1. Texture-property relations of bioamine crosslinked gellan gum hydrogels
- Author
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Jari Hyttinen, Minna Kellomäki, Susanna Narkilahti, Tiina Joki, Laura Ylä-Outinen, Janne T. Koivisto, Toni Montonen, Edite Figueiras, Jenny E. Parraga, Olli Koskela, Eskola, Hannu, Tampere University, Faculty of Medicine and Life Sciences, Faculty of Biomedical Sciences and Engineering, Research group: Biomaterials and Tissue Engineering Group, Facilities and Infrastructure, Research group: Computational Biophysics and Imaging Group, and BioMediTech
- Subjects
chemistry.chemical_compound ,Materials science ,genetic structures ,chemistry ,Tissue engineering ,Soft tissue engineering ,Self-healing hydrogels ,217 Medical engineering ,Texture (crystalline) ,Optical projection tomography ,Gellan gum ,Biomedical engineering - Abstract
Gellan gum is a hydrogel with potential for soft tissue engineering but a quick and thorough method is needed for screening of different possible compositions for more extensive studies. Here optical projection tomography in bright field mode was used to image nearly transparent hydrogels to record their optical texture in 3D. The gained Haralick’s textural features were then analyzed with multiple discriminant analysis and combined with data from mechanical testing and neuronal cell culturing. We show the usefulness of optical texture analysis in screening of hydrogel compositions when aiming for tissue engineering applications. acceptedVersion
- Published
- 2017
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