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2 results on '"C. Dechenne"'

1. Two Cases of Renal Interstitial Granulomatous Lesions with Improvable Renal Failure in Sarcoidosis

Author

C. Dechenne, G. Cornet, and D. Dive

Subjects
Pathology, medicine.medical_specialty, Membranous nephropathy, Methylprednisolone, business.industry, Interstitial nephritis, medicine, Sarcoidosis, Glomerular lesion, medicine.disease, business, Granulomatous lesions, medicine.drug
Abstract

Two cases of interstitial nephritis in sarcoidosis with improvable renal failure, using methylprednisolone, are described. The effectiveness of such a therapy is discussed.

Published
1991

2. Relation Between Urinary Proteinases and Proteinuria in Rats with a Glomerular Disease

Author

C Dechenne, Malcolm Davies, Jacqueline Foidart, Jean-Claude Davin, Jean-Michel Foidart, and P. R. Mahieu

Subjects
chemistry.chemical_classification, medicine.medical_specialty, Mesangial cell, biology, Chemistry, Glomerular basement membrane, In vitro, Sialic acid, Glycosaminoglycan, chemistry.chemical_compound, medicine.anatomical_structure, Endocrinology, Laminin, Internal medicine, medicine, biology.protein, Glomerular Filtration Barrier, Glycoprotein
Abstract

Electronegative charges of the glomerular filtration barrier play probably an important role in its impermeability to anionic proteins 1–9. Sialic acid 10 (present in laminin) and glycosaminoglycans 11 seem to be the major molecules responsible for this propriety. Neutral proteinases synthetized either by mesangial cells or by monocytes and neutrophils, infiltrating glomeruli in some pathologic states, are able to degrade GBM glycoproteins in vitro 12–14.

Published
1988

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