1. Autoimmunity-associated autonomic failure with sympathetic denervation.
- Author
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Goldstein DS, Holmes C, Sullivan P, Donadio V, Isonaka R, Zhong E, Pourier B, Vernino S, Kopin IJ, and Sharabi Y
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Valsalva Maneuver physiology, Autoimmunity physiology, Pure Autonomic Failure diagnostic imaging, Pure Autonomic Failure immunology, Sympathectomy
- Abstract
We report a case of autoimmunity-associated autonomic failure in a young adult woman who developed arthritis followed 3 years later by pandysautonomia. There was early recovery of parasympathetic functions but persistent neurogenic orthostatic hypotension from post-ganglionic sympathetic denervation. Clinical laboratory testing indicated variable amounts of sympathetic neuronal re-sprouting in the heart, kidneys, eyes, and body as a whole upon follow-up evaluation after 1.5 years.
- Published
- 2017
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