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People with high self-criticism tend to suffer from poor mental health whereas those with high self-reassurance tend to have good mental health. Poor mental health is a great cause for concern in Japan. Many people in Japan live with mental health issues, and the suicide rate is high. In particular, the mental health of caring professionals in Japan is devastated. However, there is no established measure to assess the levels of self-criticism and self-reassurance in the Japanese language. The Forms of Self-Criticising/Attacking & Self-Reassuring Scale (FSCRS) has been actively used in mental health research. Accordingly, this study aimed to develop the Japanese version of FSCRS (J-FSCRS). 300 nurses and 120 psychologists in Japan responded to an online survey containing J-FSCRS and Depression Anxiety Stress Scales-21. Confirmatory factor analyses and a Pearson's correlation analysis were conducted. J-FSCRS is proven to be reliable to assess self-criticism and self-reassurance in the Japanese language. [ABSTRACT FROM AUTHOR]

This study evaluated the efficacy of central nervous system (CNS) prophylaxis using intrathecal methotrexate (IT-MTX) in patients with diffuse large B-cell lymphoma (DLBCL). We retrospectively studied 322 patients who achieved first complete remission (CR) after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) therapy. The CNS prophylaxis consisted of four doses of IT-MTX (15 mg) with hydrocortisone (25 mg) administered after CR was achieved. Forty patients (12%) received CNS prophylaxis (group A) and 282 patients (88%) did not (group B). Three patients in group A (8%) and eight in group B (3%) experienced isolated CNS relapse during the first CR, although this difference was not statistically significant ( p = 0.14). Ten of 11 CNS relapses occurred in the brain parenchyma with ( n = 3) or without ( n = 7) leptomeningeal involvement, and the remaining patient had exclusive leptomeningeal involvement. In patients with DLBCL attaining CR after R-CHOP, IT-MTX administration was insufficient to prevent CNS relapse. [ABSTRACT FROM AUTHOR]

The article presents an analysis of the dissemination pattern in 184 cases of newly diagnosed mucosa-associated lymphoid tissue (MALT) lymphoma. The patients underwent a full staging, briefly consisting of physical examination, hematological and biochemical tests, chest radiography and biopsy before the initiation of therapy. The study found out the occurrence of multiorgan involvement more frequently in patients with primary extragastric lymphoma.