1. Mastoiditis complicated with Gradenigo syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus.
- Author
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Bravo D, Machová H, Hahn A, Marková H, Otruba L, Mandys V, Houstava L, and Kalvach P
- Subjects
- Anti-Bacterial Agents therapeutic use, Ceftriaxone therapeutic use, Cerebrospinal Fluid immunology, Drug Therapy, Combination, Humans, Hypertrophy pathology, Immunoglobulin G cerebrospinal fluid, Immunosuppressive Agents therapeutic use, Magnetic Resonance Imaging, Male, Mastoiditis drug therapy, Mastoiditis pathology, Meninges pathology, Meningitis pathology, Methotrexate therapeutic use, Methylprednisolone therapeutic use, Middle Aged, Otitis Media surgery, Syndrome, Abducens Nerve Diseases complications, Chloramphenicol therapeutic use, Hydrocephalus complications, Hydrocephalus pathology, Mastoiditis complications, Meningitis complications, Meningitis drug therapy, Otitis Media complications, Petrous Bone pathology, Trigeminal Nerve Diseases complications
- Abstract
We present the clinical, radiological and pathological features of a case of a cranial hypertrophic pachymeningitis that developed in the course of mastoiditis and petrous apex inflammation and responded to immunosuppressive therapy only. Documented by the development of clinical findings, magnetic resonance imaging, cerebrospinal fluid changes, histopathology findings, by otosurgical intervention and finally by the insertion of a ventriculo-peritoneal shunt, the case illustrates a gradual development of pachymeningitis with consequent hydrocephalus and intracranial hypertension. We consider this disease development an example of immune-induced proliferative fibrotic changes in meninges.
- Published
- 2007
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