1. Near-complete nucleotide sequence of a border disease virus genotype BDV-7 isolate from Italy
- Author
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Monica Giammarioli, Ilaria Pierini, Gian Mario De Mia, and Moira Bazzucchi
- Subjects
Genotype ,viruses ,Genome, Viral ,Biology ,Genome ,Border disease virus ,Open Reading Frames ,03 medical and health sciences ,Virology ,Animals ,Amino Acid Sequence ,Peptide sequence ,Phylogeny ,030304 developmental biology ,Whole genome sequencing ,0303 health sciences ,Sheep ,Border Disease ,Phylogenetic tree ,030306 microbiology ,Nucleic acid sequence ,General Medicine ,Open reading frame ,Italy - Abstract
To gain further insight into the genomic features of border disease virus (BDV), we determined the nearly complete genome sequence of isolate TO/121/04 from an aborted ovine fetus. Its genome contains a single open reading frame (ORF), which comprises 11,681 nucleotides encoding a polyprotein of 3893 amino acids. Phylogenetic analysis of the near full-length genome sequence showed that the BDV isolate differed significantly from all ovine pestiviruses identified so far, thus re-affirming the presence in Italy of this novel genetic group, termed BDV-7.
- Published
- 2020