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Purpose: Little is known about the outcomes that are most important to prosthesis users and funders. A Prosthetic Interventions Core Outcome Set (PI-COS) will help researchers and practitioners measure outcomes that are the most important to prosthesis users and funders. Materials and methods: Prosthesis users and funders rated the importance of 121 International Classification of Functioning, Disability, and Health (ICF) second-level categories using a two-round Delphi survey. A Consensus Meeting using the nominal group technique resolved rating differences between groups. The ICF second-level categories were ranked according to importance and a K-Means Cluster Analysis helped establish the PI-COS. Results: 65 users and 8 funders completed the Delphi surveys, followed by a Consensus Meeting. 26 ICF second-level categories were considered important to prosthesis users and funders and a PI-COS of 14 ICF second-level categories drawn predominantly from five ICF chapters was established: Sensory Functions and Pain (b2), Neuromusculoskeletal and Movement-related Functions (b7), General Tasks and Demands (d2), Mobility (d4), and Products and Technology (e1). Conclusions: The PI-COS describes the outcomes that are most important to prosthesis users and funders. The PI-COS can help focus on the most important outcome measures in clinical practice and research, including future prosthetic health economic evaluations. [ABSTRACT FROM AUTHOR]

Purpose: After stroke, upper limb somatosensation can be impaired which affects motor control. Vision is often used to compensate for this. A clinical assessment which assesses the combined sensorimotor function in the absence of vision would be beneficial in studies targeting sensorimotor improvement. Methods and materials: We adapted the Action Research Arm Test (ARAT) to be performed without vision and called this modified version the sensorimotor ARAT (sARAT). Sixty healthy participants and 22 participants with chronic stroke performed the ARAT, sARAT, Fugl-Meyer upper extremity assessment (FM-UE) and Erasmus modified Nottingham sensory assessment (EmNSA). Discriminative validity of sARAT was evaluated by comparing performance between healthy participants and participants with chronic stroke. Convergent validity was evaluated by correlating sARAT with FM-UE and EmNSA. Results: Participants with stroke performed worse on the sARAT compared to healthy participants (p < 0.001), with median scores of 52 (IQR 32-57) and 57 (IQR 57-57), respectively. The sARAT showed high correlations with FM-UE and EmNSA (r = 0.80-0.90). Conclusions: The sARAT shows good discriminative and convergent validity in people with chronic stroke. It allows a quick assessment of the combined upper limb sensorimotor function, by performing the well-known ARAT with the eyes closed. IMPLICATIONS FOR REHABILITATION: The sensorimotor adaptation of the Action Research Arm Test (sARAT) is a clinical assessment of upper limb activity which is performed with the eyes closed. Combining the gold standard ARAT with the sensorimotor adaptation sARAT can inform about the influence of somatosensory impairments on upper limb activity in stroke survivors when vision is blocked. The sARAT shows good discriminative and convergent validity in persons with chronic stroke. [ABSTRACT FROM AUTHOR]

The role of tweety homolog 3 (TTYH3) has been studied in several cancers, including hepatocellular carcinoma, cholangiocarcinoma, and gastric cancer. The results showed that TTYH3 is highly expression in cervical cancer tissues and cells and high TTYH3 expression correlates with poor prognosis in patients with cervical cancer. TTYH3 markedly reduced the apoptosis rate and promoted proliferation, migration, and invasion. Silencing of TTYH3 has been shown to have an inhibitory effect on cervical cancer progression. Moreover, TTYH3 enhanced EMT and activated Wnt/β-catenin signaling. Furthermore, TTYH3 knockdown inhibited the tumor growth in vivo. In conclusion, TTYH3 promoted cervical cancer progression by activating the Wnt/β-catenin signaling. HIGHLIGHTS: TTYH3 is upregulated in cervical cancer tissue and cells. TTYH3 promotes cervical cancer cell proliferation. TTYH3 inhibits cervical cancer cell apoptosis. TTYH3 induces cervical cancer cell migration and invasion. TTYH3 activates the Wnt signaling in cervical cancer cell. [ABSTRACT FROM AUTHOR]

Objectives: To develop and validate a novel questionnaire aimed at providing a structured, evidence-based methodology for hearing aid recommendation and selection using self-reported importance ratings for different modern hearing aid features. Design: The initial questionnaire items were created through a concept mapping approach that involved input from hearing aid users. Hearing care professional focus groups (n = 10) were conducted to assess questionnaire content and design, and to guide modifications. Validation of this initial 34-item version of the questionnaire was conducted using an anonymous online survey tool (Qualtrics). Exploratory factor analysis was used to assess the factor structure of the dataset, using principal axis factoring. Questionnaire reliability and inter-item correlation were assessed. Items with low factor loading and high cross-loading were removed. Study sample: Two hundred and eighteen adult participants with a self-reported hearing loss (median age = 48 years, range = 18–95 years) completed the questionnaire. Results: Analysis and item removal resulted in a 28-item questionnaire. Three factors were identified, dividing the hearing aid features into the subscales: "Advanced connectivity & streaming", "Physical attributes & usability", and "Sound quality & intelligibility". Conclusion: This study has resulted in a patient-oriented questionnaire that allows clinicians to gather patient input in a structured manner. [ABSTRACT FROM AUTHOR]

The purpose of this study was to clarify the relationship between the efficiency of mechanical energy flow in the torso and bat head speed at impact. Ninety-eight amateur baseball players batted a light ball tossed from the pitcher direction 3.2 m away. The batting motion and ground reaction forces acting on each foot were recorded using a motion capture system and two force plates, respectively. The mechanical powers of the joint forces and joint torques were calculated to measure the generation, absorption, and transfer of mechanical energy in the torso. The transfer efficiency of mechanical energy in the torso was defined as the ratio of the mechanical energy inflow into the thorax from the torso joint to the mechanical energy outflow from the pelvis to the torso joint. The correlation coefficient between the bat head speed and transfer efficiency of mechanical energy in the torso was very low. Conversely, the mechanical energy flow in the torso was significantly correlated to the bat head speed. Therefore, the results suggest that the torso in baseball batting is not utilised for the generation of mechanical energy but acts as a pathway for the transfer of mechanical energy. [ABSTRACT FROM AUTHOR]

Online vendors often deploy limited-time and limited-quantity cues on their e-commerce sites to influence consumers purchase decisions. Although these scarcity cues can reflect genuine restrictions in the availability of goods, they are increasingly considered as ill-intentioned nudges or 'dark patterns' due to their omnipresence and success in persuading consumers. In an online experiment (N = 202), we examined the effects of limited-time and limited-quantity cues on perceived task load, perceived benevolence, and user experience. Results suggest that participants associated scarcity cues with a lack of benevolence from online vendors. E-commerce site design without scarcity cues provided participants with a superior hedonic and pragmatic user experience. In the case of limited-time scarcity cues, participants reported frustration-related negative emotions. We discuss the implications of these findings from the perspectives of dark pattern researchers, designers, and online vendors. [ABSTRACT FROM AUTHOR]

