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The purpose of this study was to examine associations between perceived neighborhood safety and mental health burdens among gay, bisexual, and other men who have sex with men (MSM) in Paris, France. Participants were recruited through a geosocial networking application (n = 580) and completed a web-based cross-sectional survey. Modified Poisson models were used to estimate risk ratios and 95% confidence intervals for the associations between perceived neighborhood safety and depression symptoms, anxiety symptoms, and psychological distress. Perceived lack of neighborhood safety was associated with depression symptoms, anxiety symptoms, and psychological distress in our sample of MSM. [ABSTRACT FROM AUTHOR]