59 results on '"Wherry, E. John"'
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2. Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial
3. A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples
4. Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
5. SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
6. Efficient engineering of human and mouse primary cells using peptide-assisted genome editing
7. Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction
8. Author Correction: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
9. Divergent clonal differentiation trajectories of T cell exhaustion
10. Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
11. Building effective collaborations for the study of COVID-19 across the severity spectrum
12. PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine
13. Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
14. Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
15. Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
16. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction
17. Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
18. New-onset IgG autoantibodies in hospitalized patients with COVID-19
19. Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy
20. Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
21. CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer
22. Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells
23. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells
24. Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
25. Defining ‘T cell exhaustion’
26. Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
27. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
28. A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma
29. A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours
30. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
31. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
32. Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function
33. T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
34. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan
35. Molecular and cellular insights into T cell exhaustion
36. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
37. Molecular regulation of effector and memory T cell differentiation
38. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
39. Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria
40. Deconstructing development
41. The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling
42. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
43. TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
44. Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
45. T cell exhaustion
46. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
47. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
48. Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses
49. Inhibitory receptors: whose side are they on?
50. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
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