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1. Molecular characterization of chikungunya virus from the first cluster of patients during the 2020 outbreak in Chad.

Author

Yonga MG, Yandai FH, Sadeuh-Mba S, Abdallah AH, Ouapi D, Gamougam K, Abanda NN, Endengue-Zanga MC, Demanou M, and Njouom R

Subjects
Chad epidemiology, Disease Outbreaks, Genotype, Humans, Phylogeny, Chikungunya Fever epidemiology, Chikungunya virus genetics
Abstract

We sequenced a portion of the E1 envelope protein gene of two of four CHIKV RT-PCR-positive samples from the first cluster of chikungunya patients during the 2020 Chad outbreak. Phylogenetic analysis revealed that the viruses belonged to the East/Central/South/African genotype but lacked the E1 A226V and K211E mutations associated with viral adaptability and transmission, suggesting an autochthonous transmission. These sequences are a useful basis for tracking viral evolution in subsequent outbreaks in Chad., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)

Published
2022
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