Search

Your search keyword '"Circulating tumor cells"' showing total 134 results
Start Over Descriptor "Circulating tumor cells" Publisher springer us
134 results on '"Circulating tumor cells"'

33. Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Author

Mohamed Bentires-Alj, Elsa Charifou, Beatrice A. Howard, Alexandra Van Keymeulen, and Gunnhildur Asta Traustadottir

Subjects
Oncology, Cancer Research, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Branching, Mammary gland, Biology, Lineage tracing, Metastasis, Circulating tumor cell, Breast cancer, Internal medicine, medicine, Premetastatic niche, Transcriptomics, Breast development, Tumor microenvironment, Circulating tumor cells, Cancer, Tumor dormancy, medicine.disease, Signaling, Organoids, Patient-derived xenografts, In vivo live imaging, medicine.anatomical_structure, Editorial, Resistance to therapy
Abstract

The twelfth annual workshop of the European Network for Breast Development and Cancer focused on methods in mammary gland biology and breast cancer, was scheduled to take place on March 26–28, 2020, in Weggis, Switzerland. Due to the COVID-19 pandemic, the meeting was rescheduled twice and eventually happened as a virtual meeting on April 22 and 23, 2021. The main topics of the meeting were branching and development of the mammary gland, tumor microenvironment, circulating tumor cells, tumor dormancy and breast cancer metastasis. Novel and unpublished findings related to these topics were presented, with a particular focus on the methods used to obtain them. Virtual poster sessions were a success, with many constructive and fruitful interactions between researchers and covered many areas of mammary gland biology and breast cancer.

Published
2021

37. Application of single-cell sequencing technologies in pancreatic cancer

Author

Begum Dariya, Obul Reddy Bandapalli, and Mastan Mannarapu

Subjects
0301 basic medicine, Clinical Biochemistry, Cell, Disease, Computational biology, Biology, Genome, Article, Metastasis, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Circulating tumor cell, Pancreatic cancer, medicine, Humans, Molecular Biology, Circulating tumor cells, Cell Biology, General Medicine, medicine.disease, Pancreatic Neoplasms, 030104 developmental biology, medicine.anatomical_structure, Single cell sequencing, Single-cell sequencing, 030220 oncology & carcinogenesis, Intratumor heterogeneity, Single-Cell Analysis, Sequence Analysis
Abstract

Pancreatic cancer (PC) is the third lethal disease for cancer-related mortalities globally. This is mainly because of the aggressive nature and heterogeneity of the disease that is diagnosed only in their advanced stages. Thus, it is challenging for researchers and clinicians to study the molecular mechanism involved in the development of this aggressive disease. The single-cell sequencing technology enables researchers to study each and every individual cell in a single tumor. It can be used to detect genome, transcriptome, and multi-omics of single cells. The current single-cell sequencing technology is now becoming an important tool for the biological analysis of cells, to find evolutionary relationship between multiple cells and unmask the heterogeneity present in the tumor cells. Moreover, its sensitivity nature is found progressive enabling to detect rare cancer cells, circulating tumor cells, metastatic cells, and analyze the intratumor heterogeneity. Furthermore, these single-cell sequencing technologies also promoted personalized treatment strategies and next-generation sequencing to predict the disease. In this review, we have focused on the applications of single-cell sequencing technology in identifying cancer-associated cells like cancer-associated fibroblast via detecting circulating tumor cells. We also included advanced technologies involved in single-cell sequencing and their advantages. The future research indeed brings the single-cell sequencing into the clinical arena and thus could be beneficial for diagnosis and therapy of PC patients.

Published
2021

42. Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer

Author

Jauch, Sarah F., Riethdorf, Sabine, Sprick, Martin R., Schütz, Florian, Schönfisch, Birgitt, Brucker, Sara Y., Deutsch, Thomas M., Nees, Juliane, Saini, Massimo, Becker, Lisa M., Burwinkel, Barbara, Sinn, Peter, Marmé, Frederik, Pantel, Klaus, Jäger, Dirk, Sohn, Christof, Trumpp, Andreas, Wallwiener, Markus, and Schneeweiss, Andreas

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results