodies in the treatment of experimental pneumonia caused by SEB-producing S. aureus. Since HLA class II transgenic mice mount a stronger systemic immune response following challenge with SEB and are more susceptible to SEB-induced lethal toxic shock than conventional mice strains, HLA-DR3 transgenic mice were used. Lethal pneumonia caused by SEB-producing S. aureus in HLA-DR3 transgenic mice was characterized by robust T cell activation and elevated systemic levels of several pro-inflammatory cytokines and chemokines. Prophylactic administration of a single dose of linezolid 30 min prior to the onset of infection attenuated the systemic inflammatory response and protected from mortality whereas linezolid administered 60 min after the onset of infection failed to confer significant protection. Human-mouse chimeric high-affinity neutralizing anti-SEB antibodies alone, but not polyclonal human IgG, mitigated this response and protected from death when administered immediately after initiation of infection. Further, anti-SEB antibodies as well as intact polyclonal human IgG, but not its Fab or Fc fragments, protected from lethal pneumonia when followed with linezolid therapy 60 min later. In conclusion, neutralization of superantigens with high-affinity antibodies may have beneficial effects in pneumonia. [ABSTRACT FROM AUTHOR]

Tests the hypothesis that adding haptic to visual information facilitates discrimination of three-dimensional objects on more difficult problems among kindergarten children.