This study was designed to test the effects of two message features (source and level of autonomy support) that are commonly found in short-form social media (e.g. TikTok) videos about Pap tests. The source is defined as who is communicating the message, and autonomy support refers to providing an individual with the independence, respect, and choice to make their own decision. In an online experiment, 636 females aged 21–29 viewed TikTok videos about Pap tests varying in source (doctor vs. peer) and level of autonomy support (either using controlling language to demand getting a Pap test or being supportive of one's choice of whether they receive a Pap test) and then responded to outcomes measures including perceived source credibility, perceived message effectiveness, attitude toward the message, attitude toward Pap tests, intention to engage with the videos, and intention to get a Pap test. Doctors were perceived as more credible than peers, and doctor videos were perceived to be more effective than peer videos. Autonomy support interacted with source, such that autonomy-supportive videos delivered by a doctor improved attitude toward the messaging and attitude toward Pap tests. Regardless of the source, autonomy-supportive videos increased intention to engage with the content on social media. As Pap test rates have recently declined among young women in the United States and viewing of Pap test-related videos has skyrocketed on the TikTok platform, short-form social media sites like TikTok may be an effective health communication tool for health professionals. [ABSTRACT FROM AUTHOR]

Antibiotic resistance (AR) rates in Vietnam are among the highest in Asia, and recent infections due to multi-drug resistance in the country have caused thousands of deaths each year. This study investigated a Vietnamese community's preferences for antibiotic treatment and its knowledge and attitudes regarding antibiotics. A discrete choice experiment-based survey was developed and administered to the population of interest. The respondents were given sociodemographic-, knowledge- and attitude-related items and 17 pairs of choice tasks. Two hypothetical options were included in each choice task. Latent class analysis was conducted to determine the differences among the respondents' preferences. Among 1,014 respondents, 805 (79.4%) gave valid questionnaires. A three-latent-class model with four covariates (age, healthcare-related education or career, occupation, and attitude classifications) was used in the analysis. All five attributes significantly influenced the respondents' decisions. The majority, including young employed respondents with non-healthcare-related work or education, found treatment failure more important. Older respondents who had healthcare-related education/careers and/or appropriate antibiotic use- and antibiotics resistance-related attitudes, regarded contribution to antibiotic resistance as an important attribute in selecting antibiotic treatments. Unemployed individuals with correct knowledge identified the cost of antibiotic treatment as the most essential decision-making factor. Findings suggest minimal antibiotic impact on resistance; only 7.83% view it as amajor concern. The respondents exhibited substantial preference heterogeneity, and the general Vietnamese public had poor knowledge of and attitudes toward antibiotic use and antibiotic resistance. This study emphasizes the need for individual responsibility for antibiotic resistance and appropriate antibiotic use. [ABSTRACT FROM AUTHOR]

Objective: Couples' joint coping is important in managing the impact of breast cancer. However, measures assessing couples' communication as a way of coping are insufficient. This study aimed to generate a self-report valid and reliable measure of couples' coping with a particular focus on communication. Method: We used baseline data of 343 couple dyads who participated in a randomized clinical trial targeting marital communication. Women were diagnosed with early-stage breast cancer in the past eight months; couples were married or in an intimate relationship for at least six months, could read and write English, and lived within 100 miles of the study center. An expert panel selected items with conceptual fit from the Mutuality and Interpersonal Sensitivity Scale (MIS) that was originally designed to evaluate marital communication about breast cancer. Results: Exploratory and confirmatory factor analyses supported a 12-item measurement model with four factors: Keeping the communication open with each other about breast cancer (4 items), Sharing a positive outlook on breast cancer (2 items), Avoiding discussion of negative thoughts and feelings about breast cancer (3 items), and Spending sufficient time together talking about breast cancer (3 items). Reliability ranged from 0.76 to 0.87 for women and 0.70 to 0.83 for spouses. Conclusion: This new measure has potential application in clinical practice and future research to assess couple's joint coping efforts especially through communication. [ABSTRACT FROM AUTHOR]

In this study, we developed and validated the Clinical Student Version of the Japanese Interprofessional Competency Self-Assessment Scale (C-JASSIC) for healthcare students in their clinical practice phase. Data obtained from 331 students (medical, 98; nursing, 99; pharmacy, 134) during orientation for interprofessional education (pre-IPE) and from 319 students (medical, 94; nursing, 93; pharmacy, 132) within a week following IPE (post-IPE) were analyzed. Exploratory pre-IPE and Confirmatory post-IPE factor analyses revealed a consistent 6-factor structure aligning with the Japanese Interprofessional Competency domains. The scale exhibited strong internal consistency, with Cronbach's α values exceeding 0.8 for all factors both pre- and post-IPE. Scores for overall competency and individual domains increased post-IPE in 234 matched cases. A notable significant pre vs post difference concerned "Understanding of Others," indicating enhanced interprofessional comprehension after clinical practice. There was a weak but significant positive correlation between IPE satisfaction and difference in pre- and post-IPE scores. However, no significant differences were observed among medical, nursing, and pharmacy students. Despite its strengths, such as its competency-based design and cultural relevance to Japan, a limitation of the study may be potential self-reporting bias. Nonetheless, C-JASSIC represents a valuable tool for seamless competency evaluations from student to professional stages, with implications for broader Asian contexts. [ABSTRACT FROM AUTHOR]

To investigate the effect of dual-task training on balance and knee proprioception in both weight-bearing and non-weight-bearing conditions in older adults with significant imbalance and high risk of falling. This pre-posttest experimental design included 83 older adults (43 males, 40 females), selected based on age criteria (65–75 years) and specific inclusion and exclusion criteria. Participants underwent dual-task training consisting of 30-minute sessions, three times per week, for four weeks (totaling 12-sessions). Measures included Berg Balance Scale and knee proprioception deficit before and after dual-task training. The study showed statistically significant effect of dual-task training on balance (p < 0.001) and knee proprioception in both weight-bearing (p < 0.001) and non-weight-bearing (p < 0.001) in older adults. Pre-and post-measurements of independent variables between male and female older adults showed no significant difference. Dual-task training improves balance and knee proprioception in both weight-bearing and non-weight-bearing conditions in older individuals, thereby enhancing stability and reducing the risk of falls. [ABSTRACT FROM AUTHOR]

