3,079 results
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2. Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer
3. Assessment of the absorption, metabolism and excretion of [14C]pasireotide in healthy volunteers using accelerator mass spectrometry
4. Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers
5. Pharmacokinetics of colistin in critically ill patients with multidrug-resistant Gram-negative bacilli infection
6. Dopamine D2/3 occupancy of ziprasidone across a day: a within-subject PET study
7. Prenatal exposure to escitalopram and/or stress in rats: A prenatal stress model of maternal depression and its treatment
8. Update on 1-benzylpiperazine (BZP) party pills
9. Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats
10. Effects of ketoconazole and esomeprazole on the pharmacokinetics of pazopanib in patients with solid tumors
11. Phase I study of oral gemcitabine prodrug (LY2334737) in Japanese patients with advanced solid tumors
12. Pharmacokinetics, Tissue Distribution and Excretion of Recombinant Human Parathyroid Hormone 1–84 in Animals
13. Simultaneous Determination of α- and γ-Mangostins in Mouse Plasma by HPLC–MS/MS Method: Application to a Pharmacokinetic Study of Mangosteen Extract in Mouse
14. Hollow-Fiber-Based LPME as a Reliable Sampling Method for Gas-Chromatographic Determination of Pharmacokinetic Parameters of Valproic Acid in Rat Plasma
15. Pharmacokinetic disposition of anagliptin, a novel dipeptidyl peptidase-4 inhibitor, in rats and dogs
16. C max and t max verification using Fibonacci sequence and absorption rate
17. Bioavailability of intravenous fosphenytoin sodium in healthy Japanese volunteers
18. Correlation of contrast agent kinetics between iodinated contrast-enhanced spectral tomosynthesis and gadolinium-enhanced MRI of breast lesions
19. Influence of Bariatric Surgery on the Use and Pharmacokinetics of Some Major Drug Classes
20. Pharmacokinetics and tissue distribution of larotaxel in rats: comparison of larotaxel-loaded microsphere with larotaxel-solution
21. A phase I pharmacokinetic study of PM00104 (Zalypsis®) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors
22. Validated LC-ESI-MS/MS Method for the Quantitation of Neopanaxadiol: a Novel Neuroprotective Agent from Panax ginseng and Its Application to a Pharmacokinetic Study in Rat Plasma
23. Simultaneous Quantification of Aliskiren, Valsartan and Sitagliptin by LC with Fluorescence Detection: Evidence of Pharmacokinetic Interaction in Rats
24. Therapeutic drug monitoring for tomorrow
25. Pharmacokinetics of teduglutide in subjects with renal impairment
26. Pharmakokinetische Parameter: Altersbedingte Änderungen und Einfluss auf die Therapiefähigkeit
27. A phase I study of tasisulam sodium using an albumin-tailored dose in Japanese patients with advanced solid tumors
28. A mathematical model for the administration of temozolomide: comparative analysis of conventional and metronomic chemotherapy regimens
29. Pharmacokinetics Study of Amoxycillin and Clavulanic acid (8:1)-A New Combination in Healthy Chinese Adult Male Volunteers Using the LC–MS/MS Method
30. Medikamentöse Therapie bei Frauen – Was gilt es zu beachten?
31. CYP2C19 genotype has a major influence on labetalol pharmacokinetics in healthy male Chinese subjects
32. Effect of the P450 oxidoreductase *28 polymorphism on the pharmacokinetics of tacrolimus in Chinese healthy male volunteers
33. A phase I study to assess the effect of food on the single dose bioavailability of the THC/CBD oromucosal spray
34. Polymorphisms of UGT1A9 and UGT2B7 influence the pharmacokinetics of mycophenolic acid after a single oral dose in healthy Chinese volunteers
35. Effect of rifampicin on the pharmacokinetics and pharmacodynamics of ticagrelor in healthy subjects
36. Educational paper: Do we need neonatal clinical pharmacologists?
37. Correlations between the selected parameters of the chemical structure of drugs and between-subject variability in area under the curve
38. Evaluation of chemically diverse 5-HT2C receptor agonists on behaviours motivated by food and nicotine and on side effect profiles
39. Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine
40. A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors
41. Phase I dose-escalation study of oral vinflunine administered once daily for 6 weeks every 8 weeks in patients with advanced/metastatic solid tumours
42. Pharmacokinetics of docetaxel in gastric cancer patients with malignant ascites
43. Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years
44. Impaired bioavailability and antiplatelet effect of high-dose clopidogrel in patients after cardiopulmonary resuscitation (CPR)
45. Medication prescribing in frail older people
46. Pharmacokinetic and pharmacodynamic effects of comedication of clopidogrel and dabigatran etexilate in healthy male volunteers
47. The effect of genetic polymorphisms in UGT2B15 on the pharmacokinetic profile of sipoglitazar, a novel anti-diabetic agent
48. Single ascending oral dose pharmacokinetics and pharmacodynamics study of EV-077: the specific inhibitor of prostanoid- and isoprostane-induced cellular activation
49. Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers
50. Pharmacokinetics of cisplatin during hyperthermic intraperitoneal treatment of peritoneal carcinomatosis
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