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Your search keyword '"L'henaff M"' showing total 2 results
Start Over Author "L'henaff M" Publisher taylor & francis ltd
2 results on '"L'henaff M"'

1. Coastal Ocean Forecasting: system integration and evaluation

Author

Kourafalou, V. H., De Mey, P., Le Henaff, M., Charria, Guillaume, Edwards, C. A., He, R., Herzfeld, M., Pascual, A., Stanev, E. V., Tintore, J., Usui, N., Van Der Westhuysen, A. J., Wilkin, J., Zhu, X., Kourafalou, V. H., De Mey, P., Le Henaff, M., Charria, Guillaume, Edwards, C. A., He, R., Herzfeld, M., Pascual, A., Stanev, E. V., Tintore, J., Usui, N., Van Der Westhuysen, A. J., Wilkin, J., and Zhu, X.

Abstract

Recent advances in Coastal Ocean Forecasting Systems (COFS) are discussed. Emphasis is given in the integration of the observational and modeling components, each developed in the context of monitoring and forecasting in the coastal seas. These integrated systems must be linked to larger scale systems toward seamless data sets, nowcasts and forecasts (from the global ocean, through the continental shelf and to the nearshore regions). Emerging capabilities include: methods to optimize coastal/regional observational networks; and probabilistic approaches to address both science and applications related to COFS. International collaboration is essential to exchange best practices, achieve common frameworks and establish standards.

Published
2015
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2. Factors associated with Efavirenz discontinuation in a large community-based sample of patients.

Author

Spire, B., Carrieri, P., Garzot, M.-a., L'henaff, M., Obadia, Y., and The Trt-5 Group

Subjects
MENTAL depression, DRUGS, AIDS, COMPULSIVE behavior, DEPRESSED persons, MEDICAL history taking
Abstract

Efavirenz (EFV) is a potent antiretroviral drug; its use may be limited, however, by psychiatric symptoms that require its discontinuation. We sought to identify the characteristics that placed patients at an elevated risk of discontinuation. Data for this cross-sectional study came from a self-administered questionnaire distributed by French AIDS community associations; it collected information about sociodemographic characteristics, addictive behaviours, treatment regimens, EFV history and depression. Patients remaining on EFV for more than six months were compared with those who stopped taking it. Of the 828 patients who completed the questionnaire, 175 had taken EFV for at least six months, and 152 had discontinued it (median months [IQR] of exposure=4[2-10]). Of these 327 patients (median age=42), 23% were women, 46% were unemployed, 38% had a steady sexual partner and 24% reported a history of multiple depressive episodes. Logistic regression showed that the factors independently associated with EFV discontinuation were female gender (OR[95%CI]=2.2[1.2-3.8]), unemployment (1.8[1.1-2.8]), a steady sexual partner (1.7[1-2.5]) and multiple episodes of depression (2.6[1.5-4.5]). Clinicians should keep in mind the neuropsychiatric risks of EFV during the first year, especially among patients with a history of multiple depressive episodes. [ABSTRACT FROM AUTHOR]

Published
2004
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