Background: Advance care planning (ACP) allows patients to define their goals and preferences. Spending more time at home and less time in the hospital, along with avoiding death in the hospital, are often considered desirable outcomes of palliative care (PC). In 2015, 36% of cancer patients died in the hospital and 13% died at home in Norway. Method: From 2015 to 2022, this prospective controlled non-randomized intervention trial observed 144 cancer patients with or without an organized ACP conversation in primary health care and a summarizing palliative plan (ClinicalTrials.gov Identifier: NCT02170168, 23 June 2014). The patients were identified through contact with the local cancer outpatient clinic or hospital-based PC team. Results: A total of 128 patients died during the observation period. Of these, 67 patients had an organized ACP conversation and summarizing palliative plan (intervention (I) group) and 61 had not (control (C) group). Dying in the hospital was significantly less common for patients in the I group compared to the C group (17.9% vs. 34.4%; X2 (1, n = 128) = 4.55, p = 0.033). There were no differences between the groups in terms of where they spent their time in the last 90 days of life (home, nursing home, or hospital). Most patients (62%) preferred to die at home. The observed differences between the groups regarding preferred and actual places of death did not reach statistical significance. Conclusion: With organized ACP conversations in primary health care and a summarizing palliative plan, cancer patients died less often in the hospital in our observational study. A structured ACP approach integrating palliative care for cancer patients into primary health care can support patients´ preferences at the end of life. [ABSTRACT FROM AUTHOR]

Background: Health literacy research in school gardening is lacking. Development of a psychometrically sound survey can fill this gap. Purpose: The purpose of this study was twofold: 1) to develop and validate a Functional Health Literacy Survey for School Gardening (FHLS-SG), and 2) to determine the effect of health literacy on reciprocal determinism between the individual, environmental, and behavioral factors of school gardening. Methods: 651 children in grades K-4 took the FHLS-SG with 31 questions about gardening and health literacy aligned to social cognitive theory. Results: Cronbach's alpha for 6 factors ranging from 0.69 to 0.84, and test-retest reliability ranging from 0.59 to 0.81 were statistically significant. Health literacy showed a small mediation effect (M) between vegetable eating behavior and the individual (M = 0.27) and vegetable eating behavior and the garden environment (M = 0.22). Health literacy had the strongest mediation effect (M = 0.36) between the garden environment and the individual. Discussion: When classroom environment was used as a covariate, health literacy mediated all relationships between the individual, environmental, and behavioral factors with small to medium effects (p <.01). Translation to Health Education Practice: Reciprocal determinism between individual, behavioral, and environmental factors was supported. Health literacy mediated all relationships with small to medium effects. The FHLS-SG can assess the mediating effect of health literacy on vegetable eating behavior within school garden environments. [ABSTRACT FROM AUTHOR]

Emergency medical services (EMS) clinicians are tasked with early fluid resuscitation for patients with sepsis. Traditional methods for prehospital fluid delivery are limited in speed and ease-of-use. We conducted a comparative effectiveness study of a novel rapid infusion device for prehospital fluid delivery in suspected sepsis patients. This pre-post observational study evaluated a hand-operated, rapid infusion device in a single large EMS system from July 2021-July 2022. Prior to device deployment, EMS clinicians completed didactic and simulation-based device training. Data were extracted from the EMS electronic health record. Eligible patients included adults with suspected sepsis treated by EMS with intravenous fluids. The primary outcome was the proportion of patients receiving goal fluid volume (at least 500 mL) prior to hospital arrival. Secondary outcomes included in-hospital mortality, disposition, and length of stay. Multivariable logistic regression was used to compare outcomes between 6-month pre- and post-implementation periods (July-December 2021 and February-July 2022, respectively), adjusting for patient demographics, abnormal prehospital vital signs, and EMS transport interval. Of 1,180 eligible patients (552 in the pre-implementation period; 628 in the post-implementation period), the mean age was 72 years old, 45% were female, and 25% were minority race-ethnicity. Median (interquartile range) fluid volume (in mL) increased between the pre- and post-implementation periods (600 [400,1,000] and 850 [500–1,000], respectively). Goal fluid volume was achieved in 70% of pre-implementation patients and 82% of post-implementation patients. In adjusted analysis, post-implementation patients were significantly more likely to receive goal fluid volume than pre-implementation patients (adjusted odds ratio (aOR) 2.00, 95% confidence interval (CI) 1.51–2.66). Pre-post in-hospital mortality was not significantly different (aOR 0.91, 95% CI 0.59–1.39). In a single EMS system, sepsis education and introduction of a rapid infusion device was associated with achieving goal fluid volume for suspected sepsis. Further research is needed to assess the clinical effectiveness of infusion device implementation to improve sepsis patient outcomes. [ABSTRACT FROM AUTHOR]

Exoskeleton robots are a promising solution to reduce musculoskeletal disorders (MSDs) in different work environments, but a specific usability scale for evaluating them is lacking. This study aimed to develop and verify a preliminary Exoskeleton Usability Questionnaire (EUQ) for the lower limb exoskeletons by creating a draft survey questionnaire from existing questions in prior studies. An experiment was conducted with 20 participants who performed a specific task while wearing three lower limb robots and provided subjective feedback using the developed questionnaire. Data were analysed using exploratory and confirmatory factor analysis (CFA), resulting in a usability evaluation questionnaire for exoskeleton robots clustered into four main factors: mobility, adjustability, handling and safety. This study's findings are expected to be useful in evaluating the usability of the lower limb exoskeletons in both general production sites and agricultural work, which can aid in reducing the prevalence of lower limb MSDs. Practitioner Summary: This study developed a preliminary subjective usability evaluation questionnaire for exoskeleton robots. The questionnaire is clustered into four main factors: mobility, adjustability, handling and safety. These findings provide a valuable tool for assessing exoskeleton usability, potentially reducing musculoskeletal disorders (MSDs) in various work environments. [ABSTRACT FROM AUTHOR]

Objectives. The COVID-19 pandemic, remote work and new technologies have heightened workplace pressures. Effective response and essential organizational changes require business leaders to be more adaptable, with managers' presence playing a pivotal role in successful implementation. The study assesses a brief mindfulness-based emotional regulation for managers (MBERM) intervention, to reduce workplace stress and enhance managerial well-being. Methods. An 8-week non-randomized controlled trial was conducted with a waiting list control group and an intervention group. Pre–post differences were measured by Student's t test or Wilcoxon test, and effect size calculated using the Hedge's g formula. The sample included 23 managers (17 men and six women) with average age 50 years. The study assessed anxiety and depressive symptoms, psychological flexibility, perceived self-efficacy, general work-related well-being, perceived stress and mindfulness. Results. Statistically significant changes were observed in the intervention group in depression, anxiety, work-related acceptance and action, general self-efficacy, exhaustion, alienation, stress and non-reactivity. The control group showed no statistically significant changes in any of the variables. Conclusion. The MBERM intervention could improve the emotional and work-related well-being of managers and reduce stress levels and burnout. Further study of this intervention is needed to promote adherence and ensure a long-term improvement. [ABSTRACT FROM AUTHOR]

The present study investigated the transversal rotation of body and its relation to the horizontal movement for expert shooters and novices in a pistol aiming task. Participants stood on a force plate with an air pistol and aimed it to the centre of a target, positioned 1.4 m above the floor and 10 m away from the force plate, for 30 s as accurately as possible. The results revealed that the novice group showed greater transversal body variability represented by the free moment (FM) than the expert group. Correlation analysis showed that there is tight coupling between the FM and centre of pressure both in the anterior–posterior and medio-lateral directions for the expert group while only strong coupling of that in the anterior–posterior direction for the novice group. The findings suggest that FM is a critical factor to accurately aim the pistol on the target and there is a different postural strategy, in terms of the body motion in the transversal and horizontal space, as a function of skill level to realise success in the pistol aiming task. [ABSTRACT FROM AUTHOR]

