1. Prevalence of hypogammaglobulinemia and its management with subcutaneous immunoglobulin supplementation in patients after allogeneic hematopoietic stem cell transplantation—a single-center analysis
- Author
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Piotr Boguradzki, Grzegorz W. Basak, Ewelina Kmin, Jarosław Biliński, Ewa Karakulska-Prystupiuk, Wiesław Wiktor Jędrzejczak, Karolina Szczypińska, Joanna Drozd-Sokołowska, Marcin Chlebus, Agnieszka Tomaszewska, Krzysztof Mądry, and Jadwiga Dwilewicz-Trojaczek
- Subjects
Adult ,Male ,medicine.medical_specialty ,Hypogammaglobulinemia ,medicine.medical_treatment ,Chronic lymphocytic leukemia ,Population ,Immunoglobulins ,Hematopoietic stem cell transplantation ,Administration, Cutaneous ,Single Center ,Allogeneic Hematopoietic stem cell transplantation (allo-HSCT) ,Gastroenterology ,Young Adult ,Agammaglobulinemia ,Internal medicine ,Prevalence ,medicine ,Humans ,Transplantation, Homologous ,education ,Retrospective Studies ,education.field_of_study ,Hematology ,biology ,business.industry ,Secondary immunodeficiencies (SIDs) ,Hematopoietic Stem Cell Transplantation ,Disease Management ,General Medicine ,Middle Aged ,medicine.disease ,Transplantation ,Hematologic Neoplasms ,Subcutaneous immunoglobulins ,Immunoglobulin G (IgG) ,biology.protein ,Female ,Original Article ,Antibody ,business - Abstract
Secondary immunodeficiencies are frequently observed after allo-HSCT. The efficacy of subcutaneous IgG preparations in this population is unknown. A retrospective single-institution study involved 126 adult patients transplanted in 2012–2019 for hematological malignancies. Patients were tested every 2–3 weeks for plasma IgG concentration during the 1st year after transplantation and supplemented with facilitated subcutaneous immunoglobulin when they either had IgG concentration
- Published
- 2021