1. Instrumental activities of daily living and mild cognitive impairment.
- Author
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Libon, David J., Emrani, Sheina, Matusz, Emily F., Wasserman, Victor, Perweiler, Elyse, Ginsberg, Terrie Beth, Powell, Leonard, Bezdicek, Ondrej, Swenson, Rodney, and Schmitter-Edgecombe, Maureen
- Subjects
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ACTIVITIES of daily living , *EPISODIC memory , *MILD cognitive impairment , *EXECUTIVE function , *NEUROPSYCHOLOGICAL tests , *CONTROL (Psychology) , *MEMORY testing - Abstract
Background: Functional impairments are a necessary requirement for the diagnosis of a dementia along with observed cognitive impairment. Comparatively, functional abilities are often relatively intact in those with mild cognitive impairment (MCI). Objective: The current research examined the associations between memory clinic participants classified as cognitively intact, amnestic MCI, and mixed/dysexecutive MCI, using Jak-Bondi criteria, and Instrumental Activities of Daily Living - Compensation Scale (IADL-C) abilities, an informant-based questionnaire that quantifies functional abilities. The associations between functional abilities as assessed with the IADL-C and performance on neuropsychological tests were also investigated. Methods: IADLC scores were obtained along with a comprehensive neuropsychological protocol on memory clinic participants (n = 100) classified as cognitively normal (CN), amnestic MCI (aMCI), or a combined mixed/dysexecutive (mixed/dys) MCI. Regression analyses were employed to determine how the IADLC related to neuropsychological test performance. Results: On the IADLC, greater functional impairment was commonly observed in the mixed/dys MCI group compared to CN participants. Furthermore, the mixed/dys MCI group had lower scores on activities such as Money and Self-Management, Travel and Event Memory subscales compared to the CN group. Linear regression analyses found greater functional impairment in relation to lower scores on executive and episodic memory tests. Conclusions: Greater functional impairment as assessed with the IADL-C appears to be disproportionately associated with dysexecutive difficulty, and to a lesser degree, episodic memory. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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