Health communication scholars have provided ample evidence demonstrating the ways in which freedom-threatening language used in persuasive health messages evokes freedom-threat perceptions, state psychological reactance, and intentions to engage in behaviors opposite of those recommended by the health message. This study examined a novel mitigation strategy for diminishing these outcomes. We examined whether prior exposure to entertainment portrayals of moral virtue (versus a neutral video) can dampen audiences' psychological reactance, intentions to consume alcohol, and defensive message processing via their psychophysiological responses to a subsequent, freedom-threatening excessive alcohol consumption public service announcement (PSA). The results revealed that participants who viewed entertainment portrayals of moral virtue (N = 50 college-aged participants) self-reported higher levels of elevation, moved, and inspiration relative to participants in the control condition (N = 50 college-aged participants). Participants who were exposed to entertainment portrayals of moral virtue prior to the excessive alcohol consumption PSA also self-reported less psychological reactance and fewer behavioral intentions to consume alcohol following the excessive alcohol consumption PSA than participants in the control condition. Consistent with these self-report data, participants in the entertainment portrayals of moral virtue condition exhibited less defensive message processing of the excessive alcohol consumption PSA via their psychophysiological responses relative to the control group. The results indicate that initial exposure to entertainment portrayals of moral virtue can dampen audiences' cognitive, emotional, and behavioral responses to a subsequent, freedom-threatening health message, thereby increasing the chances of improved health outcomes. [ABSTRACT FROM AUTHOR]

The lack of daily conversation may lead to the deterioration of quality of life and cognitive function in older adults requiring long-term care. This study aimed to develop a scale to measure daily conversation among them, the Life-Worldly Communication Scale: LWCS, and to test its structural, convergent, and discriminant validity. The subjects were 539 older adults requiring long-term care in facilities and at home. A 24-item provisional scale was created, using a panel of experts. Structural validity of LWCS was examined from exploratory factor analysis to establish the factor structure, two confirmatory factor analyses for cross-validation, and measurement invariance between the institutional and home setting. Convergent validity was examined from the average variance extracted: AVE, composite reliability: CR, and simple regression analysis between LWCS and Interdependent Happiness Scale: IHS. Discriminant validity was examined using the heterotrait-monotrait ratio of correlations: HTMT. Multiple imputations were used to deal with missing data on these scales. The results showed that the goodness of fit of the three-factor, 11-item model obtained from the two-step CFA was SRMR =.043, RMSEA =.059, CFI =.978, and AGFI =.905. The model was confirmed for structural validity by measurement invariance tests: configural invariance (CFI=.973, RMSEA =.047), metric invariance (ΔCFI=.001, ΔRMSEA=−.004), scalar invariance (ΔCFI =-0.002, RMSEA = −0.003). Convergent validity was confirmed by AVE =.503~.772, CR =.801~.910, and simple regression analysis between LWCS and IHS (adjusted r2=.18, p <.001). Discriminant validity was also confirmed among the three factors (HTMT=.496~.644). LWCS can contribute to the assessment of daily conversation in geriatric settings and research regarding its promotion. [ABSTRACT FROM AUTHOR]

This paper explicates blame as a psychological construct in communication processes, with a focus on its underlying structure and its mediating role between message characteristics and the public's issue engagement. Data were collected from Amazon Mechanical Turk (N = 373) via a Web-based experiment, where we manipulated a news story about a child suffering an obesity-related health risk (asthma attack vs. heart attack) with different levels of preventability (high vs. low) and severity (high vs. low). Findings showed that blame should best be conceptualized and operationalized as a latent construct comprising both cognitive and affective components. Blame mediated message effects on social responses related to obesity prevention, including punitive attitudes, policy support, and intentions toward interpersonal communication and civic participatory behaviors. [ABSTRACT FROM AUTHOR]

Hyperlipidemia is a risk factor for stroke, and worsens neurological outcome after stroke. Endothelial progenitor cells (EPCs), which become dysfunctional in cerebral ischemia, hold capacity to promote revascularization. We investigated the role of dyslipidemia in impairment of EPC-mediated angiogenesis in cerebral ischemic mice. The high fat diet (HFD)-fed mice following by ischemic stroke exhibited increased infarct volumes and neurological severity scores, and poorer angiogenesis. Bone marrow-EPCs treated with palmitic acid (PA) showed impaired functions and inhibited activity of AMP-activated protein kinase (AMPK). Notably, AMPK deficiency aggravated EPC dysfunction, further decreased mitochondrial membrane potential, and increased reactive oxygen species level in EPCs with PA treatment. Furthermore, the expression of fatty acid oxidation (FAO)-related genes was remarkably reduced, and carnitine palmitoyltransferase 1A (CPT1A) protein expression was downregulated in AMPK-deficient EPCs. AMPK deficiency aggravated neurological severity scores and angiogenesis in ischemic brain of HFD-fed mice, accompanied by suppressed protein level of CPT1A. EPC transplantation corrected impaired neurological severity scores and angiogenesis in AMPK-deficient mice. Our findings suggest that AMPK deficiency aggravates poor angiogenesis in ischemic brain by mediating FAO and oxidative stress thereby inducing EPC dysfunction in hyperlipidemic mice. [ABSTRACT FROM AUTHOR]

Although almost every study evaluating psychological interventions includes the two components of acceptability and effectivity, their relationship is rarely examined. The current study closes this gap by performing secondary analyses of the intervention program 'empCARE'. The goal was to analyze the relationship between these two evaluation components. The sample consists of 309 nurses (intervention group n = 172; control group n = 137). Data were collected before the training and longitudinally three times after the training. Psychological distress was assessed using the Symptom Checklist (SCL-90-R), and the Copenhagen Burnout Inventory. Personality traits were assessed using the HEXACO-60 and the Toronto Empathy Questionnaire. Acceptability was assessed using statements concerning participants' subjective evaluation of the training. The results show that the intervention program was effective. Acceptability, measured only in the intervention group, was quite high. However, no connection was found between effectivity and acceptability. On the contrary, the results show that acceptability assessments depend more on personality factors than on intervention success. Researchers should examine the relationship between acceptability and effectivity in their data. It does not seem appropriate to rely on acceptability measurements as the sole evaluation criterion capturing the success of an intervention. [ABSTRACT FROM AUTHOR]

