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2. Interrelations Between Phosphorus, Calcium, Parathyroid Hormone, and Phosphate Excretion in the Normal and Uremic Dog

Author

Michael A. Kaplan, Eric Reiss, Janet M. Canterbury, George Gavellas, and Neal S. Bricker

Subjects
medicine.medical_specialty, Phosphorus, chemistry.chemical_element, Parathyroid hormone, medicine.disease, Phosphate, Uremia, Excretion, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, Absorption (logic), Homeostasis, Hormone
Abstract

Phosphorus homeostasis is maintained in animals and man by excretion through the kidneys of the same amount of phosphorus absorbed from the intestines on an ongoing basis. There is apparently little impairment of gastrointestinal phosphorus absorption in uremia (1); yet phosphorus balance is well maintained in animals and man with advancing chronic renal disease. This balance is accomplished by progressive increases in fractional excretion of phosphate (\((F{{E}_{P{{O}_{4}}}})\)) by the kidneys and associated increases in para-thyroid hormone (PTH) secretion (2–5).

Published
1978

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