1. A new triterpenoid saponin from Ardisia gigantifolia.
- Author
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Mu, Li-Hua, Huang, Xiao-Wu, Guo, Dai-Hong, Dong, Xian-Zhe, and Liu, Ping
- Subjects
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ANALYSIS of variance , *APOPTOSIS , *BIOLOGICAL assay , *GLYCOSIDES , *HIGH performance liquid chromatography , *MOLECULAR structure , *RESEARCH funding , *STATISTICS , *PLANT extracts , *DATA analysis , *CYTOTOXINS , *DESCRIPTIVE statistics - Abstract
A new triterpenoid saponin, named 3-O-β-d-glucopyranosyl-(1 → 3)-β-d-xylopyranosyl-(1 → 2)-[α-l-rhamnopyranosyl-(1 → 3)]-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranosyl-3β,16α,28,30-tetrahydroxy-olean-12-ene (1), along with four known triterpenoids (2–5), was isolated from the rhizomes ofArdisia gigantifolia. Their structures were elucidated by spectroscopic methods. Compounds1–4showed cytotoxic activity against Hela, EJ, BCG, and HepG-2 cell lines. The percentage of early apoptotic cells after treatment with1was significantly increased compared with control cells (p < 0.05). [ABSTRACT FROM PUBLISHER]
- Published
- 2013
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