The self-reference effect (SRE) is a memory advantage produced by encoding information in a self-relevant manner. The "evaluative" SRE arises when people engage in explicit self-evaluation/reflection to process to-be-remembered items, while the "incidental" SRE occurs when self-referential information (e.g., one's own name) is co-presented with to-be-remembered items but is irrelevant to a given task. Using a divided-attention paradigm, the present study examined potential differences in the attentional requirements of the evaluative and incidental SREs. During encoding, personality-trait words were presented simultaneously with the participant's own or a celebrity's name. The participants' task was either to evaluate whether each word described themselves/the celebrity (evaluative encoding) or to indicate the location of each word (incidental encoding), in the presence or absence of a secondary task. A subsequent recognition test with a remember/know procedure showed better overall recognition and enhanced episodic recollection for words presented with one's own name vs. another name, with this SRE being larger in the evaluative than incidental encoding condition. Critically, divided attention at encoding attenuated the magnitudes of both evaluative and incidental SREs to a comparable degree in overall recognition and episodic recollection. These findings suggest that both the evaluative and incidental SREs are resource-demanding, effortful mnemonic benefits. [ABSTRACT FROM AUTHOR]

This study investigates the effects of information presentation on operator performance in digital control systems at different levels of task difficulty in order to resolve the conflict between 'large amounts of information' and 'limited display'. By using software to present figures of varying difficulty as target information, the operator's behaviour such as page switching and target clicking is simulated to obtain data. Simultaneously, eye-tracking technique was used to analyse how the way information was presented at different levels of difficulty influenced the subjects' search performance. The results show that subjects' performance gradually decreases as the difficulty of the numbers grows for both presentations, and it is found that the complexity of the content of the navigation bar may have influenced the subjects to some extent. In addition, the different position of the navigation bar where the target is located will result in a change in the search pattern. It is noticeable that dividing the single page into double pages can effectively alleviate the contradiction of 'large amount of information' and 'limited display' in designing the system interface. Therefore, this study provides certain guideline value for the interface design of digital control systems. [ABSTRACT FROM AUTHOR]

Conversational technologies such as chatbots have shown to be promising in eliciting self-disclosure in several contexts. Implementing such a technology that fosters self-disclosure can help to assess sensitive topics such as behaviours that are perceived as unaccepted by others, i.e. the exposure to unaccepted (alternative) news sources. This study tests whether a conversational (chatbot) format, compared to a traditional web-based survey, can enhance self-disclosure in the political news context by implementing a two-week longitudinal, experimental research design (n = 193). Results show that users disclose unaccepted news exposure significantly more often to a chatbot, compared to a traditional web-based survey, providing evidence for a chatbots' ability to foster the disclosure of sensitive behaviours. Unlike our hypotheses, our study also shows that social presence, intimacy, and enjoyment cannot explain self-disclosure in this context, and that self-disclosure generally decreases over time. [ABSTRACT FROM AUTHOR]

Voice assistants (VAs), such as Alexa, Siri, or Google Now, are becoming increasingly ubiquitous. Consequently, the potential societal impacts of such systems are gaining relevance in public and academic discourses. Investigating the effects of VA voice features on user perception of VAs is one central aspect of research. Here, the potential effects of VAs on the perception of gender roles and the attribution of gender stereotypes stand out. Following the Computers as Social Actors paradigm, it is assumed that gendered voices have the potential to reproduce existing gender stereotypes. Yet, recently, the implementation of gender-ambiguous voices has been suggested to mitigate such effects and promote more diverse technology design. In this study, we set out to inquire about the relationship between gendered VA voice (male, female, gender-ambiguous) and gender stereotype activation. In two online surveys with an experimental manipulation (Study 1: N = 140, Study 2: N = 397), we test stereotype activation as a function of VA voice, user gender, and conversation topic. Empirical findings are mixed, with no effects for conversation topic but indications of small effects of VA voice. Implications for future research are discussed. [ABSTRACT FROM AUTHOR]

Contingency management (CM) is an evidence-based behavioral intervention highly effective at promoting behavior change. Despite evidence of its efficacy, the extension of CM to the treatment of harmful gambling has been slow. Wider dissemination of CM may be facilitated through identification of perceived obstacles and barriers. The present study developed items for a new scale, the Contingency Management for Gambling Provider Survey (ConGam-PS), to measure the views of gambling treatment providers of CM for gambling. In a mixed methods (qualitative and quantitative) based approach, N = 111 UK gambling treatment providers were surveyed about their positive, negative, and neutral beliefs about CM. Descriptive analyses found that participants were open to using and receiving training in CM, and supported research on CM for treatment of gambling. Common concerns involved the potential negative consequences for clients when incentives are withdrawn and the feasibility of objectively verifying gambling abstinence. No significant associations were found between participant characteristics and CM beliefs. Overall, there is openness toward CM among treatment providers and further research and evaluation of CM for harmful gambling is warranted. [ABSTRACT FROM AUTHOR]

This study investigates the impact of Body Mass Index (BMI) on Quality of Life (QoL) and treatment outcomes in breast cancer (BC) patients, particularly focusing on underweight individuals with compromised nutritional status. A nonrandomized prospective study comprising 121 newly diagnosed patients across various BMI categories utilized FACT-B & FACIT-Sp-12 questionnaires. Follow-ups occurred at baseline, during (3rd and 6th), and after (12th month) anthracycline-taxane chemotherapy, either sequentially or concomitantly. Patients with low BMI (<18.5 kg/m2; 53.7%) exhibited significantly poorer QoL, marked by compromised nutritional indicators (low MUAC and SFT). Repeated measures ANOVA identified significant correlations between BMI groups in functional, social, and emotional QoL aspects (p < 0.05), with no notable differences in other domains. A Chi-square (ꭓ2) test underscored a significant link between BMI and treatment response (p < 0.0001), showing higher rates of non-responders among underweight patients (p = 4.259e−14). The study advocates pretreatment consultation with a dietitian as standard care for Indian BC patients, offering complimentary nutritional support for improved QoL outcomes and treatment responses. [ABSTRACT FROM AUTHOR]

To investigate the usability and effectiveness of standardized circuit class group training (CCT) compared to individualized goal-directed group training (GDT) in subacute stroke survivors. This study consists of three parts. Part 1 involved a pragmatic, non-randomized controlled trial with subacute participants and their therapists, who participated in four weeks either CCT or GDT. Superiority of the intervention was defined as significantly larger improvement on the Motor Activity Log for patients and lower workload for therapists. In Part 2, six additional workstations were developed for CCT. Part 3 replicated the study of Part 1 with the expanded CCT. Part 1 showed no difference in effectiveness between training methods. CCT did not match the rehabilitation goals of the patient sufficiently, however mental workload seemed lower for therapists. An expansion of CCT could improve the match between the patient's goals and the training (Part 2). Results of Part 3 showed again no difference in effectiveness between methods. CCT was however perceived as less engaging compared to GDT, but mental load for therapists remained lower. A standardized training could reduce the mental workload for therapists, but patients seemed less engaged. A combination of both might be most beneficial.Trial registration: Dutch Trial Register: NL8844 and NL9471 Providing a standardized training program after stroke reduces therapists' mental workload. Individualized goal-directed group training results in the best achievement of rehabilitation goals. A combination of standardized and individual training would use best of both intervention modalities. Patients should be involved in the co-creation developing process of training programs. [ABSTRACT FROM AUTHOR]

