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We aimed to evaluate the cancer detection rates of 6-, 10-, 12-core biopsy regimens and the optimal biopsy protocol for prostate cancer diagnosis in patients with renal failure. A total of 122 consecutive patients with renal failure underwent biopsy with age-specific prostate-specific antigen (PSA) levels up to 20 ng/mL. The 12-core biopsy technique (sextant biopsy + lateral base, lateral mid-zone, lateral apex, bilaterally) performed to all patients. Pathology results were examined separately for each sextant, 10-core that exclude parasagittal mid-zones from 12-cores (10a), 10-core that exclude apex zones from 12-cores (10b) and 12-core biopsy regimens. Of 122 patients, 37 (30.3%) were positive for prostate cancer. The cancer detection rates for sextant, 10a, 10b and 12 cores were 17.2%, 29%, 23.7% and 30.7%, respectively. Biopsy techniques of 10a, 10b and 12 cores increased the cancer detection rates by 40%, 27.5% and 43.2% among the sextant technique, respectively. Biopsy techniques of 10a and 12 cores increased the cancer detection rates by 17.1% and 21.6% among 10b biopsy technique, respectively. There were no statistical differences between 12 core and 10a core about cancer detection rate. Adding lateral cores to sextant biopsy improves the cancer detection rates. In our study, 12-core biopsy technique increases the cancer detection rate by 5.4% among 10a core but that was not statistically different. On the other hand, 12-core biopsy technique includes all biopsy regimens. We therefore suggest 12-core biopsy or minimum 10-core strategy incorporating six peripheral biopsies with elevated age- specific PSA levels up to 20 ng/mL in patients with renal failure. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to assess the comparative therapeutic efficacy of traditional Chinese acupuncture. Material and Methods: During the period from January 1997 to April 1999, 50 children (23 boys, 17 girls) suffering from primary persistent nocturnal enuresis, aged 9-18 years, were included in the study. The response rate was monitored at 2 and 4 weeks, and then every 3 months by recording dry nights on a calendar. Results: The efficacy of treatment, which was expressed as a percentage of dry nights, was high. Within 6 months, 43 (86%) patients were completely dry and 2 (10%) patients were dry on at least 80% of nights. Conclusions: Treatment using acupuncture in patients with persistent enuresis nocturna appeared to be most efficacious both in terms of the percentage of dry nights at the end of treatment and in relation to the stability of results, even after the end of the study. [ABSTRACT FROM AUTHOR]

Objective: To find the efficacy and optimal dosage of oxybutynin HCl in a group of enuretic children, who were non-responsive to imipramine. Material and Methods: Thirty-six patients with enuresis who were non-responsive to imipramine were urodynamically assessed and subsequently treated with oxybutynin hydrochloride (HCl). Patients with inadequate bladder storage function (IBSF) were started on 10-mg daily oxybutynin HCl for one month. If the initial treatment was found to be inadequate, the dose was increased to 15 mg daily. The dose in patients who were non-responsive to 15-mg daily dose was increased to 20-mg daily dose. Patients who were normal urodynamically were treated with a dose of 15 mg daily for one month. Results: Before the treatment, 17 patients had IBSF (47.2%). The majority of the patients (88.2%) with IBSF were responsive to the 15-mg daily oxybutynin HCl. The treatment in patients with normal bladder function was generally unsuccessful. Conclusions: Oxybutynin HCl in sufficient dosages seems to be effective in the treatment of enuretic patients with IBSF. [ABSTRACT FROM AUTHOR]

A 75-year-old patient applied to the urology clinic with a cystocele and ultrasonography of urinary tract evidencing bilateral grade III hydronephrosis. She didn''t complain about any urination problem. Gynecologic examination showed a marked cystocele throughout its entire extension on the anterior wall of vagina. The excretory urography confirmed the presence of bilateral hydronephrosis and ''narrowing distal ureters.'' An anterior colporrhaphy and tension-free vaginal tape procedure were performed without any complication. At the third month of the follow-up, regression in hydronephrosis was observed and there was no urinary complaint. In women presenting dilatation of upper urinary tract, pelvic organ prolapses must be kept in mind and a convenient examination is the key point to rule it out. Unnoticed cases can lead to a wrong diagnosis and redundant surgery. [ABSTRACT FROM AUTHOR]

A 69-year-old man who had undergone a transurethral resection of the prostate for benign prostatic hyperplasia developed necrosis of the glans penis following traction of the urethral catheter. [ABSTRACT FROM AUTHOR]