1. Structure and Regulated Expression of Bovine Prolactin and Bovine Growth Hormone Genes
- Author
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Yvonne Yao, Robert K. Hampson, Sally A. Camper, Dennis Sakai, Robert H. Lyons, Richard P. Woychik, Edward C. Goodwin, and Fritz M. Rottman
- Subjects
medicine.medical_specialty ,Biology ,Growth hormone ,Prolactin ,medicine.anatomical_structure ,Endocrinology ,Anterior pituitary ,Internal medicine ,Gene expression ,medicine ,Gene family ,Bovine somatotropin ,Gene ,Hormone - Abstract
Prolactin and growth hormone are members of a gene family which has been extensively studied during the past several years (Miller and Eberhardt, 1983). Along with the gonadotropins, the members of this gene family are primarily expressed in the anterior pituitary. The expression of these genes and their corresponding regulatory factors has been of interest from the perspective of differential regulation during developmental stages, hormonal effects on gene expression, and the possibility of expression at ectopic sites other than the pituitary (Gluckman et al., 1981). Studies described in this manuscript are restricted to the growth hormone and prolactin genes and more specifically to aspects of gene structure which influence the level of their respective mRNAs.
- Published
- 1986