Despite the prevalence and negative outcomes associated with simultaneous alcohol and cannabis use (i.e., marijuana [SAM] use, i.e., so that the effects of both alcohol and cannabis overlap) among college students, there is no comprehensive measure of SAM use, with past research relying on single items. The present study aimed to develop the Alcohol and Cannabis Simultaneous Use Scale (ACSUS), a comprehensive self-report measure of SAM use frequency, quantity, and problems in college students. College students at two Midwestern universities who used alcohol and cannabis (Study 1: N = 534; Mean age = 19; 71% female; 88% White; Study 2: N = 258; Mean age = 21; 81% female; 85% White) completed the newly developed ACSUS. Exploratory factor analysis (Study 1) revealed that the ACSUS fits best with 9-items representing two factors: Factor 1 measures frequency and quantity of SAM use and Factor 2 measures associated problems with SAM use. Confirmatory factor analysis (Study 2) supported the two-factor structure of the ACSUS, which was positively associated with measures of alcohol use, cannabis use, simultaneous use motives, and impulsivity. These data provide initial support for the ACSUS, developed to investigate the frequency, quantity, and associated problems with SAM use in college students. [ABSTRACT FROM AUTHOR]

Working memory tasks, such as n-back and arithmetic tasks, are frequently used in studying mental workload. The present study investigated and compared the sensitivity of several physiological measures at three levels of difficulty of n-back and arithmetic tasks. The results showed significant differences in fixation duration and pupil diameter among three task difficulty levels for both n-back and arithmetic tasks. Pupil diameters increase with increasing mental workload, whereas fixation duration decreases. Blink duration and heart rate (HR) were significantly increased as task difficulty increased in the n-back task, while root mean square of successive differences (RMSSD) and standard deviation of R-R intervals (SDNN) were significantly decreased in the arithmetic task. On the other hand, blink rate and Galvanic Skin Response (GSR) were not sensitive enough to assess the differences in task difficulty for both tasks. All significant physiological measures yielded significant differences between low and high task difficulty except for SDNN. Practitioner summary: This study aimed to assess the sensitivity levels of several physiological measures of mental workload in n-back and arithmetic tasks. It showed that pupil diameter was the most sensitive in both tasks. This study also found that most physiological indices are sensitive to an extreme change in task difficulty levels. [ABSTRACT FROM AUTHOR]

To assess if a high-level mobility programme (HLMP) can promote sustained participation in physical activity by adolescents with cerebral palsy. Eight adolescents with cerebral palsy, Gross Motor Function Classification System levels I-II, 11–16 years, participated in 24 community-based group HLMP sessions across 12 weeks. Participants set attendance, involvement, and physical performance goals, completed activity diaries over 58 weeks and undertook physical capacity tests. Measures of activity frequency and diversity (attendance) and involvement level were collected weekly across baseline (4–6 weeks), intervention (12 weeks), and nine months follow-up (including Covid lockdown). Median attendance was 23 of 24 HLMP sessions. Attendance goal/s attainment was highest during COVID lockdown. Involvement goals were consistently attained throughout all phases. Physical performance goal/s attainment was highest during intervention phase but reduced during nine months follow-up. Frequency of participation in physical activities varied greatly across study phases (range 0–33 episodes/week) with stable variety of activities and generally high 'involvement.' During the intervention, seven participants improved physical capacity and six maintained, or increased, the gains six months later. Most participants improved physical capacity post-intervention but only some had sustained attendance and involvement in physical activity, highlighting the complexity of physical activity participation. Health professionals' promotion of sustained participation in physical activity needs to consider individual preferences for frequency, diversity and duration. Supporting and measuring involvement in physical activity should be prioritised as a key outcome of an intervention. Physical activity interventions should be followed up for longer than six months to determine sustained changes in participation outcomes Measuring physical capacity and performance gains alone is insufficient to determine sustained, meaningful participation. [ABSTRACT FROM AUTHOR]

Aim: The present study was planned with the aim of developing a scale for measuring individuals' online health information-seeking behavior. Material and Method: The study was carried out between 9.12.2022 and 14.01.2023 with individuals aged 18 and over who were residing in Yalova, Türkiye. The study sample included 395 participants. Results: Exploratory factor analysis showed that the developed scale comprised one dimension and five items. Confirmatory factor analysis was subsequently utilized to verify the structure of the scale, and the goodness-of-fit results supported the scale's construct validity. Furthermore, the reliability coefficient of the scale was high. According to these findings, the newly developed Conclusion: Online Health Information-Seeking Behavior Scale is both valid and reliable, and it can be administered in evaluating individuals' online health information-seeking behaviors. [ABSTRACT FROM AUTHOR]

This study aims to develop a Portuguese-language version of the Birth Satisfaction Scale-Revised (BSS-R) for clinical and research use in Portugal (PT-BSS-R). The factor structure, its invariance across depression levels, and the internal consistency of the PT-BSS-R were analysed. A sample of 1373 Portuguese-speaking postpartum women completed a sociodemographic and clinical form, the PT-BSS-R, and the Edinburgh Postnatal Depression Scale through an online survey tool. Four competing models were tested through confirmatory factor analyses and bifactor model-based psychometric indices were calculated. The internal consistency and the divergent/convergent validity are analysed. The psychometric properties of PT-BSS-R were found to be generally excellent. Both the original correlated three-factor model and the bifactor model exhibited a good fit to the data. Results from the bifactor model support the use of both the BSS-R total score and the subscale scores. Exemplary invariance findings were observed between groups stratified on the basis of depression screening. PT-BSS-R has demonstrated both divergent and convergent validity as well as internal consistency. PT-BSS-R is a psychometrically robust measure of birth satisfaction appropriate for clinical and research use in Portugal. [ABSTRACT FROM AUTHOR]

Following a traumatic brain injury (TBI), people frequently have difficulty understanding nonliteral language, including irony and indirect requests. Despite the handicap that these disorders can represent in daily life, they are rarely treated clinically, and remediation studies are scarce. The present study thus aimed to evaluate the effectiveness of an explicit metapragmatic therapy targeting nonliteral language comprehension and taking into account cognitive processes likely to underlie this comprehension (i.e., contextual processing, theory of mind, and executive functions). This study was registered on the ClinicalTrials.gov system (ID: NCT04708561) before participant recruitment. Two adults with severe TBI took part in the study. An ABA design with multiple baselines was used to assess the evolution of treated and non-treated written literal and nonliteral story comprehension, as well as ecological tasks and tasks assessing the cognitive processes of interest (theory of mind and executive functions). An interview was also conducted at the end of treatment to assess participant satisfaction. Therapy resulted in significant improvement in treated items, with one-month maintenance of gains and generalisation to untreated items in both participants. The generalisation to a working memory task was also observed in one participant. Finally, participant satisfaction with the treatment was high. Our study demonstrated for the first time the potential of a therapy targeting irony and indirect request comprehension in TBI individuals. Clinically, it offers concrete therapeutic avenues and fills a critical gap in the TBI population's evidence for the remediation of nonliteral language comprehension. [ABSTRACT FROM AUTHOR]

