1. Validation of Traditional Claim of Oxalis debilis Kunth: An Ethnomedicinal Plant from Northeastern Region of India
- Author
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Kamaruz Zaman, Julfikar Ali Junejo, and Mithun Rudrapal
- Subjects
chemistry.chemical_compound ,Activity profile ,Traditional medicine ,chemistry ,Phytochemical ,ved/biology ,ved/biology.organism_classification_rank.species ,medicine ,Ethyl acetate ,Anthelmintic ,Biology ,Oxalis debilis ,medicine.drug - Abstract
Ethnomedicinal survey documents the traditional uses of Oxalis debilis Kunth leaves in the management of diarrhea and helminthiasis. In our study, the antidiarrheal and anthelmintic activities were evaluated for ethyl acetate and hydro-alcoholic leaf extracts of O. debilis. Both the leaf extracts exhibited antidiarrheal and anthelmintic activities. The hydro-alcoholic extract exhibited better activity profile than that of ethyl acetate extract. Moreover, the anthelmintic activity was found to be more significant in comparison to the antidiarreal activity for the hydro-alcoholic extract. From phytochemical and TLC studies, the presence of phenolic compounds and flavonoids has been demonstrated in the extracts indicating their possible role in the bioactivity of O. debilis leaves. However, the potent antidiarrheal and anthelmintic activities are claimed with the hydro-alcoholic extract of O. debilis leaves. Our present work justifies the ethnomedicinal claims of O. debilis leaves in the treatment of diarrhea and helminthiasis, particularly in the northeastern region of India.
- Published
- 2021