29 results
Search Results
2. A euglycaemic/non-diabetic perinatal environment does not alleviate early beta cell maldevelopment and type 2 diabetes risk in the GK/Par rat model
3. Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice
4. Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance
5. Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis
6. Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans
7. Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat
8. Imaging the islet graft by positron emission tomography
9. Towards PET Imaging of Intact Pancreatic Beta Cell Mass: A Transgenic Strategy
10. Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat
11. Pancreatic alpha cell mass in European subjects with type 2 diabetes
12. Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation
13. The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
14. Bioluminescence Imaging in Mouse Models Quantifies β Cell Mass in the Pancreas and After Islet Transplantation
15. Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys
16. Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice
17. Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass
18. The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality
19. A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis
20. Early loss of mammalian target of rapamycin complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic nuclear factor 1-α (HNF1A) function in INS-1 insulinoma cells
21. Imaging the pancreas: from ex vivo to non-invasive technology
22. The enteroinsular axis may mediate the diabetogenic effects of TCF7L2 polymorphisms
23. Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto–Kakizaki rat model of type 2 diabetes
24. Adenoviral overproduction of interleukin-1 receptor antagonist increases beta cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome
25. Evidence for the homeostatic regulation of induced beta cell mass expansion
26. Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans
27. Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation
28. Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide–streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas
29. Metabolic adaptations to chronic glucose infusion in rats
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