Sexual assault is prevalent among undergraduates in Greek-letter organizations (GLO). Prevention efforts promote sexual consent, though few explicitly employ theoretical constructs known to positively influence behavior. This study evaluated theory-informed educational posters promoting sexual consent seeking. Forty undergraduate GLO students (20 female, 20 male) were recruited through in-person, email, and social media solicitation. Data collection was completed March–November 2019 during the spring and fall semesters. A double-blind randomized controlled trial was conducted. Intervention participants viewed theory-informed educational posters promoting sexual consent. The intervention group demonstrated more favorable consent intention (p =.024; η2 = 0.131) and consent subjective norms (p =.040; η2 = 0.109). Intervention group males showed a greater improvement in one of four consent attitudes (p =.045; η2 = 0.211). Brief exposures to theory-informed messaging may help to improve subjective norms and behavioral intent to seek sexual consent among undergraduate GLO members. [ABSTRACT FROM AUTHOR]

The goal of this study was to adopt the concept of climate, which has been researched extensively in the context of organizational psychology, to the study of communities and develop a scale for community climate of involvement. We demonstrate that communities can constitute a valid level of analysis for the study of climate. The scale development was done in two steps: Step 1, a qualitative investigation of 39 geographical community members, found evidence of the existence of climate in communities and identified a climate facet that is relevant to the study of communities – involvement. Based on the qualitative data collected in this step, we then developed a community involvement climate scale. Step 2 tested the reliability and homogeneity of the community involvement climate in a sample of 300 participants from six communities. The results of the study attest to the existence of climate in communities and provide a valid and reliable community involvement climate scale. We discuss the contributions of this study and suggest future studies on climate in communities. [ABSTRACT FROM AUTHOR]

This pilot study sought to determine the feasibility of quantifying sensory processing, postural control, motor skill development and participation in daily life in children with idiopathic toe walking (ITW) compared to children without ITW. A nonrandomized, prospective case-control design was employed. Twenty participants were recruited. Computerized weight bearing and postural control data was successfully collected. Differences were found in forefoot/rearfoot weight bearing, balance, sensory-motor abilities and parent reported participation challenges. Sensory processing results were inconclusive. Findings can inform standardized assessment and treatment of ITW. [ABSTRACT FROM AUTHOR]

This study was conducted to develop a measurement tool to achieve ketogenic diet management in parents of children with epilepsy and examine its Turkish psychometric properties. The study was conducted on 317 parents using a descriptive correlational method. Data analysis and evaluation were performed using factor analysis, Cronbach's alpha, and item – total score correlation. The scale consists of 20 items and unidimensional factor. As a result of the exploratory factor analysis, the total explained variance of the unidimensional factor was 63.809%. Cronbach's alpha coefficient of the scale was 0.971. The four-weeks test-retest reliability evaluated with intra-class correlation was 0.87. Confirmatory factor analysis indicated, the model fit index results were recorded as follows: 0.95 as the Goodness-of-Fit Index; comparative fit index, 0.96 and normed fit index, 0.94. The study determined that the Ketogenic Diet Management Scale for Children with Epilepsy-Parent Form is a measurement tool that can be used by health professionals and that is used to evaluate parents' ketogenic diet knowledge. [ABSTRACT FROM AUTHOR]

The aim of this pilot study was to explore the feasibility and language outcomes of coaching parents to implement an aided language stimulation intervention using Pragmatic Organisation Dynamic Display (PODD) communication books. Two parent–child dyads, with children aged 4 years 6 months and 4 years 8 months participated in a home-based intervention. An AB design was used. Data were collected in mealtime and play activities. Dependent variables were frequency of parent use of AAC symbols and speech and frequency of child symbol use (speech, signs or graphic symbols). The intervention was feasible as parents reported they were confident in implementing it and the timeframes were appropriate for single-case research designs. An increase in parent AAC symbol use was associated with PODD book use in mealtime and for one parent in play. Both children increased their symbol use, with the clearest association in the mealtime activity. Overall, the encouraging results suggest that this approach warrants further research using stronger designs. [ABSTRACT FROM AUTHOR]

Despite increasing demands, the uptake of parenting education programs in developing countries is limited. This study evaluated the effectiveness of a Learning Through Play (LTP) informed, illustration-based parent educational training program designed for low-literacy populations in Bangladesh to promote early childhood development. A quasi-experimental design was employed, involving parents of typically developing children and children with special needs aged 0–6 years. Results showed significant enhancements in parenting knowledge, skills, and attitudes in both groups, with larger effects on knowledge and attitudes among parents of special needs children. The findings underscore the potential of LTP Calendar-based educational training programs as cost-effective, culturally sensitive, and accessible strategies for enhancing positive parenting practices and child development outcomes in economically disadvantaged settings. Future research should focus on cultural sensitivity evaluation, sample size expansion, and long-term impact assessment to further validate and extend these findings. [ABSTRACT FROM AUTHOR]

Are semantic impairments in Alzheimer's disease (AD) partially due to deficits in spatial attention? In a target detection task, both older adults (OAs) and AD individuals were facilitated by valid spatial cues, but only OAs were impaired by invalid cues compared to neutral. In a reading task, spatial cues validly or invalidly cued the location of pictures, which were related or unrelated to subsequent, centrally presented, words. OAs showed semantic priming only after valid cues, whereas AD individuals showed priming after valid and invalid cues. Failure to inhibit uncued locations results in processing of potentially distracting semantic information in AD. [ABSTRACT FROM AUTHOR]

We evaluated the psychometric properties of the Trauma Informed Practice Scales – School Counseling Programs Version scores using item response theory with a sample of 270 school counselors. Participants ranged in age from 24 to 69 years (M = 42.82, SD = 9.96). Participants identified as female (81.5%), male (14.1%) or unreported (4.4%,). Participants' racial and ethnic backgrounds were: White (79.3%), African American or Black (5.6%), Multiracial (5.2%), Latino/Hispanic/Spanish (4.8%), American Indian/Alaskan Native (0.4%), Other (0.4%), or unreported (4.4%). Participants from 14 states completed an online survey, which included demographics questions and the TIPS-SCP. After removing the poorly performing items, partial credit model estimates explained 58.63% of the variance in participant responses. We found psychometric evidence to support its ability to capture trauma informed practices in schools and school counseling programs. The TIPS-SCP is a brief instrument to provide school counselors with a self-assessment of their trauma informed practices. The TIPS-SCP can aid school counselors in making data-informed decisions about immediate and future incorporations of integrating trauma informed practices into their schools and school counseling programs. [ABSTRACT FROM AUTHOR]

