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Compares desmopressin responders and non-responders with respect to pharmacokinetics and renal effects of desmopressin. Absence of pharmacokinetic differences between the groups; Smaller spontaneous bladder capacity of non-responders; Less concentrated urine produced by responders; Urodynamic defect among non-responders; Osmoregulatory defect among responders.

Evaluates relationships between the bladder voiding and polysomnographic events in children suffering from enuresis. Mean latency between sleep onset and the first bladder voiding; Consideration of the enuretic events as a predominantly non-rapid eye movement sleep phenomenon.