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1. The 'Hemolysis Model' for the Study of Cyto-Toxicity and Cyto-Protection by Bile Salts and Phospholipids

Author

Marcin Krawczyk, Antonio Moschetta, Giuseppe Palasciano, Piero Portincasa, Michele Petruzzelli, Michele Vacca, Vincenzo Palmieri, and Francesco Minerva

Subjects
Bile acid, Biochemistry, medicine.drug_class, Toxicity, medicine, Human erythrocytes, Endogeny, Mixed micelle, medicine.disease, Hemolysis, In vitro model
Abstract

The hemolysis of human erythrocytes can be proposed as a valuable in vitro model to study the interaction of different molecules with the plasma membrane: given its simplicity and versatility, this method provides a reliable tool to screen potentially damaging or protective compounds like drugs, nutrients and endogenous molecules, with relevance to the pathophysiology and treatment of human diseases.

Published
2006
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