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Your search keyword '"Fandamu, Paul"' showing total 2 results
Start Over Author "Fandamu, Paul" Publisher taylor & francis
2 results on '"Fandamu, Paul"'

1. Hepatitis E virus infection in pigs: a first report from Zambia

Author

Chambaro, Herman M., Sasaki, Michihito, Muleya, Walter, Kajihara, Masahiro, Shawa, Misheck, Mwape, Kabemba E., Harima, Hayato, Qiu, Yongjin, Hall, William W., Fandamu, Paul, Squarre, David, Simulundu, Edgar, Sawa, Hirofumi, and Orba, Yasuko

Subjects
viruses, virus diseases, digestive system diseases
Abstract

While evidence suggests presence of HEV infection in humans in Zambia, currently, there is no information on its occurrence in domestic pigs. Here, we investigated the presence of HEV antibodies and genome in domestic pigs in Zambia. Sera (n = 484) from domestic pigs were screened for antibodies against HEV by ELISA while genome detection in fecal (n = 25) and liver (n = 100) samples from slaughter pigs was conducted using nested RT–PCR assay. Overall, seroprevalence was 47.7% (231/484) while zoonotic genotype 3 HEV RNA was detected in 16.0% (20/125) of slaughtered pigs. This is the first report to highlight occurrence of HEV infection in domestic pigs in Zambia. This finding suggests possible contamination of the pork supply chain. Moreover, there is a potential risk of zoonotic transmission of HEV to abattoir workers, pig farmers and handlers.

Published
2021
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2. Hepatitis E virus infection in pigs: a first report from Zambia.

Author

Chambaro HM, Sasaki M, Muleya W, Kajihara M, Shawa M, Mwape KE, Harima H, Qiu Y, Hall WW, Fandamu P, Squarre D, Simulundu E, Sawa H, and Orba Y

Subjects
Abattoirs, Animals, Hepatitis Antibodies blood, Hepatitis E blood, Hepatitis E epidemiology, Hepatitis E virology, Hepatitis E virus genetics, Hepatitis E virus isolation & purification, Seroepidemiologic Studies, Sus scrofa blood, Sus scrofa virology, Swine, Swine Diseases blood, Swine Diseases epidemiology, Zambia epidemiology, Hepatitis E veterinary, Hepatitis E virus immunology, Swine Diseases virology
Abstract

While evidence suggests presence of HEV infection in humans in Zambia, currently, there is no information on its occurrence in domestic pigs. Here, we investigated the presence of HEV antibodies and genome in domestic pigs in Zambia. Sera ( n  = 484) from domestic pigs were screened for antibodies against HEV by ELISA while genome detection in fecal ( n  = 25) and liver ( n  = 100) samples from slaughter pigs was conducted using nested RT-PCR assay. Overall, seroprevalence was 47.7% (231/484) while zoonotic genotype 3 HEV RNA was detected in 16.0% (20/125) of slaughtered pigs. This is the first report to highlight occurrence of HEV infection in domestic pigs in Zambia. This finding suggests possible contamination of the pork supply chain. Moreover, there is a potential risk of zoonotic transmission of HEV to abattoir workers, pig farmers and handlers.

Published
2021
Full Text
View/download PDF

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