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Your search keyword '"Hagmann, S."' showing total 29 results
Start Over Author "Hagmann, S." Publisher springer-verlag
29 results on '"Hagmann, S."'

2. Storage ring at HIE-ISOLDE: Technical design report

Author

Grieser, M., Litvinov, Yu. A., Raabe, R., Blaum, K., Blumenfeld, Y., Butler, P. A., Wenander, F., Woods, P. J., Aliotta, M., Andreyev, A., Artemyev, A., Atanasov, D., Aumann, T., Balabanski, D., Barzakh, A., Batist, L., Bernardes, A. -P., Bernhardt, D., Billowes, J., Bishop, S., Borge, M., Borzov, I., Bosch, F., Boston, A. J., Brandau, C., Catford, W., Catherall, R., Cederkäll, J., Cullen, D., Davinson, T., Dillmann, I., Dimopoulou, C., Dracoulis, G., Düllmann, Ch. E., Egelhof, P., Estrade, A., Fischer, D., Flanagan, K., Fraile, L., Fraser, M. A., Freeman, S. J., Geissel, H., Gerl, J., Greenlees, P., Grisenti, R. E., Habs, D., von Hahn, R., Hagmann, S., Hausmann, M., He, J. J., Heil, M., Huyse, M., Jenkins, D., Jokinen, A., Jonson, B., Joss, D. T., Kadi, Y., Kalantar-Nayestanaki, N., Kay, B. P., Kiselev, O., Kluge, H. -J., Kowalska, M., Kozhuharov, C., Kreim, S., Kröll, T., Kurcewicz, J., Labiche, M., Lemmon, R. C., Lestinsky, M., Lotay, G., Ma, X. W., Marta, M., Meng, J., Mücher, D., Mukha, I., Müller, A., Murphy, A. St J., Neyens, G., Nilsson, T., Nociforo, C., Nörtershäuser, W., Page, R. D., Pasini, M., Petridis, N., Pietralla, N., Pfützner, M., Podolyák, Z., Regan, P., Reed, M. W., Reifarth, R., Reiter, P., Repnow, R., Riisager, K., Rubio, B., Sanjari, M. S., Savin, D. W., Scheidenberger, C., Schippers, S., Schneider, D., Schuch, R., Schwalm, D., Schweikhard, L., Shubina, D., Siesling, E., Simon, H., Simpson, J., Smith, J., Sonnabend, K., Steck, M., Stora, T., Stöhlker, T., Sun, B., Surzhykov, A., Suzaki, F., Tarasov, O., Trotsenko, S., Tu, X. L., Van Duppen, P., Volpe, C., Voulot, D., Walker, P. M., Wildner, E., Winckler, N., Winters, D. F. A., Wolf, A., Xu, H. S., Yakushev, A., Yamaguchi, T., Yuan, Y. J., Zhang, Y. H., and Zuber, K.

Published
2012
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6. The enhancement effect in K-shell radiative recombination of $\mbox{\sffamily\bfseries U}^{\hbox{\sffamily\bfseries\fontsize{10}{12}\selectfont 92+}}$ ions with cooling electrons

Author

Banaś, D., Pajek, M., Stöhlker, Th., Beyer, H. F., Böhm, S., Bosch, F., Brandau, C., Czarnota, M., Chatterjee, S., Dousse, J.-Cl., Fritzsche, S., Gumberidze, A., Hagmann, S., Kozhuharov, C., Kumar, A., Liesen, D., Mokler, P. H., Müller, A., Reuschl, R., Schmidt, E. W., Sierpowski, D., Spillmann, U., Surzhykov, A., Szlachetko, J., Tashenov, S., Trotsenko, S., Verma, P., and Warczak, A.

Published
2009
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26. [Hip joint contractures, leg length discrepancies, and spinopelvic alignment: impact on the development of osteoarthritis of the hip?]

Author

Götze M and Hagmann S

Subjects
Acetabulum, Adolescent, Adult, Child, Hip Joint, Humans, Leg, Osteoarthritis, Hip surgery, Contracture, Osteoarthritis, Hip diagnostic imaging
Abstract

Hip joint problems are common in every-day orthopedic practice. At the age of 60, approximately 5% of the German population suffer from symptomatic osteoarthritis of the hip. One of the main trigger is the morphological abnormality of the joint. Causes may also be overloading of the joint, developmental dysplasia of the hip with reduced coverage, as well as femoral or acetabular malpositioning, for example. The impact of hip joint contractures, leg length discrepancies, and the spinopelvic alignment and their prophylactic treatment in childhood, adolescence and early adulthood are discussed here.

Published
2020
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27. [Torticollis in children].