Mental health conditions are a significant global health concern. To address this concern, sport settings are increasingly being viewed as environments in which to support individual mental health and wellbeing. Not all sports settings are, however, conducive to supporting mental health. Efforts to improve mental health in sport settings are likely to be less effective if the club culture, policy, and environment do not promote behaviors known to support mental health. Understanding the extent to which sport clubs offer environments conducive to mental health and wellbeing is important for mental health initiatives targeting sport clubs. Currently and to our knowledge, there is no known instrument that captures member/participant perceptions of how supportive the sport setting is regarding mental health and wellbeing. This study explored the content validity, internal construct validity and external construct validity of the Supporting Mental Health in Sport Instrument (SMHSI) intended to measure the extent to which sport clubs provided a supportive environment for mental health promotion. A process of reliability analysis, principal component analysis and Rasch analysis was conducted confirming the psychometric fit of the items to the overall construct. The instrument could distinguish between two sport club environments providing different levels of mental health support, demonstrating external construct validity. The instrument can be used to evaluate the effectiveness of the sport club context to support mental health, to identify suitable club targets for mental health programs, to better determine training needs, or to better understand the impact of mental health programs on wider club contexts. Lay summary: Mental health promotion in sport clubs is becoming increasingly popular. The effectiveness of these promotion efforts may be compromised by the contexts in which they are delivered. This paper describes the properties of the Supporting Mental Health in Sport Instrument designed to measure the contextual support for the promotion of mental health in sport clubs. This instrument can be used by sport organizations and researchers to measure the extent to which sport club environments are supportive of the mental wellbeing of members and identify suitable targets for mental health programs. Mental health organizations looking to use sport club settings to deliver mental health interventions can use the instrument to tailor their mental health programs and resources as well as better understand the context in which their intervention is being delivered. Organizations and researchers looking to promote mental health in sport club settings can use the instrument to determine the impact of programs on the wider sporting context. Organizations and researchers can direct scarce funding and resources toward supporting sport clubs that demonstrate greatest need in relation to improving their culture and environment to better support mental health. [ABSTRACT FROM AUTHOR]

While the role of autobiographical memory in self-representation is well established, the identity function of future thinking has received much less attention. Yet, most people commonly imagine future events that convey meaningful information about the person they wish or expect to become. In three experiments, we assessed the extent to which thinking about such self-defining future events influences the current content of self-representation (i.e., the working self-concept). Participants were asked to think about either a past or future self-defining event, or a control topic, before describing aspects of their identity in the form of "I am" statements (Experiments 1 and 3) or completing scales assessing self-related dimensions (Experiments 2 and 3). We found that thinking about a future self-defining event led participants to conceptualise themselves more in terms of their psychological traits, as did thinking about a past self-defining event. Furthermore, thinking about a future self-defining event increased the sense of present-future self-continuity, whereas thinking about a past self-defining event increased the sense of past-present self-continuity. These results suggest that self-representations are fuelled not only by autobiographical memories, but also by projections into the future. [ABSTRACT FROM AUTHOR]

This paper is aiming to present two studies investigating attitudes of older people towards different technologies to break their social isolation and investigating the impacts of Immersive Virtual Reality (IVR) on physical and mental dimensions. The first study, based on focus groups conducted with 23 older people (aged from 65 to 93 years-old) allowed to collect attitudes and opinions of older people about different technologies to help them to break social isolation. The second study, based on an experiment conducted with 42 older people (aged from 63 to 85 years-old) allowed to investigate the impact of a specific Immersive Virtual Reality (IVR) on physical and mental dimensions. The first study confirm that Immersive Virtual Reality (IVR) can be a relevant digital tool for elderly people according to them, i.e. a digital tool perceived as useful, usable and acceptable. The second study demonstrates that use of a specific Immersive Virtual Reality (IVR) system can reduce the perception of social isolation and can have positive impacts on physical dimensions such as the weight and the waist circumference. Theoretical and applied implications are discussed. [ABSTRACT FROM AUTHOR]

In a go/no-go task, lengthening the inter-trial interval (ITI) or decreasing the press percentage (PP) are known to have decelerating effects on both reaction time and on thought probe response time. The mental causes of these delays remain obscure. We performed an 18-minute online experiment with 60 participants who each performed 8 versions of an attention task (Test of Variables of Attention, ToVA) with different ITIs and PPs. After each block there were mind wandering (MW) thought probes and rating scales for subjective effort and awareness. A version of the ToVA with zero no-go-stimuli spontaneously and implicitly accelerated mean reaction time significantly. That version also quickened three subsequent response times for rating tasks by hundreds of milliseconds, which suggests that the basis of this effect is a lingering mental state. None of the subjective ratings measured were strongly related to the reaction time delay, although MW seems to delay the thought probe response. We conclude that there may be another lingering state besides MW. To perform different tasks participants make mental speed-accuracy trade-offs whereby the participant adopts a lingering mental strategy that speeds up thinking by reducing caution/uncertainty, quickening both reaction times and thought probe response times. [ABSTRACT FROM AUTHOR]

Problematic gaming may lead to poor mental health and negative social outcomes. Existing harm minimisation strategies predominately focus on school-based education, government legislation, and player protection programmes of the video gaming industry. From the perspective of players, the present research explored and evaluated beliefs and behaviours adopted by players to protect themselves from gaming-related harms. In Study 1, potential protective beliefs and behaviours were identified from focus group interviews among players. A survey was conducted to explore the factor structure of the protective beliefs and behaviours scale (PBBS). Based on parallel analysis, we found three belief factors and two behaviour factors that were negatively related to problematic gaming. In Study 2, the psychometric properties of PBBS were tested. Its factor structure was replicated in the confirmatory factor analysis, and the composite reliability and average variance extracted revealed adequate construct validity. The predictive validity of PBBS was demonstrated by its negative associations with problematic gaming symptoms and impulsiveness, as well as positive associations with self-control, self-esteem, and well-being. These protective beliefs and behaviours seemed to be promising in reducing gaming-related harms. The PBBS would be useful for evaluating players' vulnerability to problematic gaming and providing insights into player-centred prevention strategies. [ABSTRACT FROM AUTHOR]

This study was conducted to evaluate the effects of hypno-breastfeeding (HB) and solution-focused psychoeducation (SFP) on breastfeeding motivation and insufficient milk perception in mothers. It is a randomized controlled experimental study. The sample of the study consisted of 90 women who met the inclusion criteria. Women in the intervention groups had increased motivation to breastfeed and decreased perception of insufficient milk. Those in the SFP group had significantly lower midwife support scores than the HB group. HB and SFP are safe and effective methods to increase mothers' motivation to breastfeed and reduce the perception of insufficient milk. [ABSTRACT FROM AUTHOR]

A new triterpenoid saponin (1), along with five known compounds (2–6), was isolated from Bupleurum marginatum Wall. ex DC, of which compounds 2–4 were obtained for the first time from this plant. The structures were confirmed by the analysis of 1D, 2D NMR, and HR-ESIMS data, and comparison with previous spectral data. Anti-liver fibrotic activities of the isolates were determined as proliferation inhibition of LPS-induced activation of HSC-T6 in vitro. [ABSTRACT FROM AUTHOR]