1. Suprasellar germinoma in three lake whitefish (Coregonus clupeaformis).
- Author
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Mikaelian I, Lapointe JM, de Lafontaine Y, Harshbarger JC, Côté RJ, Naydan DK, and Martineau D
- Subjects
- Animals, Germinoma pathology, Sella Turcica, Skull Base Neoplasms pathology, Animal Diseases pathology, Brain pathology, Fishes, Germinoma veterinary, Skull Base Neoplasms veterinary
- Abstract
Suprasellar germinomas were identified in three wild-caught lake whitefish (Coregonus clupeaformis) from the St. Lawrence River, Quebec, Canada. Histologically, the three tumors expanded the subarachnoid space of the ventral surface of the brain immediately adjacent to the pituitary gland and, in one case, infiltrated the adjacent neuropil. These tumors were characterized by nests and sheets of round cells with a high mitotic rate, separated by a scant amount of loose fibrovascular stroma. The stroma was infiltrated by a moderate number of small mononuclear cells, including rare CD3-immunoreactive lymphocytes. This is the first report of intracranial germinoma in a fish species.
- Published
- 2000
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