Author

Götze M and Hagmann S

Subjects
Algorithms, Child, Diagnosis, Differential, Humans, Incidence, Infant, Newborn, Muscular Diseases, Torticollis
Abstract

Background: Torticollis is a common neck deformity in both newborn and older children. The various causes of the abnormal posturing of the head differ in severity, long-term consequences and their treatment., Methods: This article gives an overview of the differential diagnoses of torticollis in children and current literature, and provides insight into our diagnostic and therapeutic algorithm., Results: A distinction is drawn between congenital and acquired deformities and whether or not they are painful. Most commonly, children present with a congenital muscular torticollis, which has an estimated incidence of 0.3 to 1.9%. The main differential diagnosis of congenital muscular torticollis is Klippel-Feil syndrome. Acquired torticollis often has more severe causes and always needs a thorough diagnostic clarification., Conclusion: The knowledge of possible causes and their treatment is essential to provide adequate care for affected children and their families and to prevent long-term consequences.

Published
2019
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28. Xenogeneic transplantation of articular chondrocytes into full-thickness articular cartilage defects in minipigs: fate of cells and the role of macrophages.

Author

Niemietz T, Zass G, Hagmann S, Diederichs S, Gotterbarm T, and Richter W

Subjects
Animals, Bone Remodeling, Cell Differentiation, Cell Survival, Chondrocytes cytology, Collagen Type II genetics, Collagen Type II metabolism, Female, Humans, Hypoxanthine Phosphoribosyltransferase metabolism, Mice, SCID, RNA, Messenger genetics, RNA, Messenger metabolism, Regeneration, Species Specificity, Swine, Swine, Miniature, Cartilage, Articular pathology, Chondrocytes transplantation, Macrophages metabolism, Transplantation, Heterologous
Abstract

Xenogeneic or allogeneic chondrocytes hold great potential to build up new cartilage in vivo. However, immune rejection is a major concern for the utility of universal donor-derived cells. In order to verify the reported immune privilege of chondrocytes in vivo, the aim of this study was to assess engraftment of human articular chondrocytes (HAC) in minipig knee cartilage defects and their contribution to cartilage regeneration. HAC were transplanted matrix-assisted within two hydrogels into full-thickness cartilage defects of minipigs or implanted ectopically into immune deficient mice to assess redifferentiation capacity. At 2 and 4 weeks after surgery, cell-persistence and host cell invasion were monitored by species-specific in situ hybridization and RT-PCR. Early tissue regeneration was evaluated by histomorphometry and a modified O'Driscoll score. HAC capable of successful in vivo chondrogenic redifferentiation persisted at ectopic sites for 4 weeks in both carrier materials. Early defect regeneration involved extensive host cell invasion and a decline of HAC to less than 5 % of initial cell numbers in 6/12 defects within 2 weeks. Few clusters of persisting HAC within collagen type II-rich tissue were surrounded by porcine macrophages. Four weeks after cell transplantation, most of the defects contained well-integrated cell-rich tissue free of human cells with no apparent difference between hydrogel carriers. In summary, HAC failed to engraft in porcine articular cartilage defects despite their ability for successful in vivo redifferentiation. The co-localization of macrophages to hydrogel-implanted HAC suggests active graft rejection without evidence for an immune-privileged status of xenogeneic chondrocytes in a large animal joint.

Published
2014
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29. [In vitro analysis of the impact of metal ions on human lymphocyte cultures].

Author

Hagmann S, Kirsch J, Kretzer JP, and Moradi B

Subjects
Aged, Apoptosis drug effects, Cell Survival drug effects, Cells, Cultured, Female, Humans, Ions pharmacology, Lymphocytes cytology, Male, Biocompatible Materials pharmacology, Lymphocytes drug effects, Lymphocytes physiology, Metals pharmacology
Abstract

The use of metal implants has become increasingly more frequent in all fields of medicine throughout the past decades. Numerous studies have demonstrated that metal ions released from these implants can be detected in body fluids remote from the implants. Although diseases directly linked to the release of these ions seem to be rare, the general public is unsettled. In this study we aimed to analyze the impact of molybdenum(V), cobalt(II), chromium(III) and nickel(II) ions on cell surface markers (CD25, CD38, CD69, CD95) and viability (7-AAD/AnnexinV) of human CD4+ T-lymphocytes in vitro. Cobalt(II) ions at a concentration of 1000 μg/l led to a significant suppression of lymphocyte activation markers while nickel(II), chromium(III) and molybdenum(V) did not show any significant impact on these lymphocyte activation markers. Cell viability was significantly reduced by all metal ions, whereas cobalt(II) led to the highest increase of apoptotic cells and was the only metal ion to significantly increase the necrosis rate. While the pathophysiological significance of these findings remains unclear, they are in favour of further research in this field.

Published
2013
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