32 results on '"Mandrup-Poulsen T"'
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2. Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children
3. Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
4. Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
5. IL-1β-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
6. Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection
7. Proliferation of sorted human and rat beta cells
8. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells
9. IL-1β-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line
10. Growth arrest- and DNA-damage-inducible 45β gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1β-induced apoptosis in insulin-producing INS-1E cells
11. Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action
12. Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor κB-mediated gene expression in insulin-producing INS-1E cells
13. Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
14. An immune origin of type 2 diabetes?
15. Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes
16. Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1β-mediated toxicity through inhibition of multiple nuclear factor-κB-regulated proapoptotic pathways
17. IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis
18. Complete mutation scan of the human Fas ligand gene: Linkage studies in Type I diabetes mellitus families
19. A choice of death – the signal-transduction of immune-mediated beta-cell apoptosis
20. TNFα and IFNγ potentiate IL-1β induced mitogen activated protein kinase activity in rat pancreatic islets of Langerhans
21. Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with Type I diabetes mellitus
22. The role of interleukin-1 in the pathogenesis of IDDM
23. Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats
24. Repetitive in vivo treatment with human recombinant interleukin-1β modifies Beta-cell function in normal rats
25. Assessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays
26. Functional and morphological effects of interleukin-1β on the perfused rat pancreas
27. An immune origin of type 2 diabetes?
28. What are the types and cellular sources of free radicals in the pathogenesis of Type 1 (insulin-dependent) diabetes mellitus?
29. Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans
30. Affinity-purified human Interleukin I is cytotoxic to isolated islets of Langerhans
31. Increased reduction in fasting C-peptide is associated with islet cell antibodies in Type 1 (insulin-dependent) diabetic patients
32. Insulin autoantibodies are associated with islet cell antibodies; their relation to insulin antibodies and B-cell function in diabetic children
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